64 results about "Biodegradable coating" patented technology

Biodegradable coatings that include natural biodegradable polysaccharides are described. The coating is formed from a plurality of natural biodegradable polysaccharides having pendent coupling groups.

The embodiments described herein are directed to biodegradable stents comprising an inner biodegradable metal scaffold and an outer polymeric coating. The biodegradable coating consists preferentially of biodegradable polymers and may additionally include at least one pharmacologically active substance such as an anti-inflammatory, cytostatic, cytotoxic, antiproliferative, anti-microtubuli, antiangiogenic, antirestenotic (anti-restenosis), antifungicide, antineoplastic, antimigrative, athrombogenic and / or antithrombogenic agent.

The invention provides devices for treatment of a patient, wherein at least a portion of the device is provided with a biodegradable coating composed of a blend of bioactive agent and at least two biodegradable polymers or copolymers. The invention further provides methods of treatment utilizing the devices.

The invention provides devices for treatment of a patient, wherein at least a portion of the device is provided with a biodegradable coating composed of multiple coated layers of biodegradable material. The invention further provides methods of treatment utilizing the devices.

The invention relates to biodegradable vascular supports consisting of an inner biodegradable metal skeleton and an outer polymeric coating. The biodegradable coating preferably consists of biodegradable polymers and can also contain at least one pharmacologically active substance such as an anti-inflammatory, cytostatic, cytotoxic, anti-proliferative, anti-microtubule, anti-angiogenic, anti-restenotic (anti-restenosis), anti-fungicidal, anti-neoplastic, anti-migrative, athrombogenic and / or antithrombogenic active ingredient.

A system for treating a vascular condition includes a stent having a biodegradable coating on the stent framework. The coating releases a therapeutically effective amount of therapeutic agent as a function of degradation of the coating. Also provided is a method of treating a vascular condition by placing a stent having a biodegradable coating at a treatment site and delivering a therapeutically effective amount of therapeutic agent at the treatment site as a function of degradation of the coating. Also provided is a method of improving the performance of a medical device by including a biodegradable coating on the surface of the device and releasing a therapeutically effective amount of a therapeutic agent at the treatment site as a function of degradation of the coating.

The tectorial membrane rack for aorta without inner leakage consists of one netted rack in the shape matching with aorta and tectorial membrane layer covering the rack. The present invention features that high-hydroscopicity polymer with biocompatibility is sewn to the end of the tectorial membrane to form collar-like sealing ring, which will expand to fill the interval between blood vessel and the rack after absorbing water. One kind of biodegradable coating is painted to the high-hydroscopicity material to retard its hydroscopic expansion. The said high-hydroscopicity material includes acrylic acid, acrylate, acrylamide, cellulose, etc. The present invention makes it possible to raise the safety and treating effect of operation.

Container insulation including a batt comprised of large paper particles, at least 90% of which by weight are greater than 10 mm in diameter. Less than 5% by weight binder fibers are used, which have a length of at least 20 mm. Most preferably, no binder fibers are used. Where the batts are faced with paper, the paper is coated with a biodegradable coating. The resulting product is repulpable and recyclable in accordance with Fiber Box Association (FBA) testing protocols.

A medical device having a biodegradable coating comprising an inorganic material complexed to macromolecules. Biodegradation of the biodegradable coating releases nanoparticles of the inorganic material with macromolecules complexed to the released nanoparticles. The inorganic material may be applied directly onto the medical device as a nanostructured coating or be dispersed within or under a layer of biodegradable polymer. The medical device body may comprise a biodegradable metallic material. Also provided is a method of delivering macromolecules to body tissue using the medical device of the present invention.

An implantable device includes an implantable cochlear electrode carrier for electrically stimulating cochlear tissue. A flexible lubricant coating covers the outer surface of at least a portion of the electrode carrier and may include a therapeutically effective amount of a pharmaceutical agent for surrounding tissue of the inner ear.

A food container includes: a container body made of paper, and having an inner surface defining a receiving space therein, and an outer surface opposite to the inner surface; and an inner protecting layer coated on the inner surface and made from a biodegradable coating composition including polybutylene succinate as a major component. The biodegradable coating composition further includes a minor component selected from polybutylene adipate / terephthalate, polylactic acid, and combinations thereof.

A neural probe (10) is provided for in vivo communication with biological tissue, including stimulating neurons and / or recording neural electrical activity. The probe (10) may be constructed so that the immune response by the biological tissue in which the device is implanted is reduced over known implantable probes. The probe (10) can be constructed with a tip (16) that has a branched configuration, with electrodes (24) located along each of the branches (20). A biodegradable coating (18) is disposed over at least the tip (16) of the probe (10) to provide the probe (10) with sufficient integrity for insertion into the biological tissue and to degrade after insertion. The biodegradable coating (18) can have an anti-inflammatory drug or other bioagent distributed therein for localized release of the bioagent to further reduce the immune response.

The present invention is a biodegradable resin composition having excellent physical properties such as strength, water-resistance, molding workability, thermal-resistance, and suitable for a molded article for various electric products. The biodegradable resin composition of the present invention contains a biodegradable resin and filler coated with a biodegradable coating resin in which the filler coated with the biodegradable coating resin is contained within the biodegradable resin. Preferable aspects are such as an aspect that the filler is at least one of mica, talc and montmorillonite, an aspect that a filler content of the biodegradable resin is in the range of 5 mass % to 50 mass %, an aspect that an average diameter of the filler is in the range of 0.01 μm to 200 μm, and an aspect that the biodegradable resin is polylactic acid.

A polylactic polyester resin having a chemical structure represented by Formula (1), an acid value of 300 to 2,500 eq / 106 g, a number average molecular weight of 2,000 to 50,000, and a lactic acid content percentage of not less than 40 weight %,Z—(O—(CH2CH2O)p—(CO—Y—O)q—X)r  (1)wherein Z is an r-valent organic group, Y is —CH(CH3)—, or a mixture of —CH(CH3)— and C2-10 linear or branched alkylene group, and X is a residue of a polybasic acid having 2 or more carboxyl groups, or hydrogen; each of X, Y, and Z may be one kind or a mixture of a plurality of different kinds; and p, q, and r are 0 or a positive integer, p has an average value of not less than 0.5, q has an average value of not less than 5, and r has an average value of not less than 3 and not more than 15.An aqueous dispersion, an aqueous resin composition, an aqueous adhesive, an aqueous paint, aqueous ink, a laminate made of an aqueous adhesive or aqueous ink, a packaging material, a sustained-release biodegradable coating agent, and a sustained-release biodegradable coated body comprising the sustained-release biodegradable coating agent, which contain the polyester resin.

A biodegradable outdoor insect bait station for offering a toxic bait to a target insect. The bait station includes a bait matrix together with a housing for holding the bait matrix. The bait matrix has a core of toxic bait material and a biodegradable coating. When placed outdoors, moisture permeates the coating and liquifies the bait core making the entire matrix a food source for the target insect. The housing for holding the bait matrix may also be made biodegradable.

An anchor bolt suspending array comprises a biodegradable bridging structure attachable across a concrete form or in cantilever from one side thereof conformed by folding longitudinally a corrugated cardboard panel into overlying segments each provided with a set of spaced openings that are aligned upon folding to receive the shank of an anchor bolt therein. A retainer either formed as a frustoconical cardboard pulp structure dimensioned to capture the anchor bolt shank end, or as an accordion folded corrugated cardboard strip perforated by spaced holes conformed to grasp the shank, is then useful to suspend the bolt from the bridging structure into the poured concrete. Both the retainers and the bridging structures can be color coded by a biodegradable coating in accordance with the size of the anchor bolt that is receivable therein.

The present invention is a bone growth stimulating and promoting cytokine type biological implant preferably comprising PTH coated with a controlled release biodegradable coating that is implanted preferably in the concave side of a scoliotically curved spine in combination with a bone growth inhibiting type biological implant preferably comprising methotrexate or like anti-metabolite coated with a controlled release biodegradable coating that is implanted preferably in the convex side of a scoliotically curved spine. The insertion of the biological implant is highly non-invasion, especially as compared to more conventional spine surgical methods, and the biological implant does not decrease spinal mobility or spinal range of motion.

A composition utilized to prevent the deposit of overspray, the composition comprising, based on the total weight of the composition, (a) from about 1% to about 60% by weight a blend of dibasic esters; (b) from about 10% to about 75% by weight one or more surfactants; and (c) a thickener, and methods for use. The dibasic esters are be derived from a blend of adipic, glutaric, and succinic diacids, and, in one particular embodiment, the blend comprises dialkyl methylglutarate and at least one of dialkyl adipate and dialkyl ethylsuccinate, wherein the alkyl groups individually comprise a C1-C12 hydrocarbon group. The one or more surfactants are typically chosen from alcohol alkoxylate, an alkyl phenol ethoxylate, a terpene, a terpene alkoxylate or any derivates thereof. The thickener is typically one or a combination of polyacrylates, magnesium silicates, polyvinyl alcohol, fumed silicas, guar gum, guar gum derivatives, cellulose, and cellulose derivatives.

The invention discloses an internal fracture fixation system which comprises a locking bone plate and a locking screw. The locking screw comprises a screw head, a screw tail and a screw rod located between the screw head and the screw tail. The screw rod is coated with a biodegradable coating, wherein the thickness of the biodegradable coating is smaller than or equal to the difference between the diameter of the screw rod and the intermediate diameter of the screw tail; in the biodegradable coating pre-degradation and perioperative periods, the rigidity of the locking screw is 5.0-6.5 KN / mm; after the biodegradable coating is totally degraded, the rigidity of the locking screw is 1.0-1.5 KN / mm; in the biodegradable coating gradually-compatible degrading process, the rigidity of the locking screw is decreased along with decrease of the thickness of the biodegradable coating, gradual-change micro-motion stress stimulation is formed by gaps which are gradually decreased among bone fractures and the screw rod, and porosis is promoted so that bone fracture end healing can be promoted.

The invention discloses a preparation method of a biodegradable coating material, relates to a preparation method of a coating material, and aims at solving the technical problem that an existing coated slow release fertilizer is relatively high in price. The method comprises the following steps: mixing corn starch with an enhancer, and then adding distilled water; adding a water-proofing agent and a plasticizer, and dropwise adding ammonium hydroxide and ethyl silicate, so as to prepare a film forming solution; carrying out curtain coating of the film forming solution on a polytetrafluoroethylene glass plate under the condition of room temperature; and drying and uncovering a film, so as to obtain the biodegradable coating material. The dosage of the prepared biodegradable coating for a starch-based slow-release fertilizer is 0.5%-1.0% of the total amount of the fertilizer, and the cost of each ton of fertilizer is increased by 72.1-144.2, and is improved by 2.87%-5.76% in comparison with that of common urea. The preparation method belongs to the field of preparation of a chemical fertilizer coating.

A coating matrix operable for coating fertilizer particles. The coating matrix is made from a whole biomass composition, in which said whole biomass composition comprises at least a microalgae and a macroalgae reduced to a powder form, mixed with an aqueous solution of alkali metal hydroxide or alkaline earth metal hydroxide at a concentration ranging from 0.1% to 20% (w / v). The mixture is mixed at about 7 pH to about 9.5 pH which produces a cross-linked polysaccharide.

The invention provides a poison bait capable of inhibiting rat reproduction. The poison bait comprises a component particle A and a component particle B. The component particle A is a compound bait adopting a multilayer structure, the compound bait adopting the multilayer structure comprises a degradable porous carrier which is loaded with a chemosterilant and peanut flour, a biodegradable coating layer which can internally coat the degradable porous carrier and the chemosterilant and the peanut flour loaded on the degradable porous carrier, and a food layer which comprises foods and coats the biodegradable coating layer internally in sequence from inside to outside, wherein the chemosterilant is desogestrel and ethinyloestradiol. The component particle B is a food particle. The poison bait disclosed by the invention is conducive to long-term and all-weather application, especially the sublimation, degradation or loss of effective components are avoided when the poison bait is applied and released in the field or in the wild, so that secondary pollution to the environment is not caused, and the palatability of the poison bait is good.

The invention relates to a vascular stent with a degradable drug-loaded coating and a preparation method thereof. The vascular stent includes a stent body, and also includes a calcium-phosphorus transition layer and a regenerated drug-loaded coating. The calcium-phosphorus transition layer is located on the surface of the stent body, the regenerated drug-loaded coating is located on the surface of the calcium-phosphorus transition layer, and the regenerated drug-loaded coating and the calcium-phosphorus transition layer have same ingredients and fix drugs. The contribution of the invention lies in that the vascular stent can fix drugs in a biodegradable coating without using polymer, and can control drug release by adjusting the regenerated drug-loaded coating. The experimental result shows that the polymer-free degradable drug-loaded coating can effectively inhibit vascular intimal hyperplasia and avoids the occurrence of restenosis.