Poison bait capable of inhibiting rat reproduction and preparation method thereof
A bait and rodent technology, applied in the fields of botanical equipment and methods, chemicals for biological control, animal repellents, etc. Unstable sterile effect and other problems, to achieve the effect of long duration of drug effect, reduction of secondary pollution, and good palatability
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Embodiment 1
[0026] Example 1 Calcium Carbonate Porous Carrier / Cyclodextrin Coating Layer Composite Medicinal Bait
[0027] Prepare a solution containing sodium polystyrene sulfonate and calcium nitrate, use sodium carbonate as a precipitant to precipitate calcium carbonate porous microspheres; dissolve desogestrel, ethinyl estradiol, peanut powder, and nonionic surfactants in water to configure To form an impregnating liquid, the weight ratio of desogestrel, ethinyl estradiol and peanut powder is 75:25:400, adding calcium carbonate porous microspheres into the impregnating liquid, fully mixing, heating and evaporating to obtain loaded desogestrel, Calcium carbonate porous microspheres of ethinyl estradiol and peanut powder; prepare a saturated aqueous solution of cyclodextrin, spray the saturated aqueous solution of cyclodextrin onto the porous calcium carbonate microspheres, and then heat and stand at 50°C for 12 hours to obtain cyclodextrin Fine coated calcium carbonate porous microsphe...
Embodiment 2
[0028] Example 2 Polylactic Acid Porous Carrier / Gelatin Coating Layer Composite Medicinal Bait
[0029] To prepare a solution of polylactic acid in dichloromethane, use CO 2Supercritical drying to polylactic acid porous microspheres; dissolving desogestrel, ethinyl estradiol, peanut powder, and nonionic surfactants in 33% ethanol aqueous solution to prepare an impregnation solution, desogestrel, ethinyl estradiol and peanut The weight ratio of the powder is 80:20:300. Add polylactic acid porous microspheres into the impregnating liquid, mix well, heat and evaporate to obtain polylactic acid porous microspheres loaded with desogestrel, ethinyl estradiol and peanut powder; prepare A saturated aqueous solution of gelatin, impregnating the polylactic acid porous microspheres with a saturated aqueous solution of gelatin, then heating and standing at 80° C. for 5 hours, to obtain polylactic acid porous microspheres coated with gelatin; prepare the food material, and the food materia...
Embodiment 3
[0030] Example 3 Chitosan Porous Carrier / Cyclodextrin Coating Layer Composite Medicinal Bait
[0031] Prepare chitosan acetic acid solution, add glutaraldehyde to chemically cross-link to obtain chitosan porous microspheres; dissolve desogestrel, ethinyl estradiol, peanut powder, and nonionic surfactants in water to prepare an impregnating solution, deoxidize The weight ratio of pregnene, ethinyl estradiol and peanut powder is 60:40:700. Add chitosan porous microspheres into the impregnation solution, mix well, heat and evaporate to obtain desogestrel, ethinyl estradiol and peanut powder Polylactic acid porous microspheres; prepare a saturated aqueous solution of cyclodextrin, impregnate chitosan porous microspheres with a saturated aqueous solution of cyclodextrin, then heat and stand at 60°C for 10 hours to obtain cyclodextrin-coated chitosan Porous microspheres; Prepare food material, said food material is made of 15% soy flour, 58% flour, 8% fish meal, 15% peanut powder, 2...
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