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41 results about "Artery dissection" patented technology

Covered stent for aortic dissection surgery, delivery device and use method thereof

The invention discloses a covered stent for an aortic dissection surgery, a delivery device and a use method thereof. The stent comprises a main body, wherein the main body decreases progressively from the heart near end with a large diameter to a far end with a small diameter, and the superior border of the middle piece of the main body is a rotary island; a tectorial membrane is arranged except the rotary island, and the two ends of the main body and the rotary island are provided with positioning marks. The delivery device comprises a delivery sheathing canal, a suture and a traction guide wire, wherein the suture is sewn on the outer side surface of the covered stent, and the two side edges of the covered stent at the near end of the left subclavian artery are sewn up by the suture; the stent is closed up to be in a semi-contraction state by the traction guide wire through the suture, and the covered stent is closed up and wrapped in the delivery sheathing canal; the delivery sheathing canal is provided with a steeple, and the far end of the traction guide wire penetrates through the handle of the delivery sheathing canal and is fixed. The covered stent for the aortic dissection surgery is used for a dissecting aneurysm surgery of the lesser curvature side of aortic arch and an interventional minimally invasive surgery of an aortic dissection near the brachiocephalic trunk, so that the trauma of a thoracotomy is avoided, and the athe lumen crevasse occlusion is directly implemented.
Owner:杨威

Plastic covered aortic dissection stent and aortic dissection stent

The invention discloses a plastic covered aortic dissection stent and an aortic dissection stent.The plastic covered aortic dissection stent comprises a tubular covering membrane and multiple annular supports sequentially sewn on the covering membrane in the axial direction and is characterized in that the annular supports on one part of the covering membrane are semi-sewn supports, the semi-sewn supports are provided with non-sewn areas which can be separated from the covering membrane, and the covering membrane corresponding to the internally-bent side of the non-sewn areas breaks away from the semi-sewn supports to be folded internally in a bent state.The semi-sewn supports are distributed at the bent positions after the plastic covered aortic dissection stent is implanted.The number of the semi-sewn supports is at least two sequentially-adjacent circles.When the plastic covered aortic dissection stent is bent, non-sewn areas of every two adjacent annular supports located on the internally-bent side can be overlapped, and the covering membrane in the non-sewn areas is folded towards the inside of the stent to maintain the bent state of the covered stent.
Owner:HANGZHOU WEIQIANG MEDICAL TECH CO LTD

Application of N6022 in prevention and treatment of aortic dissection and aortic aneurysm

ActiveCN111529524AInhibition of pathological expansionImprove the condition of the lesionOrganic active ingredientsCardiovascular disorderIntramural hematomaBlood vessel
The invention discloses application of N6022 in treatment of aortic dissection and aortic aneurysm, and relates to the field of cardiovascular diseases. In mouse models of aortic dissection and aorticaneurysm, dilation of aorta can be inhibited after intravenous injection of the N6022 into tail veins, thereby reducing incidence and mortality of aortic dissection and aortic aneurysm; and moreover,the N6022 is capable of reducing rupture of aortic aneurysm, inhibiting occurrence of hematoma in inner walls of lumen and excessive collagen deposition on vascular walls, maintaining integrity of elastic fibers in the vascular walls, and treating the aortic dissection and the aortic aneurysm. The application of the N6022 in the treatment of the aortic dissection and the aortic aneurysm opens upa new application field of the N6022, and provides a meaningful reference for the prevention and the treatment of the aortic dissection and the aortic aneurysm diseases as well as improvement of vascular lesions.
Owner:NANJING MEDICAL UNIV

Aortic dissection vascular stent and manufacturing method thereof

The invention discloses an aortic dissection vascular stent and a manufacturing method thereof. The aortic dissection vascular stent comprises a stent body and a membrane attached to the outer side of the stent body, the stent body is formed by multiple coils in a spiraling mode, and each coil is formed by multiple waves. The manufacturing method includes the steps that a spatial continuous spiral wave curve is constructed through a spatial cylindrical coordinate system; a three-dimensional model of the stent body is obtained in a scanning mode; an entity model of the stent body is made according to the three-dimensional model; a metal wire is wound around the entity model to obtain the stent body; heat shaping and electropolishing are carried out on the stent body; the membrane is arranged on the outer side of the stent body in an electrospinning or hot-pressing mode. Bending of the vascular stent in the bent lumen is uniformly distributed in the whole vascular stent, so that the fitness of the vascular stent is improved, and the situation that the vascular wall is bent or damaged is avoided. Besides, the vascular stent is specially designed for the aortic dissection and is simple in structure, convenient to operate, appropriate in supporting force and suitable for the pathological characteristics of the aortic dissection.
Owner:SHANGHAI CHANGHAI HOSPITAL +2

Aortic dissection detecting marker and marker evaluation method

The invention belongs to the technical field of medicine and discloses an aortic dissection detecting marker and a marker evaluation method. The aortic dissection detecting marker is MMP-9+D-Dimer+ET-1+Calponi. The evaluation method comprises the following steps: performing serological analysis on the selected marker MMP-9+D-Dimer+ET-1+Calponi with ELISA; drawing a ROC (receiver operating characteristic) curve and adopting statistical software SPSS21.0 for analysis. Specificity of three indexes including ET-1, D-Dimer and MMP-9 are higher and are 98.6%, 98.7% and 97.1% respectively, sensitivity of the three indexes are 80.0%, 81.7% and 81.7%, and diagnostic accuracy of the three indexes are also higher and are 86.4%, 87.5% and 87.5%.
Owner:THE FIRST TEACHING HOSPITAL OF XINJIANG MEDICAL UNIVERCITY

Diagnostic marker for aortic dissection and application thereof

The present invention discloses a diagnostic marker for aortic dissection. The diagnostic marker comprises at least one of a protein inhibitor 16 and fibrinogen-like protein 1. The present invention also discloses an application of the diagnostic marker for aortic dissection in diagnosis of the aortic dissection, an application of the diagnostic marker for aortic dissection in production of diagnostic products for diagnosis of the aortic dissection, an application of the diagnostic marker for aortic dissection for distinguishing the aortic dissection from acute coronary syndrome and an application of the diagnostic marker for aortic dissection in production of diagnostic products for distinguishing the aortic dissection from acute coronary syndrome. The diagnostic marker for aortic dissection is screened out by proteomic principles, and verified by a large number of samples. The diagnostic marker for aortic dissection can effectively improve diagnostic rate of the aortic dissection anddiagnostic rate for distinguishing the aortic dissection from acute coronary syndrome.
Owner:ZHUJIANG HOSPITAL SOUTHERN MEDICAL UNIV

Aortic dissection vessel stent and manufacturing method thereof

The invention discloses an aortic dissection vascular stent and a manufacturing method thereof. The aortic dissection vascular stent comprises a stent body and a membrane attached to the outer side of the stent body, the stent body is formed by multiple coils in a spiraling mode, and each coil is formed by multiple waves. The manufacturing method includes the steps that a spatial continuous spiral wave curve is constructed through a spatial cylindrical coordinate system; a three-dimensional model of the stent body is obtained in a scanning mode; an entity model of the stent body is made according to the three-dimensional model; a metal wire is wound around the entity model to obtain the stent body; heat shaping and electropolishing are carried out on the stent body; the membrane is arranged on the outer side of the stent body in an electrospinning or hot-pressing mode. Bending of the vascular stent in the bent lumen is uniformly distributed in the whole vascular stent, so that the fitness of the vascular stent is improved, and the situation that the vascular wall is bent or damaged is avoided. Besides, the vascular stent is specially designed for the aortic dissection and is simple in structure, convenient to operate, appropriate in supporting force and suitable for the pathological characteristics of the aortic dissection.
Owner:SHANGHAI CHANGHAI HOSPITAL +2

Application of R-ketorolac in prevention and treatment of aortic dissection and aortic aneurysm

ActiveCN113712960AInhibition of pathological expansionInhibition of hematomaOrganic active ingredientsAntineoplastic agentsIntramural hematomaKetorolac
The invention provides application of R-ketorolac in prevention and treatment of aortic dissection and aortic aneurysm. The R-ketorolac is orally taken to inhibit pathological expansion of aorta and reduce the occurrence rate and death rate of the aortic dissection and aortic aneurysm; and the R-ketorolac can inhibit the occurrence of vascular wall inflammatory reaction, reduce rupture of aortic aneurysm bodies, inhibit the occurrence of hematoma in the inner wall of a lumen, maintain the integrity of vascular wall elastic fibers and treat the aortic dissection and aortic aneurysm. The invention develops a new application field of the R-ketorolac, and provides a significant reference for preventing and treating aortic dissection and aortic aneurysm diseases and improving vascular lesion conditions.
Owner:NANJING MEDICAL UNIV

Compound preparation containing benidipine hydrochloride and metoprolol tartrate and application thereof

The invention discloses a compound preparation containing benidipine hydrochloride and metoprolol tartrate and an application thereof; for the preparation, the benidipine hydrochloride and the metoprolol tartrate are taken as active pharmaceutical ingredients. The compound pressure-reducing preparation adopts drug combination and is good in efficacy, less in side effects and high in performance-price ratio; the compound preparation is taken once per day, the administration is convenient and the drug compliance of a patient can be improved. The preparation can be prepared into oral formulations in different forms, thereby realizing synergic and complementary action of drugs and enhancing the treatment effect of the compound preparation. The compound preparation has significant effects for treating hypertension and can also be used for treating angina pectoris, myocardial infarction and arrhythmia, as well as hypertrophic cardiomyopathy, aortic dissection, hyperthyroidism, cardiac neurosis, chronic stable heart failure and other symptoms. The compound preparation is low in price, simple to prepare and convenient to popularize and apply.
Owner:山东新宝医药有限公司

Medicine for treating artery-related diseases and application thereof

The invention provides a medicine for treating artery-related diseases and an application thereof. Specifically, the invention provides an application of the compound shown in the formula I in treating artery related diseases. Experiments show that the compound shown in the formula I has a remarkable curative effect on arterial lesions such as aneurysm, interwall hematoma and / or arterial dissection.
Owner:SHANGHAI INST OF MATERIA MEDICA CHINESE ACAD OF SCI

The anchoring of an anchoring of an anatomical anchoring and the anchoring of the anchor and the conveyor system

ActiveCN109172043BSecurity anchoring methodNo entry into the false cavityStentsBlood vesselsThird aortic archDelivery system
An ascending aorta repair stent anchored by the innominate artery, including the ascending aorta stent segment and the innominate artery stent segment, the innominate artery part of the stent is first released, and then the main part is released, and the distal opening of the main part is facing the aortic arch lumen far away end, the main part of the stent covers the primary tear of the ascending aorta with dissection. After release, the body portion terminates above the sinotubular junction. The longitudinal beam structure is made of temperature-dependent shape-memory metal materials extending to the greater curvature of the aortic arch and the lesser curvature of the aortic arch that continue to the innominate artery. Stick to the aortic wall. The stent is anchored only by the special anatomical shape of the ascending aorta and the innominate artery and the memory metal stringer structure. It is used for patients with type A aortic dissection who are waiting for surgery when there are surgical contraindications in the acute stage, and provides opportunities for follow-up surgical treatment for patients with acute type A aortic dissection with high surgical risk.
Owner:FUWAI HOSPITAL CHINESE ACAD OF MEDICAL SCI & PEKING UNION MEDICAL COLLEGE
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