The invention discloses dampness-removing and pain-relieving powder, which is prepared from the following components in parts by weight: 1 to 8 parts of scorpion, 1 to 8 parts of centipede, 2 to 14 parts of stiff silkworm, 2 to 14 parts of earthworm, 1 to 8 parts of dragon's blood, 6 to 25 parts of radix aconiti preparata, 6 to 25 parts of radix aconiti kusnezoffii preparata, 2 to 13 parts of aconitum brachypodum, 6 to 25 parts of spiderflower seed and 0.1 to 1.5 parts of borneol. Through scientific proportioning of the medicinal materials, the traditional Chinese medicine composition has the effects of dispelling wind and cold, eliminating dampness, relieving pain, nourishing blood, promoting blood circulation, relaxing tendons, warming and nourishing liver and kidney, strengthening tendons and bones, clearing and activating the channels and collaterals, strengthening the body resistance, eliminating evil, enhancing the immunity of the organism and repairing damaged bone joints and tissues around the joints, so that the curative effect of getting twofold results with half the effort is achieved. The dragon's blood has the effects of replenishing blood, activating blood circulation to dissipate stasis, promoting blood circulation, improving nutrition of joints and other parts and repairing muscles and ligaments of diseased regions. Earthworm and centipede pine have the effects of calming endogenous wind, relieving convulsion, activating meridians to stop pain, expelling wind-damp and relaxing tendons; dragon's blood can activate blood, dissipate blood stasis and relieve pain; the stiff silkworm has the effects of dispelling wind, reducing phlegm, removing stasis and promoting menstruation, and the radix aconiti preparata has the effects of dispelling wind-cold, removing dampness, warming meridians, dredging collaterals, resisting wind-cold, diminishing inflammation, easing pain, inhibiting rheumatic inflammatory hyperplasia and relieving inflammatory response of synovial tissues.