93results about How to "Useful in treating" patented technology

The invention provides a method for determining the efficacy of a TNFα inhibitor, such as a TNFα antibody, or an antigen-binding portion thereof, for treating ankylosing spondylitis (AS), using a collagen degradation biomarker and/or a synovitis biomarker.

A pressure sensor for an extracorporeal circulating circuit includes a liquid chamber, a pressure measuring means, and a liquid flow path. The liquid chamber includes a reference surface not deformed by a pressure in the extracorporeal circulating circuit, a deforming surface disposed separated from the reference surface and deformed at least partially by a pressure in the extracorporeal circulating circuit, a first connection surface that joins the deforming surface with the reference surface to form a closed liquid-tight space inside them and is not deformed by a pressure in the extracorporeal circulating circuit, a liquid inflowing port provided in the side surface of the first connection surface, and a liquid outflowing port disposed away by ½ to less than one round from the inflowing port in the flowing direction of liquid introduced along the inner periphery of the side surface of the first connection surface. The pressure measuring means measures the deformation amount of the deforming surface, and is disposed outside the liquid chamber; and the liquid flow path is liquid-tightly connected with the liquid inflowing port so that liquid to be introduced into the liquid chamber flows in along the inner periphery of the side surface of the first connection surface.

Provided is a monoclonal antibody which specifically recognizes B cell lymphoma cells and a use thereof. More specifically, provided are the monoclonal antibody; a pharmaceutical composition for preventing or treating B cell lymphoma including the monoclonal antibody; a composition for diagnosing B cell lymphoma including the monoclonal antibody; a method for providing information for diagnosing B cell lymphoma using the monoclonal antibody; a chimeric antigen receptor (CAR) protein including i) the antibody, ii) a transmembrane domain, and iii) an intracellular signaling domain; a recombinant vector which expresses the CAR protein; a CAR-modified T cell transformed with the recombinant vector; a pharmaceutical composition for preventing or treating B cell lymphoma including the CAR-modified T cell; and an antibody-drug conjugate wherein the monoclonal antibody and a drug are conjugated.

Water and fuel contaminating material may be removed from a stream operating engine. A suitable membrane material is supported in a suitable housing. At least a portion of the contaminated oil stream is flowed over one side of the membrane and water and fuel material diffuses through the membrane to its other side where they are gathered and removed from the housing. The water and fuel material may be recovered separately using different membranes or different regions of a membrane. They may be swept from the membrane and housing a flow of air for disposition outside the housing.

A massage implement consisting of two elements. One element is a metal tube that receives an adjustable insert therein. The insert and the tube are adjustable in length relative to each other. The metal tube has at its top a T-shaped configuration attached thereto which is made of a hard rubber or plastic material. The sliding insert is made of hard rubber or a plastic material and has a way of arresting the sliding insert therein after a predetermined length has been established. The sliding insert has at its bottom replaceable massaging tools thereon. The different massaging tools are used for treating different areas on the body of a patient. The massage implement is used by a therapist by placing the T-shaped configuration in the area of the armpit and by applying pressure to any of the bottom massage tools. The pressure is applied by the weight of the body of therapist.

Bone screws suitable for use with treatment of bones such as phalanges, particularly distal or terminal phalanges, and methods of using the bone screws are disclosed. Exemplary bone screws include a shaft having a thread about at least a portion of the shaft and at least one blade attached to the shaft. The at least one blade can be configured to bury into a bone to capture bone fragments and/or to securely attach to a bone.

A method and composition is described for controlling the growth of fouling materials, such as scale, in aqueous systems using a tagged (fluorescent) polymer. The tagged polymer can be a fluorescent polymer which has at least one fluorescent monomeric unit derived from a fluorophore which has at least one terminal end comprising an olefinic group. The method of controlling the growth of at least one fouling material in an aqueous system can include the steps of adding the tagged polymer to the aqueous system to be treated, fluorometrically monitoring the concentration of the tagged polymer, and adjusting, as needed, the concentration of the tagged polymer and proportionally used water treatment compound or compounds effective to control the growth of at least one fouling material. The adjustment of pH before determination of the fluorescence signal can be employed to increase sensitivity of the fluorophore and minimize background interference.

A shoe for a hoofed animal, e.g. a horseshoe, is described which comprises a body made from a thermoplastic composition which comprises a matrix of a thermoplastic material which has a softening point of less than 100° C., such as a polycaprolactone. A method of shoeing a hoofed animal, such as a horse, is also described.

The tinnitus testing apparatus of this invention comprises a control part that in turn comprises: an auditory stimulus generation part that can generate a stimulus; and an AEP acquisition and amplitude measurement part that can acquire auditory evoked potential (AEP) brain waves of a examinee due to said stimulus and measure the specific amplitude of said acquired brainwaves; wherein said auditory stimulus is one or more of: a 1st stimulus containing continuous noise and pulse noise; and a 2nd stimulus containing pulse noise and continuous noise with a silent gap.

A resonant transducer comprising:

a vibration plate; and

a piezoelectric element including a piezoelectric film and an upper electrode,

wherein a difference between a Young's modulus of the vibration plate and a Young's modulus of the piezoelectric film is not more than 20% with respect to the Young's modulus of the vibration plate.