93results about How to "Reduce sequelae" patented technology

The invention relates to a stent vessel for interventional therapy and a dedicated traction tool for implanting the stent vessel into a human body. The stent vessel comprises an artificial or animal vessel and support rings, wherein the support rings in three structures are used for fixation and respectively arranged at the outlet end and the inlet end of the artificial or animal vessel, and in the support rings, a detachable support ring with radial resilience force is further provided. The dedicated traction tool is especially suitable for dragging a Y-shaped stent into circuitous or narrow parts of the human body. The stent vessel provided by the invention is extremely flexible and easy to be implanted into a branch vessel until to the circuitous part. Because the main part and the branch of the stent vessel are integrated, the stent vessel is easy to position and safe and reliable without leakage after being implanted into the human body; and as the structure is simple and the cost is low, stent vessels in various diameters, variable diameters and lengths are be made, and the application range is wide because of no limit to lengths.

The invention relates to a quick diagnostic kit used for testing four or more than four kinds of invasive candidas and an application method thereof. The quick diagnostic kit is characterized in that the kit is internally provided with fluorescent quantitative PCR reaction liquid containing specific primers and fluorescent probes corresponding to the candidas which are at least four kinds as well as positive control materials and negative control materials of the candidas which are at least four kinds; Ct value tested by a fluorescent quantitative PCR tester is used for judging. The kit has the characteristics of good specificity and high sensitivity; due to double control of high specificity amplification of the primers and high specificity hybridization of the fluorescent probes, the false positive is low; therefore, the invention can be used for simultaneously testing four kinds of invasive candidas which have different sensitivities for clinical first-line antifungal drugs such as fluconazole and the like in a simple, convenient, rapid, special and sensitive way.

The invention provides eye drops and a preparation method thereof, and relates to the eye drops. The invention provides the eye drops which have the advantages of shorter action time, lower cost, better effect and capacity of resisting corneal neovascularization and quickly repairing epithelium compared with the conventional eye drops, and a preparation method thereof. The eye drops comprise the following components in percentage by volume: 0.1 to 5 percent of bovine serum, 5 to 15 percent of thickener, 1 to 5 percent of pH regulation solution, 0.1 to 2 percent of osmotic pressure buffer, 0.5to 2 percent of antibiotic, 5 to 30 percent of original solution of kallikrein-binding protein (SA3K) and the balance of balanced salt solution. According to a prescription of the eye drops, the preparation method comprises the following steps of: adding the thickener, the bovine serum, the antibiotic and the original solution of SA3K into the balanced salt solution; uniformly mixing; regulating the pH value to be 7.2 to 7.4 by using the pH regulator; regulating the osmotic pressure to be 350 to 380mOsm / L by using the osmotic pressure buffer; and filtering and degerming by using a membrane toobtain the SA3K eye drops.

The invention relates to image analysis and positioning and relates to the CT (Computer Tomography) technical field. A dual-energy CT scan data based detection method for reconstructing a projected image aims at obtaining the image so as to be beneficial to the improvement of the positioning accuracy and the tracking accuracy, wherein the image is high in contrast ratio and a certain structure of the image is eliminated selectively. According to the technical scheme, the dual-energy CT scan data based detection method includes that the formula of a dual-energy subtraction angiography image is as follows and parameters and instructions in the formula are as follows. The dual-energy CT scan data based detection method for reconstructing the projected image is mainly applied to CT.

The invention provides a triple fluorescence quantitative reverse transcription-polymerase chain reaction (RT-PCR) detection kit, which comprises quantitative RT-PCR reaction liquid, standard substances and reference substances. A kit body is provided with container holes in which quantitative RT-PCR reaction liquid tubes, a Sapovirus standard substance tube, an astrovirus standard substance tube, an adenovirus standard substance tube, a positive reference substance tube and a negative reference substance tube are arranged respectively, wherein the quantitative RT-PCR reaction liquid tubes are separately arranged and arrayed in a matrix; the standard substances are standard substances for Sapovirus, astrovirus and adenovirus; and the reference substances are positive and negative reference substances. By a real-time fluorescence quantitative RT-PCR technology, three kinds of virus specific primers and specific fluorescent probes are adopted, the design is reasonable, the kit can detect the Sapovirus, astrovirus and adenovirus from a sample through PCR reaction, and the detection method is simpler, quicker and more accurate.

The invention relates to a multifunctional electric sickbed. The multifunctional electric sickbed comprises a bed board, a bed frame and wheels. The bed board comprises a lying part, a backrest part and a supporting leg part, wherein the backrest part and the supporting leg part are arranged at the two ends of the lying part in a rotating and adjusting mode. The multifunctional electric sickbed further comprises a first adjusting mechanism, a second adjusting mechanism and a third adjusting mechanism, wherein the first adjusting mechanism and the second adjusting mechanism are used for adjusting one end of the backrest part and one end of the supporting leg part to ascend or descend; the third adjusting mechanism adjusts the bed board to ascend or descend. Particularly, the bed frame can be movably arranged in the height direction of the bed frame, the third adjusting mechanism comprises two lifting units, the two lifting units are arranged at the two ends of the bed frame and are independent of each other, and the two lifting units can lift or lower the two ends of the bed board synchronously or asynchronously. The multifunctional electric sickbed can meet the inclination requirement that the head of a patient is lower than the feet or the head is higher than the feet after an operation, the curing effect is improved, and sequelae of the patient after the operation are avoided. Meanwhile, the multifunctional electric sickbed is simple in structure, convenient to implement, low in manufacturing price and practical.

The invention belongs to the field of biology, and relates to early stage detection molecular marker of early stage Angiostrongylus cantonensis disease, and primer and correlated kit thereof. The necessary composition of the diagnostic reagent contains: aca-miR-146a-5p sequence and three related primers (stem loop primer, upstream and downstream primer) designed according to the sequence design. The invention firstly provides an application of aca-miR-146a-5p in preparation for diagnosis of Angiostrongylus cantonensis disease. The diagnostic reagent can accurately and simply detect infection of Angiostrongylus cantonensis at early stage, and can distinguish between meningitis or encephalitis caused by Angiostrongylus cantonensis and other meningitis or encephalitis with good social and economic benefits.

The invention discloses a multiplex real-time fluorescent quantitative PCR (Polymerase Chain Reaction) rapid diagnosis kit for five porcine diarrhea viruses. The rapid diagnosis kit comprises five pairs of virus specific primers, fluorescent quantitative PCR reaction liquid, a positive reference substance, a negative reference substance and a quantitative PCR standard substance. The invention further discloses application of the kit to multiplex real-time fluorescent quantitative detection of five porcine diarrhea virus infection; and the five porcine diarrhea viruses refer to TGEV, GAR, GCR, PEDV and PCV2.

The invention discloses a mouth gag. The mouth gag comprises a supporting base and a threaded rod. L-shaped supporting arms are hinged to the two ends of the supporting base and sleeved with protective sleeves in a matched mode, the mouth gag further comprises nuts in threaded fit with the tail ends of the L-shaped supporting arms, trays are installed on the nuts, and when the L-shaped supporting arms are placed in the oral cavity of a patient, the two trays are arranged to make contact with the upper jaw and the lower jaw of the patient respectively. When the L-shaped supporting arms are taken out of the protective sleeves, after the nuts are in threaded fit with the tail ends of the L-shaped supporting arms, the trays are fixed to the tail ends of the L-shaped supporting arms; when the L-shaped supporting arms stretch deep into the oral cavity of the patient, the trays make direct contact with the upper jaw or the lower jaw of the patient, and the contact area between the L-shaped supporting arms and the upper jaw or the lower jaw of the patient is increased, so that stress, acting inside the oral cavity, of the L-shaped supporting arms is dispersed to reduce the pressure, borne by the oral cavity of the patient, of the L-shaped supporting arms, and the post-operation sequelae of the patient are reduced.

The invention discloses a preparation method of a 3D printed degradable vascular stent. The method includes the following steps that (a), three-dimensional models of a mold core and an intravascular stent are built; (b), the mold core is prepared, a gelatin layer is prepared through electrospinning, and the gelatin layer is polished to be smooth, a mixture of polylactic acid and polycaprolactone are added into clean 3D printing equipment, secondary 3D printing is performed, a stent body is printed on the gelatin layer of the mold core, and development rings are printed on the two ends of the stent body before the stent body is cured completely; (c), a liquid drug-loaded mixture is sprayed on the outer surface of the stent body through ultrasound, and the mold core is removed to obtain thehollow tubular vascular stent. Through the combination of the 3D printing technology and ultrasonic spraying, the personalized stent can be prepared, and drugs can be uniformly loaded on the stent. Moreover, the stent is made from biodegradable macromolecule materials and can degrade in vivo, and sequelae are reduced.

The invention relates to a thrombus treatment system which comprises a first catheter, a second catheter, a plugging device and a stirring device, the first catheter is provided with a first channel,the second catheter is provided with a second channel, the plugging device comprises a third catheter and a plugging device which is arranged at the far end of the third catheter and has an open stateand a closed state, the stirring device comprises a first sheathing canal, a second sheathing canal arranged outside the first sheathing canal in a sliding and sleeving mode and a stirring assembly arranged at the far end of the first sheathing canal. A large amount of thrombus in the inferior vena cava can be removed under the condition that relative safety is guaranteed, the venous valve and the venous vessel wall are protected, the blood loss amount is controllable, the operation steps are simple, operation is more convenient, the operation time can be shortened, and the hospitalization cost of a patient is reduced.

The invention relates to a rapid diagnosis kit for detecting three or less invasive candida, which comprises a kit, and is characterized in that: 1) a fluorescent quantitative PCR reaction liquid, 1-3 invasive candida positive quality control materials and negative quality control materials are provided in a kit; 2) a fluorescent quantitative PCR reaction liquid contains a specific primer and a fluorescent probe; 3) the positive quality control materials are DNA samples obtained by boiling of one, optional two or three combination of the standard strains of the candida; the negative quality control materials are sterilized distilled water for three times. The application method comprises following steps: extracting DNA from the sample to be detected; 2) adding the DNA and the positive quality control materials with the equal amount to the PCR reaction system containing the fluorescent quantitative reaction liquid; 3) detecting with the fluorescent quantitative PCR detector, judging the detection result based on the Ct value of the reaction result. The invention can synchronously detect 1-3 invasive candida, provides the evidence for the early pathogen diagnosis of the clinical invasive candidiasis and reduces death rate and sequelae.

The invention provides a membrane oxygenator with high-efficiency gas-fluid exchange. The membrane oxygenator mainly comprises parts including a carbon discharge chamber, an oxygenation chamber, a temperature control chamber, a vacuum pump, a pure oxygen cylinder, a flow meter and the like. When flowing through a hollow silicone hydrogel tube placed in the carbon discharge chamber, venous blood drained from a human body permeates a tube wall to release carbon dioxide into a chamber body; a vacuum pump is utilized to apply micro-negative pressure to the carbon discharge chamber, so that the carbon dioxide is efficiently discharged; then the blood flows into a hollow silicone hydrogel spiral tube placed in the oxygenation chamber, and the pump is utilized to apply micro-positive pressure tothe oxygenation chamber, so that oxygen enters the blood efficiently and is combined with red blood cells; and the carbon discharge chamber and the oxygenation chamber are both placed in the temperature control chamber. The membrane oxygenator of the invention performs discharge of the carbon dioxide and absorption of oxygen in the blood step by step, and supplemented by a moderate negative pressure environment and positive pressure environment, the gas-fluid exchange efficiency can be effectively improved, the situation that acral necrosis of a patient is caused by using an existing oxygenator for long term to threaten life is avoided, the treatment rate is increased and sequelae are reduced.

The invention provides a percutaneous tracheostomy device, comprising a lacerable catheter sheath, a trachea catheter and a puncture needle, wherein the lacerable catheter sheath is provided with a sheath catheter with a hollow cavity, and a sheath catheter joint fixedly connected with one end of the sheath catheter; the trachea catheter comprises a trachea cannula and enters the sheath catheter cavity of the lacerable catheter sheath via the sheath catheter joint, and parts of the trachea catheter are left out of the trachea catheter joint; the puncture needle head passes through the lacerable catheter sheath through the trachea cannula cavity to be exposed out of the lacerable catheter sheath; the tail of the puncture needle is left out of the trachea cannula; the puncture needle punctures through a catheter and introduces the trachea catheter and the lacerable catheter sheath to enter the catheter; the puncture needle is pulled out from the sheath catheter cavity, and the lacerable catheter sheath is torn; parts of the trachea catheter are left in the catheter, and parts of the trachea catheter are left out of the catheter.

The invention relates to a gravity-free suspension treatment system which comprises three parts, namely a treatment instrument, a treatment device and a control system. The gravity-free suspension treatment system is characterized in that the treatment instrument and the treatment device constitute a main structure of the treatment system together and are connected with the control system to constitute a complete and intelligent sterile isolation, treatment space and gravity-free suspension treatment integration structure; the treatment instrument consists of an ozone fog generating device, an absorption and decomposition device and a handheld therapeutic equipment; the treatment device is composed of a bed body, a therapeutic chamber and a gravity-free suspension bed; the control system is composed of a control panel, a treatment instrument controller, a treatment device controller and a line controller / remote controller. According to the gravity-free suspension treatment system, ozone fog and gravity-free suspension bed treatment and an automatic control technology are integrated, and brand-new sterile isolation and gravity-free suspension treatment can be performed on patients with body surface wounds such as extensive burn, so that great progress of a technology for treating body surface wounds such as extensive burn and upgrading of innovative clinical treatment equipment are realized.

The invention discloses a traditional Chinese medicine composition for treating central retinitis, which is prepared from the following raw materials in parts by weight: 10-40 parts of phaseolus calcaratus, 1-16 parts of rhizoma alismatis, 5-25 parts of poria, 1-16 parts of radix stephaniae tetrandrae, 2-22 parts of radix astragali, 5-25 parts of radix salviae miltiorrhizae, 1-20 parts of Chinese angelica, 1-20 parts of rhizoma atractylodis macrocephalae, 5-25 parts of earthworm, 1-20 parts of herba epimedii, 1-20 parts of cassia twig, 8-28 parts of caulis spatholobi and 1-13 parts of liquorice root. The traditional Chinese medicine composition disclosed by the invention has moderate property and good curative effect, and is used for treating central retinitis without laser photocoagulation.

The invention provides a bird-nest vibration waterbed for newborn nursing. The bird-nest vibration waterbed for newborn nursing comprises a water bag cushion, a water injection port is arranged on thewater bag cushion, an air bag is arranged in the water bag cushion, an air inlet is formed in the air bag and extends out of the surface of the water bag cushion, and the edge of the joint of the airinlet and the surface of the water bag cushion is sealed; the air inlet and an air outlet of an inflator are in butt joint, and a compressor rod of the inflator is in braking connection with a telescopic rod of a motor. The bird-nest vibration waterbed for newborn nursing can better simulate vibration in a uterus, so that growth and development of a newborn are promoted; the back of the child patient is supported by means of vibration, so that the bird-nest vibration waterbed for newborn nursing plays a part in exciting the respiratory center, supporting the back for respiration and stimulating the respiratory muscles to make the child patient restore autonomous respiration, and then the purpose of treating apnea of the newborn is achieved.

The invention discloses an eyedrop which has the pH value of 7.2-7.4 and comprise the following components in percentage by volume: 10%-15% of UNC5B recombinant protein, 0.1%-5% of bovine serum, 5%-15% of a thickener, 1%-5% of a pH regulator and 0.5%-2% of antibiotics; a solvent is a balanced salt solution. A preparation method of the eye drops is simple, reliable and easy to perform; the eye drops are simple in component, relatively low in cost and convenient to prepare.

The invention belongs to the technical field of medicine and pharmacology, and discloses a drug for treating cerebral apoplexy and a construction method of an endogenous stem cell expression animal model, and the drug for treating cerebral apoplexy is liver-softening collateral-dredging decoction. The number of rat brain tissue BrdU, BrdU / NeuN and BrdU / GFAP positive cells in each group at each time point is detected through an ischemia reperfusion model caused by middle cerebral artery occlusion, and the influence of the liver softening and collateral dredging soup on proliferation and differentiation of endogenous neural stem cells of rats with ischemic brain injury is analyzed. According to the method, an improved Longa method is adopted to manufacture an ischemia-reperfusion brain injury model caused by MCAO type middle cerebral artery occlusion of rats; it is verified that the liver-softening collateral-dredging decoction promotes proliferation of endogenous neural stem cells of ischemia-reperfusion brain injury rats, differentiates the endogenous neural stem cells into mature neurons, inhibits excessive proliferation of astrocytes, promotes nerve regeneration and repair and improves nerve functions.

The invention discloses a neuroendoscopic craniocerebral surgical channel device, which comprises a protective sheath and an elastic film tube. The protective sheath comprises a movable half sheath and a fixed half sheath; the movable half sheath comprises a first half barrel, and the side wall of one end of the first half barrel is provided with a first handle in a radial extending manner; the fixed half sheath comprises a second half barrel, and the side wall of one end of the second half barrel is provided with a second handle in a radial extending manner; the tail end of the first handle and the tail end of the second handle are hinged mutually, and lateral openings of the first half barrel and the second half barrel are in opposite arrangement; the first handle is provided with a width adjusting structure, and the width adjusting structure can be driven to enable the first half barrel to move away from or close to the second half barrel; the elastic film tube is in a tubular structure and sleeves the outer surfaces of the movable half sheath and the fixed half sheath. The neuroendoscopic craniocerebral surgical channel device has advantages of simple structure and simplicity and convenience in operation; due to a closed state in puncture, brain tissues can be better protected, compression injuries are alleviated, and postsurgical complications and sequelae can be reduced.

The invention discloses an oral cavity expander with the protecting function. The oral cavity expander with the protecting function comprises a supporting base and a conical screw which penetrates through the supporting base and is matched with the supporting base in a threaded mode, wherein L-shaped supporting arms are hinged to the two ends of the supporting arm, a rotary head is fixed to one end of the screw, the other end of the screw is placed between the two L-shaped supporting arms, protrusions are arranged on the two sides of the edge, away from the screw, of each L-shaped supporting arm, and the L-shaped supporting arms are sleeved with protective sleeves which are matched with the supporting arms. The oral cavity expander with the protecting function further comprises sterilization layers, wherein the sterilization layers are arranged between the L-shaped supporting arms and the protective sleeves in a sliding mode. According to the oral cavity expander with the protecting function, the two sterilization layers are additionally arranged in the protective sleeves respectively, in this way, the L-shaped supporting arms are under a clean and sanitary environmental condition all the time, the oral cavity expander can be used for a patient simply by opening the protective sleeves by a user, the process of soaking an existing oral cavity expander in a disinfectant for a period of time before being used when the oral cavity is expanded is omitted, preparation time before first-aid is greatly shortened, and the forceful guarantee is provided for successful rescue of the patient.

The invention relates to the technical field of medicines and particularly discloses application of ilexgenin A in preparation of anti-atherosclerosis drugs. The research finds that ilexgenin A has a good effect on resisting atherosclerosis, and can obviously inhibit the formation of foamed cells in a certain concentration range. The whole experiment shows that ilexgenin A has an improvement effect on Apo E<- / -> mice atherosclerosis. Compared with the existing anti-atherosclerosis drugs, the drug prepared from ilexgenin A has the advantages of high efficiency, multiple targets and low toxic and side effects.