32results about How to "Reduce bioburden" patented technology

An injection member penetrates an elastic septum of a device defining a sealed, empty, sterile chamber in fluid communication with the septum. During penetrating, an annular interface is formed between the septum and the injection member extending axially between a penetration point on an interior surface of the septum in fluid communication with the sterile chamber, and an exterior surface of the septum engaging the injection member. The injection member is de-contaminated by (i) friction between the septum and injection member at the annular interface, and (ii) elongation of the septum at the annular interface. A substance is introduced through the injection member and into the sterile chamber of the device, the injection member is then withdrawn from the septum, the septum reseals itself at the resulting penetration aperture, and the chamber is maintained sterile throughout the foregoing steps.

A method for preparing a sterilized human acellular dermal allograft where the dermal allograft is sterilized by irradiation and has a greatly reduced bio-burden and enzymatic and antigenic activity. This product line of allografts can be easily used by surgeons in soft tissue replacement or repair and has an extended shelf life, of up to at least about three years.

Medical devices such as medical containers can be formed of glass and annealed which produces a clean device having a low bio-burden, or formed by plastic molding which produces a clean device. The clean devices are immediately transferred to a controlled environment such as a clean room or localized area to avoid the need to maintain cleanliness levels in an entire room. Syringe tip closures can be introduced into the housing assembly, where syringe barrels and tip closures are cleaned with filtered ionized air and the tip closures are coupled to the barrels. The syringe barrels can be filled with a substance and a closure member attached. While still in the housing assembly the syringe barrels can be formed into an array and placed in a clean outer container, which is then closed and sealed.

The invention relates to a city watercourse drain outlet sewage treatment method. The method mainly comprise the steps of regulation, wherein sewage is introduced into a regulating reservoir for regulation; mixing with flocculant, wherein sewage in the regulating reservoir is led out to be mixed with flocculant; flocculent settling, wherein sewage mixed with flocculant is sequentially introduced into a baffle flocculation reaction tank and a settling tank for sewage flocculation and sludge precipitation separation; denitrification, wherein water discharged from the settling tank and part of water discharged from a nitration aerating filter are introduced into a denitrification filter for denitrification; aerobiotic nitration, wherein water discharged from the denitrification filter is introduced into a nitration aerating filter for nitration; filtration, wherein part of water discharged from the nitration aerating filter is introduced into a filtering device for filtration. The invention further provides a sewage treatment device adopting the method. The sewage treatment device comprises a regulating reservoir, a pipeline mixer, a baffle flocculation reaction tank, an oblique plate settling tank, a denitrification filter, a nitration aerating filter and a clear water pond which are connected in series, wherein a water outlet pipeline of the clear water pond is connected to a filter device.

Included are food packaging materials and processes that are useful for commercial products to extend the freshness and preserve the integrity and shelf-life of packaged foods. Said food packaging materials utilize a low bioburden, biodegradable and / or compostable shock absorbing / cushioning nonwoven structure and some form or forms of an antimicrobial and / or antifungal agent consisting of silver or silver-based species that destroy microbes which would otherwise spoil the food. The shelf-life extension process involves silver-based antimicrobial agents that function to mitigate the spread of food spoilage pathogens when they come in contact with the said food packaging materials. Fluid absorbing or superabsorbent, capabilities may be incorporated in the structure to control excess fluids.

The present disclosure comprises antimicrobial compositions and devices comprising silver compounds that resist heat and light discoloration. In one aspect, the said compounds comprise silver and at least one s-triazine ring or moiety. In another aspect, the antimicrobial compositions are hydrogels that are effective against broad spectrum of common pathogens including MRSA and VRE and are suitable for treating human or animal wounds and burns. The methods of the present disclosure comprise treating medical and non-medical devices and articles with compositions comprising the silver compounds to impart antimicrobial property.

The present disclosure provides novel bone matrix (BM) materials, and methods for preparation and use of the demineralized bone matrix materials and compositions therefrom. The methods of preparation include the use of a closed-vessel demineralization system, as well as simple, easily reproducible process steps, and significantly shortened times for demineralization. These novel BM materials do not require the inclusion of carriers and / or delivery agents, or the addition of binders, and can be made in various forms, including a clay, putty, crush, powder, or gel. The novel BM compositions and methods disclosed herein may, illustratively, have applications in the medical field, such as in surgical bone graft applications, in the repair and / or regeneration of bone and bone-related tissue, and the like.

The present invention belongs to the field of pharmaceutical industry and relates to a solid pharmaceutical composition comprising androgen receptor antagonists, e.g. Enzalutamide or ARN-509, as well as to processes for preparing the same. The solid pharmaceutical compositions are useful in the treatment of prostate cancer.

The present disclosure provides novel bone matrix (BM) materials, and methods for preparation and use of the demineralized bone matrix materials and compositions therefrom. The methods of preparation include the use of a closed-vessel demineralization system, as well as simple, easily reproducible process steps, and significantly shortened times for demineralization. These novel BM materials do not require the inclusion of carriers and / or delivery agents, or the addition of binders, and can be made in various forms, including a clay, putty, crush, powder, or gel. The novel BM compositions and methods disclosed herein may, illustratively, have applications in the medical field, such as in surgical bone graft applications, in the repair and / or regeneration of bone and bone-related tissue, and the like.

The invention discloses a carbon and nitrogen removal device for waste water with high ammonia nitrogen and high organic matter, which comprises an anaerobic fermentation tank, a high DO decomposition tank, a medium DO nitrification tank, a denitrification filter tank, a sedimentation tank and a disinfection tank connected in sequence; The top of the oxygen fermentation tank communicates with the bottom of the denitrification filter; the bottoms of the anaerobic fermentation tank, high DO decomposition tank, medium DO nitrification tank and sedimentation tank are all equipped with mud discharge ports, and each mud discharge port is connected to the denitrification tank through the mud discharge pipe respectively. The mud storage tank is connected; the mud discharge port of the mud storage tank is connected with the sludge hydrolysis tank, and the sludge hydrolysis tank is connected with the denitrification filter tank. The beneficial effects of the present invention are: the use of anaerobic fermentation to treat the original wastewater not only improves the biodegradability of the wastewater, but also reduces the biological load of subsequent treatment; the process of removing COD and the nitrification process can be separated to avoid the excessive organic load on the nitrification reaction Inhibition; the methane produced by anaerobic fermentation and the hydrolyzate of excess sludge are used as denitrification carbon sources, which not only saves operating costs, but also contributes to energy conservation and emission reduction.