The invention provides a production process for anti-adhesive soft capsules, which includes glue for making capsules, an anti-adhesive combination liquid for anti-adhesive treatment of capsules, and the components and proportions of the glue are based on the weight of the gelatin that each component accounts for. The ratio is 100% gelatin, 40-50% glycerin, 5-15% sorbitol liquid, and 95-100% purified water. The process steps include step 1, gelatinization: gelatin, glycerin, sorbitol liquid, purified water, etc. are dissolved in a certain proportion to make glue for pressing pills; step 2, ingredients: configure the contents according to the formula ratio, suspend The soft capsule should pay attention to the fineness, solid content, viscosity and fluidity of the material when batching the soft capsule, and grind it through a bead mill if necessary; step 3, press the pill to shape: press the soft capsule through the soft capsule pill machine, enter Shaping tumbler cage is carried out preliminary shaping and drying; Step 4, drying, spraying anti-adhesion composition liquid: wrapping anti-adhesion composition liquid on the rubber outer surface of soft capsule; Step 5, picking pills. It can effectively solve the production technical problem that soft capsules are prone to sticking.