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A kind of anti-adhesion soft capsule production process and anti-adhesion combination liquid

An anti-adhesion, soft capsule technology, applied in the direction of capsule delivery, inactive components of polymer compounds, inactive components of oil/fat/wax, etc. The effect of strong high temperature capability and simple operation

Active Publication Date: 2021-05-21
浙江新维士生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] In order to solve the sticking problem of soft capsules in the existing production technology, the present invention provides a soft capsule anti-sticking combination liquid and its production process, which can effectively solve the production technical problem that soft capsules are prone to sticking

Method used

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  • A kind of anti-adhesion soft capsule production process and anti-adhesion combination liquid
  • A kind of anti-adhesion soft capsule production process and anti-adhesion combination liquid
  • A kind of anti-adhesion soft capsule production process and anti-adhesion combination liquid

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0053] The embodiment of the present invention provides the specific implementation of soft capsule anti-bonding production technology, and the steps are as follows:

[0054] 1. Prepare 1020g of anti-adhesive combination liquid, which includes 1000g of soft capsule rubber lubricating oil and 20g of anti-adhesive combination wax;

[0055] 2. Put the transparent paraffin oil balls directly into the anti-adhesive combination solution, stir for 10 seconds, take them out, and dry the balls with an oil-absorbing cloth.

[0056] 3. The paraffin oil balls obtained in Example 1 were carried out to the soft capsule binding test, and the results are shown in Table 1.

Embodiment 2

[0058] The embodiment of the present invention provides the specific implementation of soft capsule anti-bonding production technology, and the steps are as follows:

[0059] 1. Prepare 1030g of anti-adhesive combination liquid, which includes 1000g of soft capsule rubber lubricating oil and 30g of anti-adhesive combination wax;

[0060] 2. Put the transparent paraffin oil balls directly into the anti-adhesive combination solution, stir for 10 seconds, take them out, and dry the balls with an oil-absorbing cloth.

[0061] 3. The paraffin oil balls obtained in Example 2 were subjected to a soft capsule binding test, and the results are shown in Table 1.

Embodiment 3

[0063] The embodiment of the present invention provides the specific implementation of soft capsule anti-bonding production technology, and the steps are as follows:

[0064] 1. Prepare 1035g of anti-adhesive combination liquid, which includes 1000g of soft capsule rubber lubricating oil and 35g of anti-adhesive combination wax;

[0065] 2. Put the transparent paraffin oil balls directly into the anti-adhesive combination solution, stir for 10 seconds, take them out, and dry the balls with an oil-absorbing cloth.

[0066] 3. The paraffin oil balls obtained in Example 3 were subjected to a soft capsule binding test, and the results are shown in Table 1.

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Abstract

The invention provides a production process for anti-adhesive soft capsules, which includes glue for making capsules, an anti-adhesive combination liquid for anti-adhesive treatment of capsules, and the components and proportions of the glue are based on the weight of the gelatin that each component accounts for. The ratio is 100% gelatin, 40-50% glycerin, 5-15% sorbitol liquid, and 95-100% purified water. The process steps include step 1, gelatinization: gelatin, glycerin, sorbitol liquid, purified water, etc. are dissolved in a certain proportion to make glue for pressing pills; step 2, ingredients: configure the contents according to the formula ratio, suspend The soft capsule should pay attention to the fineness, solid content, viscosity and fluidity of the material when batching the soft capsule, and grind it through a bead mill if necessary; step 3, press the pill to shape: press the soft capsule through the soft capsule pill machine, enter Shaping tumbler cage is carried out preliminary shaping and drying; Step 4, drying, spraying anti-adhesion composition liquid: wrapping anti-adhesion composition liquid on the rubber outer surface of soft capsule; Step 5, picking pills. It can effectively solve the production technical problem that soft capsules are prone to sticking.

Description

technical field [0001] The invention relates to the technical field of soft capsule production technology, in particular to an anti-adhesion soft capsule production technology and an anti-adhesion combination liquid. Background technique [0002] Soft capsule refers to sealing a certain amount of material liquid in a soft capsule material. The soft capsule material, namely the rubber, is made of gelatin, glycerin and purified water; The moisture accumulated on the surface is sticky, which makes the soft capsules stick to each other; when the produced product is kept in an environment above 30°C for a period of time, it will stick to a block and is not easy to shake. With the extension of storage time, The degree of bonding is more serious, forming clumps that cannot be broken up, resulting in deformation and rupture of the balls, so that the product cannot be eaten normally. [0003] Therefore, it is necessary to develop a soft capsule anti-bonding production technology to ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K9/48A61K47/42A61K47/06A61K47/14A61K47/24A61K47/44A61J3/07
CPCA61J3/078A61K9/4816A61K9/4825A61K9/4833A61K47/06A61K47/14A61K47/24A61K47/44
Inventor 凌海源蔡振保宋吕春李新平杨金山
Owner 浙江新维士生物科技有限公司
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