The invention discloses an original skin lotion. The original skin lotion is prepared from 0.015-0.025 wt% of protease, 0.01-0.03 wt% of protease dextran and the balance water. The whole original skinlotion formula abandons existing complex and multifunctional formulas, the concise formula fitting the original skin is embodied, hydrosolvent is matched with protease and protease dextran to condition the skin together, the cuticle is conditioned easily without greasy feeling, an amino acid derivative film is formed on the skin surface layer by protease, protease dextran improves skin water circulation activity, effective moisture preservation and water replenishing of the skin net structure are ensured, the dry skin is effectively moistened, the skin is kept wet and smooth, the original skin lotion helps to metabolize epidermis old cells, aging cell accumulation is reduced, skin metabolism is promoted, and the skin is activated.