A high-performance sand mist-containing sealing layer material and its preparation method belong to the road engineering technical field, and the material composition includes zwitterionic emulsified asphalt, suspension thickener, viscosity-increasing and toughening agent, film-forming agent, suspending agent, and preservative and anti-skid fine sand; the preparation method includes preparing a base material, preparing a concentrated solution of a sand-mist seal layer, preparing a high-performance sand-mist seal layer material and construction. The finger-drying time of the sand mist-containing sealing layer material obtained in the present invention is 10-30 minutes, the drawing strength at 60°C is 0.35-1.1 MPa, and the wet wheel abrasion value is 22.8-56 g / m 2 , Corundum 7 days of uniform suspension, service life of more than 3 years. The high-temperature drawing strength of the present invention is at least 20% higher than the existing traditional sand mist-containing sealing layer materials, which can solve the problems of poor high-temperature adhesion and poor wear resistance of existing materials, and has the advantages of short drying time, good maintenance effect, and easy to use. Long life and other advantages.