The invention relates to the technical field of fragrant medicinal drugs, in particular to fragrant medicinal drug beads capable of releasing high-concentration negative ions and a preparation methodthereof. The fragrant medicinal bead capable of releasing the high-concentration negative ions comprises 5-10% of a negative ion material, 10-20% of spices and 35-70% of a cosolvent; the negative ionmaterial comprises one or more of a nanometer natural ore material and a nanometer photocatalyst material; and the spices comprise one or more of rhizoma atractylodis, agastache rugosus, radix puerariae, tuber fleeceflower stem, benzoin, mentha haplocalyx, sandalwood, eupatorium fortunei, thyme, rhizoma zingiberis, ligusticum wallichii, rosemary, thuja sutchuenensis, veronicastrum sibiricum, caulis spatholobi and dalbergia odorifera, and the fragrant medicinal beads can release more than 1000 / cm<3> negative ions. The negative ion material and the perfume can be used as a product filling substance, metabolism of a human body can be effectively promoted, the vital capacity of the human body is improved, the human fatigue is eliminated, channels and collaterals are dredged, human immunity isimproved, the fragrance of the fragrant medicinal beads is more fragrant, the effects of air purification, peculiar smell removal and sterilization can be achieved, the human body is in the natural environment, and the health and sanitation of the home environment are effectively guaranteed.