The present invention provides a Xiao's biological nutrition honey (hereinafter Xiao's honey) and a method for the preparation thereof. The main material of the Xiao's honey of the invention is honey, meanwhile, served with haw, wolfberry fruit, tangerine peel, Chinese yam or other material having the same resistance; the preparing method includes following steps: soaking and cleaning haw, wolfberry fruit and Chinese yam, dried cooking after being mixed in proportion, mixing the materials after being dry cooking and the honey after being heated hotly, adding tangerine peel, sealing, and allowing the resulting system to stand, then filtering and packaging. The Xiao's honey of the invention retains the effect component of Chinese medicine which includes, but does not limit to haw, wolfberry fruit, tangerine peel, Chinese yam, the plants having different effect formula, which can be used as medicine and food, and are fully mixed in honey by the fermentation process, and the health care drinks in series having different effects are prepared. The core technology has wide application, not only provides new direction for the new health care food, but also screens high throughput activity for the activity compound after being extracted and separated by utilizing the special fermentation product by pharmaceutical enterprise, so as to develop an innovative medicine which has independent intellectual property. Meanwhile, the Xiao's honey of the invention is used as food additive which is applied in cosmetic, brewing, cigarette, tea making, biological preservation and the like, enhancing the product quality in different degree, developing new product to enhance market competitive power of the product, having great economic effect and society effect in many aspects.