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81results about How to "Delayed healing" patented technology

Electrosurgical instrument

A system and method are disclosed for removing a uterus using a fluid enclosure inserted in the peritoneal cavity of a patient so as to enclose the uterus. The fluid enclosure includes a distal open end surrounded by an adjustable loop, that can be tightened, a first proximal opening for inserting an electrosurgical instrument into the fluid enclosure, and a second proximal opening for inserting an endoscope. The loop is either a resilient band extending around the edge of the distal open end or a drawstring type of arrangement that can be tightened and released. The fluid enclosure is partially inserted into the peritoneal cavity of a patient in a deflated condition and then manipulated within the peritoneal cavity over the body and fundus of the uterus to the level of the uterocervical junction. The loop is tightened around the uterocervical junction, after which the enclosure is inflated using a conductive fluid. The loop forms a pressure seal against the uterocervical junction to contain the conductive fluid used to fill the fluid enclosure. Endoscopically inserted into the fluid enclosure is an electrosurgical instrument that is manipulated to vaporize and morcellate the fundus and body of the uterus. The fundus and body tissue that is vaporized and morcellated is then removed from the fluid enclosure through the shaft of the instrument, which includes a hollow interior that is connected to a suction pump The fundus and body are removed after the uterus has been disconnected from the tissue surrounding uterus.
Owner:GYRUS MEDICAL LTD

Biocompatible hemostatic, antiblocking, healing-promoting and surgical wound-closing modified starch material

The invention relates to a modified starch material for biocompatible hemostasis, biocompatible anti-adhesion, tissue healing promotion, absorbable surgery sealing and tissue adhesion. The invention applies biocompatible modified starch to animal tissues, wherein the modified starch material has the molecular weight of more than 15,000 daltons, and the particle diameter of between 1 and 1,000 mu m. The modified starch hemostatic material has stypticity, reduces hemorrhage, blood oozing and tissue fluid oozing of wounds, maintains relative moistening or drying of wound surfaces or the wounds, inhibits bacterium growth and inflammation reaction, and contributes to locally diminish inflammation of the wounds and relieve pain of patients. Moreover, the modified starch material can wash local parts after operation is over and remove redundant modified starch which does not participate in hemostasis, and can easily remove haemostatic under the condition of debridement treatment after self-help and first-aid treatment of war wounds; and hemostatic materials with a small amount of modified starch can be absorbed by the body, so that the pain of tearing of gauzes and bandages on people is avoided.
Owner:BEIJING UNIVERSAL LIKANG TECH CO LTD

Apparatus and methods for controlling tissue oxygenation for wound healing and promoting tissue viability

ActiveUS20090112170A1Shorten healing processLow tissue oxygenationElectrotherapyNon-adhesive dressingsTissue viabilityNon invasive
A non-invasive tissue oxygenation system for accelerating the healing of damaged tissue and to promote tissue viability is disclosed herein. The system is comprised of a lightweight portable electrochemical oxygen concentrator, a power management system, microprocessors, memory, a pressure sensing system, a temperature monitoring system, oxygen flow rate monitoring and control system, a display screen and key pad navigation controls as a means of providing continuous variably controlled low dosages of oxygen to a wound site and monitoring the healing process. A kink resistant oxygen delivery tubing, whereby the proximal end is removably connected to the device and the distal end with holes or a flexible, flat, oxygen-permeable tape is positioned on the wound bed as a means of applying oxygen to the wound site. The distal end of the tube is in communication with the electrochemical oxygen concentrator and wound monitoring system to communicate temperature and oxygen partial pressure information. A moisture absorbent dressing is positioned over the distal end of the tubing on the wound site and a reduced moisture vapor permeable dressing system is positioned whereby covering the moisture absorbent dressing, distal end of tubing and wound site creating a restricted airflow enclosure. The restricted airflow enclosure allows the out-of-the-way control and display unit to provide a controlled hyperoxia and hypoxia wound site for accelerated wound healing.
Owner:ELECTROCHEM OXYGEN CONCEPTS

Modified starch absorbable hemostasia material and preparation method thereof

The invention discloses an absorbable haemostatic material of a modified starch and a preparation method thereof. The haemostatic material is etherified modified starch or a composition which is formed by one or two or more than two of the etherified modified starch, cross-linked and composite modified starch, with a molecular weight of 15,000 to 2,000,000, a grain diameter of 10-1000Mu m and a water absorbency of 1 time to 100 times. The modified starch absorbable haemostatic material has the advantages that: the haemostatic material with biocompatibility is directly applied to bloody surface of wound to stop bleeding immediately, obviously increase the water absorbency and the water absorbing speed and have more viscosity and viscidity, thereby simultaneously blocking up damaged tissues and blood vessels while stopping bleeding. The haemostatic material is easy to swell or dissolve in water and after stopping bleeding, normal saline is used for washing to eliminate the haemostatic material not participating in stopping bleeding, thus reducing residues in the body, being beneficial to wound healing, and avoiding pains caused by unclosing pledget and bandage. The haemostatic material has the physical and chemical properties of stability, difficult decomposition, long guarantee period, convenient storage, high pressure resistance, low pressure resistance, high temperature resistance, low temperature resistance and difficult change.
Owner:BEIJING UNIVERSAL LIKANG TECH CO LTD

Device and method for treatment of wounds with nitric oxide

Topical exposure of nitric oxide gas to wounds such as chronic non-healing wounds may be beneficial in promoting healing of the wound and in preparing the wound bed for further treatment and recovery. Nitric oxide gas may be used, for example, to reduce the microbial infection and burden on these wounds, manage exudate secretion by reducing inflammation, upregulate expression of endogenous collagenase to locally debride the wound, and regulate the formation of collagen. High concentration of nitric oxide ranging from about 160 to 400 ppm may be used without inducing toxicity in the healthy cells around a wound site. Additionally, exposure to the high concentration for a first treatment period reduces the microbial burden and inflammation at the wound site and increase collagenase expression to debride necrotic tissue at the wound site. After a first treatment period with high concentration of nitric oxide, a second treatment period at a lower concentration of nitric oxide preferably ranging from about 5-20 ppm may to provided to restore the balance of nitric oxide and induce collagen expression to aid in the closure of the wound.
Owner:SENSORMEDICS +1

Biocompatibility pre-gelatinized modified starch and preparation thereof

The invention relates to a biocompatible pre-gelatinized modified starch. The water absorbency is not less than one time, and the biocompatible pre-gelatinized modified starch is taken as biocompatible hemostatic material, biocompatible anti-blocking material, biocompatible tissue-healing promoting material, biocompatible surgical sealant or biocompatible wound closure tissue glue. The invention has the advantages that the biocompatible pre-gelatinized modified starch is directly acted on the wounded area with blood for immediately stopping bleeding, has obviously increased water absorbency and speed of water absorption and greater viscosity and stickiness and further plays the role in preventing the tissue and the blood vessel from being damaged during the process of stopping bleeding; the modified starch is easy to swell or dissolve in water, and is washed by normal saline after the bleeding stopping so as to reduce the residual in the body, to be favorable for wound healing and to avoid the pain due to tearing the gauze and the bandage out; the pre-gelatinized modified starch has the actions of bacterial resistance and anti-inflammatory; and the pre-gelatinized modified starch is stable, not easy to decompose, long in guarantee period, convenient for storage, resistant at high pressure and low pressure, resistant at high temperature and low temperature and not easy to change the physicochemical characteristics.
Owner:纪欣

System for warming lower extremities of supine persons

A warming system, mounted to the foot of a bed, warms a person's lower extremities by directing air into the space between the mattress and overlaying blankets. A blower directs air into an elongated distribution chamber having many tiny exit apertures. The chamber is mounted at the foot of the bed, so that air exiting the apertures warms the person's feet. For maximum thermal transfer, the chamber is placed under the sheet and any blankets, but above the mattress cover and fitted sheet. The chamber may be implemented by a length of open cell foam, a hollow manifold with many punctures or other tiny distribution apertures, collapsible pocket, etc. While the person is lying on the bed beneath the blankets, with feet proximate the foot of the bed, the blower directs temperature-regulated air into the chamber and through the exit apertures, thereby warming the person's feet. A temperature regulator ensures a normothermic air temperature (or alternatively, hyperthermic air temperature.) Thus, the invention helps relieve or prevent “cold feet” by directing normothermic air at a person's lower extremities. Additionally, by applying heat to the feet and legs, the invention encourages blood flow by virtue of sympathetic vasodilation and local temperature-mediated vasodilation. The invention is also believed to prevent some leg and foot ulcers from forming by maintaining the lower extremity at a near normal temperature during sleep.
Owner:GEN ELECTRIC CAPITAL

Adhesive composition for carrying therapeutic agents as delivery vehicle on coatings applied to vascular grafts

Water-soluble polymeric adhesive compositions and their use as delivery vehicles for carrying therapeutic agents on implantable devices, such as vascular grafts, are disclosed. Use of drug-coated vascular grafts is demonstrated for delivery of the therapeutic agents in vivo, thereby inhibiting restenosis or neointimal hyperplasia of the vascular graft and inhibiting infection at the vascular graft site. Methods of forming the adhesive and making the coated vascular grafts are also disclosed.
Owner:UNIV OF TENNESSEE RES FOUND

Novel compositions for the treatment of wounds and skin care

InactiveUS20100284951A1Promoting natural healingAvoiding unpleasant odorBiocideOrganic active ingredientsHigh concentrationPoultice
The present invention provides novel compositions which comprise sodium hypochlorite, sodium, chloride, both organic and inorganic trace minerals in hypertonic condition presented in the forms of a clear aqueous solution (low or high concentrations for further reconstitution with purified water to obtain the final ready-to-use solution), gel or salve, lotion, wet pad, wet foam, ointment, stick, and dry mixture solution, for local application for the purposes of cleansing, disinfecting and inhibiting infection and promoting the natural healing of conditions such as fresh cuts, surgical stitches, chronic (diabetic gangrene) and acute wounds, herpes zoster, athlete's foot, and bed sores, without the necessity for covering up the wounds with gauzes / plasters nor any concurrent use of topical medication. These compositions are also suitable for the treatment of conditions such as unpleasant body odor, acne and mixed bacterial infection in the ear.
Owner:PONGPRAPANSIRI THAVISITH +2

Amnion eye drops for curing cornea alkali burn

The invention provides amnion eye drops for curing cornea alkali burn and a preparation method thereof. The preparation method comprises the steps of: taking amnion homogenate supernate as main activeconstituent; and adding with trehalose, hyaluronic acid or salt thereof, heparin or salt thereof, sodium chloride, benzalkonium bromide, vitamin, etc. The eye drops belongs to an ophthalmology drug delivery system, has a good lubrication function, and can provide a conglutination-resistant surface; and the drug delivery system is added with the other pharmacological active constituents, thereby being capable of increasing the viscocity of medical liquid, prolonging the residence time of the drug in eye surface, improving the bioavailability of the drug, reducing the side effect of the drug, reducing the drug irritation, and having a slow release effect. The amnion eye drops is an effective ophthalmology new drug, and has good clinic application foreground.
Owner:HARBIN MEDICAL UNIVERSITY

Method for building vascularized tissue engineering periosteum

The invention provides a method for building a vascularized tissue engineering periosteum. The method is characterized by comprising the following steps: 1, preparing a macromolecular micro / nano-fibermembrane by an electrostatic spinning method; 2, inoculating seed cells to the nano-fiber membrane, performing cultivation in vitro and performing directional induction for a period of time; 3, implanting a seed cell / nano-fiber membrane composite body subjected for in-vitro directional induction for a period of time in vivo, performing in-vivo vascularization for a period of time and then takingout to obtain the tissue engineering periosteum. By the method, the rejection reaction of an autologous tissue can be effectively reduced and the vascularization degree of the tissue engineering periosteum can be greatly increased; furthermore, the tissue engineering periosteum is vascularize in vivo in advance, so that the integration time of a blood vessel at the defect position and a blood vessel of the implanted tissue engineering periosteum can be shortened, the healing process of the bone defect is shortened, and the method has a very wide application prospect in the fields of wound healing and tissue engineering.
Owner:WUHAN UNIV

Antimicrobial compositions and methods of making the same

ActiveUS20150313912A1Maintaining its antimicrobial effectivenessBroaden applicationPowder deliveryOrganic active ingredientsMedicineMedical device
The present disclosure comprises antimicrobial compositions and devices comprising silver compounds that resist heat and light discoloration. In one aspect, the said compounds comprise silver and at least one s-triazine ring or moiety. In another aspect, the antimicrobial compositions are hydrogels that are effective against broad spectrum of common pathogens including MRSA and VRE and are suitable for treating human or animal wounds and burns. The methods of the present disclosure comprise treating medical and non-medical devices and articles with compositions comprising the silver compounds to impart antimicrobial property.
Owner:MEDICAL TECH RES

Ultra-potent composite for decontaminating hazardous chemical substances

The invention relates to an ultra-potent composite for decontaminating hazardous chemical substances, which is characterized by comprising two or more than two buffer systems, an MH-01 and the like. The composite can transform the hazardous chemical substances such as acid, alkali, oxidant, reducing agent, complexing agent, dissolving agent and the like into products harmless to human and the environment and avoid secondary damage and contamination. The composite has better advantages and potentials in the aspects of the decontamination spectrum, the decontamination valence, the safety and the like of the hazardous chemical substances in comparison with marketing products containing single corrosion resistance components, and is suitable for all the fields relevant to acid, alkali, oxidant, reducing agent, complexing agent and dissolving agent.
Owner:朱玛华

Nutraceutical treatments for diabetic and non-diabetic wound healing

In an embodiment of the present invention, a nutraceutical formula comprising a combination of chromium, zinc, berry extract, Polygonum cuspidatum extract, aloe vera, chlorophyll and L-arginine combined synergistically to reduce inflammation in mammals suffering from diabetes. In another embodiment of the present invention, a nutraceutical formula comprising a of zinc, chromium, berry extract, Polygonum cuspidatum extract, aloe vera, chlorophyll and L-arginine combined synergistically to enhance wound healing in mammals suffering from diabetes. In an alternative embodiment of the present invention, a nutraceutical formula comprising a of zinc, chromium, berry extract, Polygonum cuspidatum extractive, aloe vera, chlorophyll and L-arginine combined synergistically to reduce inflammation in mammals not suffering from diabetes. In another embodiment of the present invention, a nutraceutical formula comprising a combination of zinc, chromium, berry extract, Polygonum cuspidatum extractive, aloe vera, chlorophyll, and L-arginine combined synergistically to enhance wound healing in mammals not suffering from diabetes.
Owner:INTERHEALTH NUTRACEUTICALS

Sweet osmanthus grafting and seedling breeding method

The invention relates to the technical field of sweet osmanthus grafting and seedling breeding, in particular to a sweet osmanthus grafting and seedling breeding method. Sweet osmanthus seedlings subjected to layering serve as stock, leaf bud seedlings obtained after leaf buds are subjected to cuttage and seedling breeding serve as scions, processing and control are conducted in the breeding process of the scions and the stock, so that the content of harmless bacteria on the stock and the scions is small, influences of the harmful bacteria on the cut environment in the grafting process are avoided, and affinity of the stock and scions is improved. The sweet osmanthus seedlings subjected to layering serve as the stock, and the leaf bud seedlings obtained after the leaf buds are bred serve as the scions so that after the stock and the scions are grafted, regeneration can be conducted quickly, the speed of healing of the stock and the scions is increased, and the survival rate is increased.
Owner:那坡县誉桂农业科技有限公司

Dissection bone plate for locking wall agnail angle after acetabulum

An acetabulum posterior wall angle locking anatomic bone plate pertains to the technical field of surgical medical devices. The invention provides the acetabulum posterior wall angle locking anatomic bone plate which has small surgical incision, safe and reliable fixation and is conductive to the healing of fracture. The invention includes a plate body which is provided with screw holes, the screw holes are two rows of oblique holes, which are respectively arranged along one side of the plate body which is opposite to the edge of the acetabulum and the opposite side, the oblique included angle Alpha of the central line of the screw holes which are arranged at the one side of the plate body which is opposite to the edge of the acetabulum and the plate surface is 30 degrees to 45 degrees, and the oblique included angle Beta of the central line of the screw holes at the opposite side and the plate surface is 30 degrees to 60 degrees. The invention can make use of the self-shape to ensure the fixation of fracture to be most close to the normal structure after the reduction and fixation of the fracture. The invention has the integrity and the stability which are not possessed by the combined usage of a plurality of bone plates. The invention can reduce surgical incision, reduce the dissection of soft tissues, have less oppression on the periosteum and be more conductive to the healing of fracture. The placement and the removal are easy, and the cost is low. When a screw is screwed, the rod part of the screw can accurately avoid the acetabulum.
Owner:张英泽

Apparatus and Methods for Controlling Tissue Oxygenation for Wound Healing and Promoting Tissue Viability

A non-invasive tissue oxygenation system for accelerating the healing of damaged tissue and to promote tissue viability is disclosed herein. The system is comprised of a lightweight portable electrochemical oxygen concentrator, a power management system, microprocessors, memory, a pressure sensing system, an optional temperature monitoring system, oxygen flow rate / oxygen partial pressure monitoring and control system, a display screen and key pad navigation controls as a means of providing continuous variably controlled low dosages of oxygen to a wound site and monitoring the healing process. A kink resistant oxygen delivery tubing, whereby the proximal end is removably connected to the device and the distal end with holes or a flexible, flat, oxygen-permeable tape is positioned at or near the wound bed as a means of applying near 100% pure oxygen to the wound site. The distal end of the tube is in communication with the electrochemical oxygen concentrator and wound monitoring system to communicate oxygen partial pressure and, where appropriate, temperature information. A moisture absorbent dressing is positioned over the distal end of the tubing at the wound site and a reduced moisture vapor permeable dressing system is positioned whereby covering the moisture absorbent dressing, distal end of tubing and wound site creating a restricted or occluded airflow enclosure. The restricted airflow enclosure allows the out-of-the-way control and display unit to provide a controlled hyperoxia and hypoxia wound site for accelerated wound healing.
Owner:ELECTROCHEM OXYGEN CONCEPTS

Pharmaceutical composition with pure plant origin and application thereof

The invention provides a pharmaceutical composition with a pure plant origin and application thereof. Pharmacological studies show that the medicament can treat acne from multiple aspects and ensure that propionibacterium acnes do not generate drug resistance. Clinical experiment shows that the medicament has quick response, can cure the acne in a short time, obviously reduces the recurrence, has good safety and does not have obvious adverse reaction. Compared with single use of a tanshinone extract (such as a tanshinone capsule), the medicament reduces the dosage, improves the treatment effect and avoids the allergic reaction, such as rash, lip rash and the like. Simultaneously the quality of the medicament and the stability of the healing efficacy are ensured by effectively controlling active ingredients.
Owner:中北科技集团股份有限公司

Preparation method and application of nano chitosan

Preparation of nano chitosan in the invention almost has no chemical reaction, chitosan is mainly dissolved and dispersed, and chitosan is not dissolved in a sodium hydroxide solution, so that chitosan particles are separated out. Meanwhile, preparation conditions are mild, the safety is high, and preparation raw materials are common and nontoxic. The obtained nano chitosan is an ideal raw material for preparing artificial skin, the prepared artificial skin is soft in texture and is comfortable, the laminating performance between the prepared artificial skin and a wound surface is good, and the prepared artificial skin is breathable, can absorb water, has antibacterial and anti-inflammatory effects, and has the functions of stopping pain, arresting bleeding and promoting wound healing. Along with the healing of the wound of a patient and the growth of the skin of the patient, the chitosan artificial skin can be automatically dissolved and absorbed by the body, scraps cannot be left so as to avoid the delay of wound healing, and skin regeneration can be promoted. Moreover, the operation is simple, the safety is improved, and preparation processes are simplified. Required instruments are relatively common so as to be favorable for reducing the cost, and thus the nano chitosan has important application value in the field of artificial skin.
Owner:SHANDONG ANTE BIOTECH CO LTD

Nutraceutical Treatments for Diabetic and Non-Diabetic Wound Healing

In an embodiment of the present invention, a nutraceutical formula comprising a combination of two or more substances from the group: berry extract, chromium, zinc, trans-resveratrol, l-arginine, chlorophyll, vitamin C and aloe vera combined synergistically to reduce inflammation in mammals suffering from diabetes. In another embodiment of the present invention, a nutraceutical formula comprising a combination of two or more substances from the group: berry extract, chromium, zinc, fr-απs-resveratrol, l-arginine, chlorophyll, vitamin C and aloe vera combined synergistically to enhance wound healing in mammals suffering from diabetes. In an alternative embodiment of the present invention, a nutraceutical formula comprising a combination of two or more substances from the group: berry extract, chromium, zinc, trans-resveratrol, l-arginine, chlorophyll, vitamin C and aloe vera combined synergistically to reduce inflammation in mammals not suffering from diabetes. In another embodiment of the present invention, a nutraceutical formula comprising a combination of two or more substances from the group: berry extract, chromium, zinc, trans-resveratrol, l-arginine, chlorophyll, vitamin C and aloe vera, combined synergistically to enhance wound healing in mammals not suffering from diabetes.
Owner:INTERHEALTH NUTRACEUTICALS

Dressing for repairing wound surface and preparing method thereof

The invention relates to a dressing for repairing a wound surface and a preparing method thereof. The dressing comprises a non-woven fabric layer, a keratin layer and a pressure-sensitive adhesive layer, the keratin layer and the pressure-sensitive adhesive layer are both arranged on the non-woven fabric layer, and the pressure-sensitive adhesive layer is arranged on the periphery of the keratin layer and fixedly connected with the keratin layer. Keratin is arranged in the keratin layer and is hair keratin, and the hair keratin is any one of granular hair keratin and gelation hair keratin. The dressing and the preparing method have the advantages that the hemostatic effect is good, and repairing of the wound surface can be effectively accelerated; bacterial infection can be effectively prevented; good biocompatibility is achieved; oozing of the wound surface is controlled and absorbed; air permeability is high; regenerated tissue is protected; toxic and side effects are avoided, and irritability is avoided; utilization is convenient.
Owner:北京东方艾美生物技术股份有限公司

Preparation method for hair keratin-cell tissue composite engineered dressing

The invention relates to a preparation method for a hair keratin-cell tissue composite engineered dressing. The preparation method comprises the following steps: preparation of hair keratin; preparation of a cell suspension; and preparation of the dressing. The engineered dressing provided by the invention is a wound covering material with excellent effect, is capable of efficiently preventing bacterial infection, accelerating wound healing and has the advantages of good biocompatibility, capacity of controlling and absorbing exudates from wounds and allowing permeation of gas and water vapor, good air permeability, protection effect on newborn tissue, no toxic and side effect, etc. More importantly, the engineered dressing can be dissolved and absorbed by the body, so considerable bleeding and pains of patients during removing of the engineered dressing are avoided, no scrap is left to delay wound healing, and an environment beneficial for wound healing is provided for promotion of skin regeneration.
Owner:北京东方艾美生物技术股份有限公司
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