A
system and method for imaging of a sample, e.g., biological sample, are provided. In particular, at least one source electro-magnetic
radiation forwarded to the sample and a reference may be generated. A plurality of detectors may be used, at least one of the detectors capable of detecting a
signal associated with a combination of at least one first electro-magnetic
radiation received from the sample and at least one second electro-magnetic
radiation received from the reference. At least one particular
detector may have a particular electrical integration time, and can receive at least a portion of the
signal for a
time duration which has a first portion with a first
power level greater than a predetermined threshold and a second portion immediately preceding or following the first portion. The second portion may have a second
power level that is less than the predetermined threshold, and extends for a time period which may be, e.g., approximately more than 10% of the particular electrical integration time.