486results about How to "Accelerated destruction" patented technology

Ultrasound catheter devices and methods provide enhanced disruption of blood vessel obstructions. Generally, ultrasound catheters include an elongate flexible catheter body with one or more lumens, an ultrasound transmission member extending longitudinally through the catheter body lumen and a distal head coupled with the transmission member and positioned adjacent the distal end of the catheter body for disrupting occlusions. Improved features of ultrasound catheters include prevention of independent rotation of the ultrasound transmission member, a safety anchor for the distal head, a one-piece transmission member / distal head and the like.

Ultrasound catheter devices and methods provide enhanced disruption of blood vessel obstructions. Ultrasound catheter devices generally include an elongate flexible catheter body with one or more lumens, an ultrasound transmission member extending longitudinally through the catheter body lumen and a distal head coupled with the transmission member and positioned adjacent the distal end of the catheter body for disrupting occlusions. Improved features of ultrasound catheters include catheter bodies and ultrasound transmission members with increasing distal flexibility, guidewire tubes allowing contact between a guidewire and an ultrasound transmission member, distal heads with improved guidewire lumens, and torquable proximal housings for enhancing disruption of blood vessel occlusions.

A method and apparatus for disinfection / pasteurization of fluids. There is provided a mercury / gallium metal halide ultraviolet lamp enclosed within an ozone free metallic doped quartz envelope, an ozone free, metallic doped quartz enclosure for the lamp, an in-line stationary spiral or internal thread of single or multiple leads surrounding the enclosure, and a containment vessel having an inlet, an outlet and a chamber in fluid communication therewith defining a flow path for fluid to be disinfected / pasteurized. The lamp is operated at a wavelength range from about 100 nanometers to about 400 nanometers to introduce multiband ultraviolet radiation and minimal heat into the fluid with the enclosure preventing build up of ozone.

Ultrasound catheter devices and methods provide enhanced disruption of blood vessel obstructions. Generally, ultrasound catheters include an elongate flexible catheter body with one or more lumens, an ultrasound transmission member extending longitudinally through the catheter body lumen and, in some embodiments, a guidewire tube extending through the lumen. A distal head for disrupting occlusions is coupled with the distal end of the ultrasound transmission member and is positioned adjacent the distal end of the catheter body. Some embodiments include improved features such as a bend in the catheter body for enhancing positioning and / or advancement of the catheter.

Disclosed are new phosphatidylserine binding constructs with surprising combinations of properties, and a range of diagnostic and therapeutic conjugates thereof. The new constructs effectively bind phosphatidylserine targets in disease and enhance their destruction, and can also specifically deliver attached imaging or therapeutic agents to the disease site. Also disclosed are methods of using the new construct compositions, therapeutic conjugates and combinations thereof in tumor vasculature targeting, cancer diagnosis and treatment, and for treating viral infections and other diseases.

The gas pumping out method during mining cliff features that during mining cliff, the desorbed gas from the mined and released coal layers to the 'annular crack circle' via crack channel formed through mining is pumped via the drilled holes or tunnel in the 'annular crack circle'. The 'annular crack circle' is located in the stratafugic crack band over the stoped out cliff inbreak band near return airway and intake airway in the coal mining face. The present invention solves the problem of overrunning gas in stoping working face to ensure safe production.

A camouflage system to be used for both military uniforms and equipment. The system includes specialized means of printing the camouflage system unto fabric. The system can also be used for civilian applications, particularly with sportsman hunters. The system provides camouflage in both the human visible light range and the infrared. The system depends on the use of a macro-pattern resulting from a repeat of a micro-pattern. When applied to fabric, a polyamide-cotton fiber blend has a macro pattern resulting from a repeat of a micro pattern printed on at least one surface. The coloring system used comprises at least four colorings from dyes that in combination produce a percent reflectance value comparable to the negative space of the surroundings near the camouflaged subject. The system functions by a macro pattern being disruptive of the shape of the subject and a micro pattern comprising sharp edge units of a size capable of blending the subject into the background. The relative lightness values and percentages of total pattern are sufficient to produce a percent reflectance of acceptable colors, wet or dry in terms of lightness values compared to current military four-color camouflage. On fabric, the results are achieved by printing A macro pattern that disrupts the sensed shape and a micro pattern with a repeat size that produces the macro pattern. The reflectance of the material is comparable to the negative space surrounding a subject so the subject does not appear too dark or too light (out of place). The variation in the lightness between wet and dry is not greater than 17-28%, achieved during the printing process.

The invention provides for microneedle devices for delivering agents across biological barriers. The microneedles include agent reservoirs integrated into the bodies of the microneedles, themselves.

Disclosed are methods of making a genetically modified immune cell for modifying a tumor microenvironment (TME) and methods of modifying a tumor microenvironment (TME). In some embodiments, the method can include delivering a first vector to an immune cell, wherein the first vector comprises a nucleic acid encoding a protein that induces T-cell proliferation, promotes persistence and activation of endogenous or adoptively transferred NK or T cells and / or induces production of an interleukin, an interferon, a PD-1 checkpoint binding protein, HMGB1, MyD88, a cytokine or a chemokine. Methods of modulating the suppression of the immune response in a tumor microenvironment, minimizing the proliferation of tumor and suppressive cells, and increasing the efficiency of an anti-cancer therapy, anti-infection therapy, antibacterial therapy, anti-viral therapy, or anti-tumoral therapy are also provided.

Ultrasound catheter devices and methods provide enhanced disruption of blood vessel obstructions. Generally, an ultrasound catheter includes an elongate flexible catheter body with one or more lumens. An ultrasound transmission member or wire extends longitudinally through the catheter body lumen and, in many embodiments, a guide wire tube also extends through the same lumen. A distal head is fixed to or otherwise mechanically coupled with the distal end of the ultrasound transmission member or wire and is positioned adjacent the distal end of the catheter body. Although the distal end of the catheter body overlaps the distal head, the distal head is not directly affixed to the distal end of the catheter body. Thus, the distal tip may move freely, relative to the distal end of the catheter body when ultrasonic energy is applied through the ultrasound transmission member. Such a freely floating distal head enhances the efficiency of an ultrasound catheter, enabling the catheter to ablate calcific occlusions and increasing the useful life of the ultrasound transmission member and catheter.

Ultrasound catheter devices and methods provide enhanced disruption of blood vessel obstructions. Generally, ultrasound catheters include an elongate flexible catheter body with one or more lumens, an ultrasound transmission member extending longitudinally through the catheter body lumen and, in some embodiments, a guidewire tube extending through the lumen. A distal head for disrupting occlusions is coupled with the distal end of the ultrasound transmission member and is positioned adjacent the distal end of the catheter body. Some embodiments include improved features such as a bend in the catheter body for enhancing positioning and / or advancement of the catheter.

The invention relates to the field of building materials, in particular to a doped all organic corrosion inhibitor for a steel bar in concrete. The corrosion inhibitor comprises the following components in percentage by weight: 5 to 30 percent of imidazoline derivative, 5 to 15 percent of organic alcohol, 0.3 to 1.5 percent of organic metal salt and 60 to 85 percent of water. During use, the corrosion inhibitor in recommended using amount is directly added into water to be dissolved and mixed, and the corresponding using amount of water when the concrete is poured is subtracted according to the proportion of the water in the components simultaneously; and the addition amount of the corrosion inhibitor is calculated in the amount of cement required by each cubic meter of concrete structure. The corrosion inhibitor can effectively reduce and slow down the corrosion of the steel bar in the concrete, reduces the damage of chloride ions to the surface passivation property of the steel bar so as to slow down the corrosion of the chloride ions to the steel bar, and can be widely applied to industrial and civil reinforced concrete buildings in offshore areas, harbors, wharfs and coastal areas.

The invention discloses a stewing process for preparing wood dissolving pulp by utilizing natural-color unbleached papermaking-grade wood pulp in a modifying way, overcoming the defect of poor reaction property of products prepared by an alkali refining method. The stewing process conditions of natural-color unbleached wood pulp in a stewing device are as follows: liquor ratio is 1:2.5-7.0; alkali charge includes 10-50% of NaOH and 0.1-50% of Na2S; a temperature increasing condition comprises the following steps of: increasing temperature to 115-130 DEG C for 30-60 minutes, and keeping the temperature for 30-120 minutes; continuously increasing the temperature to 135-150 DEG C for 30-60 minutes, and keeping the temperature for 120-180 minutes; after the temperature is kept, continuously increasing the temperature to 165-175 DEG C, and keeping the temperature for 30-180 minutes; after the temperature is kept, reducing the temperature, and discharging; and stewing to end after the discharging. The wood pulp produced by the stewing process not only has higher content of alpha-celluloses, but also has good reaction property, and is suitable for filament and staple fibers.