1943results about How to "Reduce wall thickness" patented technology

A clot retrieval device (9501) for removing occlusive clot from a blood vessel comprises an inner elongate body (9503) and an outer elongate body (9504) at least partially overlying the inner elongate body (9503). The device also comprises an elongate member or shaft (9502) having a proximal end which extends exterior of a patient so that a user can retrieve the stent-basket device and captured clot by retracting the shaft (9502). The outer elongate body (9504) and the inner elongate body (9503) are connected to the distal end of the shaft (9502) and are expandable relative to the shaft (9502) from a collapsed delivery configuration to an expanded deployed configuration. The outer elongate body (9504) is expandable relative to the inner elongate body (9503) to a radial extent which is greater than the radial extent of the inner body (9503) in the deployed configuration.

A surgical device integrating a suction mechanism with a coagulation mechanism is provided for improving lesion creation capabilities. The device comprises an elongate member having an insulative covering attached about means for coagulating soft tissue. Openings through the covering expose regions of the coagulation-causing elements and are coupled to lumens in the elongate member which are routed to a vacuum source. A fluid source to passively transport fluid along the contacted soft tissue surface may be provided in order to push the maximum temperature deeper into tissue.

Ultrasound catheter devices and methods provide enhanced disruption of blood vessel obstructions. Ultrasound catheter devices generally include an elongate flexible catheter body with one or more lumens, an ultrasound transmission member extending longitudinally through the catheter body lumen and a distal head coupled with the transmission member and positioned adjacent the distal end of the catheter body for disrupting occlusions. Improved features of ultrasound catheters include catheter bodies and ultrasound transmission members with increasing distal flexibility, guidewire tubes allowing contact between a guidewire and an ultrasound transmission member, distal heads with improved guidewire lumens, and torquable proximal housings for enhancing disruption of blood vessel occlusions.

A system for percutaneously inserting a prosthesis containing a biological replacement for a defective valve into an implantation site through a body lumen. The system contains a balloon catheter upon which a collapsable stent containing a venous valvular replacement is mounted. A protective shield is slidably mounted upon the catheter that is movable between a closed position over the balloon and an open position wherein the balloon can be inflated to expand the stent. A central lumen runs through the catheter that is formed of stainless steel. The central lumen provides a one to one torque ratio between the proximal end of the catheter and the distal end to enhance the steerability of the catheter. The vein of the replacement is reduced in thickness between 50% and 90% of its original size thereby considerably reducing the size of the replacement package when the stem is collapsed upon the balloon of the catheter.

A catheter assembly is provided having an inner member and an outer member extending along a longitudinal axis, the inner member and the outer member having a coaxial configuration and dimensioned for relative axial movement. The outer member may include an anti rotation member adapted to engage with a longitudinal slot formed on the inner member so as to maintain rotational alignment between inner member and outer member. The inner member can be made with a proximal portion made from a tubing such as hypotubing or a coil tubing. The inner member also may be made with a proximal portion made with a support mandrel. A coil tubing can be utilized to form the guide wire receiving member which is attached to the inner member.

A floodback detector for refrigerant systems employing any of: minimum suction temperature, temperature rate of change and duration thereof; minimum superheat, superheat rate of change and duration thereof.

A clot retrieval device (9501) for removing occlusive clot from a blood vessel comprises an inner elongate body (9503) and an outer elongate body (9504) at least partially overlying the inner elongate body (9503). The device also comprises an elongate member or shaft (9502) having a proximal end which extends exterior of a patient so that a user can retrieve the stent-basket device and captured clot by retracting the shaft (9502). The outer elongate body (9504) and the inner elongate body (9503) are connected to the distal end of the shaft (9502) and are expandable relative to the shaft (9502) from a collapsed delivery configuration to an expanded deployed configuration. The outer elongate body (9504) is expandable relative to the inner elongate body (9503) to a radial extent which is greater than the radial extent of the inner body (9503) in the deployed configuration. The stent-basket construction of the device creates a reception space (9507) between the inner (9503) and outer (9504) to receive the target clot. The outer body (9504) is configured to allow as much as possible of the clot to migrate through it into the internal reception space (9507). Housing the clot in this reception space rather than pinning it to the wall of the vessel means that the clot is under less compression and can thus be retracted at a lower force. The inner elongate body (9503) and a distal capture net (9505) protect the distal vascular bed from embolisation.

Apparatus and methods for stenting are provided comprising a stent attached to a porous biocompatible material that is permeable to endothelial cell ingrowth, but impermeable to release of emboli of predetermined size. Preferred stent designs are provided, as well as preferred manufacturing techniques. Apparatus and methods are also provided for use at a vessel branching. Moreover, embodiments of the present invention may comprise a coating configured for localized delivery of therapeutic agents. Embodiments of the present invention are expected to provide enhanced embolic protection, improved force distribution, and improved recrossability, while reducing a risk of restenosis and thrombus formation.

A syringe includes a body having a distal end, a proximal end and a center section therebetween. The distal end of the syringe body includes a conical portion that extends and tapers from the center section to an injection neck forming a discharge outlet. The proximal end of the syringe body includes a radial expansion section and an outward extending lip. An inner diameter of the radial expansion section is larger than an inner diameter of the center section and the outer diameter of the radial expansion section is smaller than an outer diameter of the center section. A plunger is movably disposed in the syringe body and includes a pair of coupling members defining a slot therebetween, the plunger being substantially seated in the radial expansion section in a pre-use state of the syringe. An alignment flange is formed on the conical portion and extends the distance between the center section and the injection neck. The alignment flange defines an internal hollow area therein in fluid communication with the interior of the syringe body, which is adapted to collect air bubbles that are present within the interior of the syringe body.

Balloon catheters having the strength and maximum inflated diameter characteristics of an angioplasty balloon and having the recovery characteristics during deflation of an elastic embolectomy balloon. The balloon catheter can be made in very small sizes and has a lubricious and chemically inert outer surface. The balloon catheter is easy to navigate through tortuous passageways, is capable of rapid inflation and deflation and has high burst strengths. Balloon covers having these same characteristics are also described for use with conventional embolectomy balloons or angioplasty balloons.

The present invention relates to a balloon portion for a balloon catheter for radially expanding a vessel in the body of a mammal, which catheter comprises a tube portion with a passage therethrough and a hollow expandable balloon portion defined by a fluid impervious wall and secured to the tube portion, which balloon portion can be inflated and deflated by means of a fluid passed through the passage, characterized in that:a. the wall of the balloon portion is formed from a flexible substantially fluid impervious material having reinforcing fibers formed integrally with the wall material; andb. the balloon portion is preformed to the desired radial diameter at its inflated state having smaller diameter end portions and a wider diameter portion intermediate the said ends and has a substantially uniform wall thickness.The invention also provides a balloon catheter in which the balloon portion is a balloon of the invention. The invention further provides a method for making the balloon catheter of the invention.

This is in the general field of surgical instruments and is specifically a delivery catheter with a flexible, proximally-manipulated hinge or joint region. The inventive catheter may have a balloon region. The catheter may have a shaft of varying flexibility which contains several lumen. The inner, or delivery, lumen generally may be used with a guidewire to access target sites within the body via the flexible, small diameter vessels of the body. The delivery lumen may be also used for placement of occlusive materials, e.g., in an aneurysm. Inflation of the micro-balloon, located near the distal tip of the catheter, is effected using the inflation lumen. The push / pull wire lumen contains a wire, which when manipulated, flexes the catheter's distal tip. The push / pull wire tubing may have a variable thickness to aid in adjusting the degree of flexibility. Moreover, the delivery catheter may be capable of twisting in a helical or corkscrew-like manner for traversing certain vasculature. This may be accomplished by winding the push / pull wire within the catheter and fixedly attaching it. The catheter may further include an entry in the catheter wall to allow for the insertion of a guidewire; this may facilitate the rapid exchange of catheter devices as desired by the user.

This is in the general field of surgical instruments and is specifically a delivery catheter with a flexible, proximally-manipulated hinge or joint region. The inventive catheter may have a balloon region. The catheter may have a shaft of varying flexibility which contains several lumen. The inner, or delivery, lumen generally may be used with a guidewire to access target sites within the body via the flexible, small diameter vessels of the body. The delivery lumen may be also used for placement of occlusive materials, e.g., in an aneurysm. Inflation of the micro-balloon, located near the distal tip of the catheter, is effected using the inflation lumen. The push / pull wire lumen contains a wire, which when manipulated, flexes the catheter's distal tip. The push / pull wire tubing may have a variable thickness to aid in adjusting the degree of flexibility. Moreover, the delivery catheter may be capable of twisting in a helical or corkscrew-like manner for traversing certain vasculature. This may be accomplished by winding the push / pull wire within the catheter and fixedly attaching it. The catheter may further include an entry in the catheter wall to allow for the insertion of a guidewire; this may facilitate the rapid exchange of catheter devices as desired by the user.

A surgical device integrating a suction mechanism with a coagulation mechanism is provided for improving lesion creation capabilities. The device comprises an elongate member having an insulative covering attached about means for coagulating soft tissue. Openings through the covering expose regions of the coagulation-causing elements and are coupled to lumens in the elongate member which are routed to a vacuum source. A fluid source to passively transport fluid along the contacted soft tissue surface may be provided in order to push the maximum temperature deeper into tissue.

A surgical device integrating a suction mechanism with a coagulation mechanism is provided for improving lesion creation capabilities. The device comprises an elongate member having an insulative covering attached about means for coagulating soft tissue. Openings through the covering expose regions of the coagulation-causing elements and are coupled to lumens in the elongate member which are routed to a vacuum source. A fluid source to passively transport fluid along the contacted soft tissue surface may be provided in order to push the maximum temperature deeper into tissue.

Apparatus and methods for stenting are provided comprising a stent attached to a porous biocompatible material that is permeable to endothelial cell ingrowth, but impermeable to release of emboli of predetermined size. Preferred stent designs are provided, as well as preferred manufacturing techniques. Apparatus and methods are also provided for use at a vessel branching. Moreover, embodiments of the present invention may comprise a coating configured for localized delivery of therapeutic agents. Embodiments of the present invention are expected to provide enhanced embolic protection, improved force distribution, and improved recrossability, while reducing a risk of restenosis and thrombus formation.

Apparatus and methods for stenting are provided comprising a stent attached to a porous biocompatible material that is permeable to endothelial cell ingrowth, but impermeable to release of emboli of predetermined size. Preferred stent designs are provided, as well as preferred manufacturing techniques. Apparatus and methods are also provided for use at a vessel branching. Moreover, embodiments of the present invention may comprise a coating configured for localized delivery of therapeutic agents. Embodiments of the present invention are expected to provide enhanced embolic protection, improved force distribution, and improved recrossability, while reducing a risk of restenosis and thrombus formation.

A syringe includes a body having a distal end, a proximal end and a center section therebetween, a plunger movably disposed in the body, and a hollow alignment flange for orienting and manipulating the syringe.

Ultrasound catheter devices and methods provide enhanced disruption of blood vessel obstructions. Ultrasound catheter devices generally include an elongate flexible catheter body with one or more lumens, an ultrasound transmission member extending longitudinally through the catheter body lumen and a distal head coupled with the transmission member and positioned adjacent the distal end of the catheter body for disrupting occlusions. Improved features of ultrasound catheters include catheter bodies and ultrasound transmission members with increasing distal flexibility, guidewire tubes allowing contact between a guidewire and an ultrasound transmission member, distal heads with improved guidewire lumens, and torquable proximal housings for enhancing disruption of blood vessel occlusions.

A system for percutaneously inserting a prosthesis containing a biological replacement for a defective valve into an implantation site through a body lumen. The system contains a balloon catheter upon which a collapsable stent containing a venous valvular replacement is mounted. A protective shield is slidably mounted upon the catheter that is movable between a closed position over the balloon and an open position wherein the balloon can be inflated to expand the stent. A central lumen runs through the catheter that is formed of stainless steel. The central lumen provides a one to one torque ratio between the proximal end of the catheter and the distal end to enhance the steerability of the catheter. The vein of the replacement is reduced in thickness between 50% and 90% of its original size thereby considerably reducing the size of the replacement package when the stem is collapsed upon the balloon of the catheter.

An implantable medical device (IMD) and methods of fabricating the same are provided. An IMD can include a housing and a cofire ceramic module (CCM) coupled to the housing. The CCM can include an antenna cofire-integrated in the CCM. The antenna can include a plate composed of conductive material, and conductive antenna elements that are annular substrates having perimeters substantially coextensive with the perimeter of the plate. The antenna can also include interconnections. A first set of interconnections can be coupled between the plate and one of the conductive antenna elements, and a second set of interconnections can be coupled between the conductive antenna elements. The antenna can also include a feed line conductively coupled to the plate. In some embodiments, the feed line can be substantially serpentine-shaped to adjust impedance in the CCM.

A low swage load fastening system is provided for installing swage-type fasteners to secure a plurality of workpieces together. The fastener includes a pin member having an elongated pin shank to be located in aligned openings in the workpieces. An enlarged head at one end of the pin engages one side of the workpieces. A grooved pin portion extends past an opposite side of the workpieces. A collar includes a shank portion adapted to be swaged into the pin lock grooves in response to a relative axial swage load applied by an installation tool. As one aspect of the system, the collar is as-headed and does not require thermal processing yet provides an optimum balance of reduced collar shank wall thickness and increased hardness, whereby the swage load is minimized. A low swage load thread form for the lock grooves of the pin is also provided, a reduced diameter, relatively short pull portion pin extension, installation tool improvements, and an associated method of use are also disclosed.

The fluid injection apparatus for use with a syringe includes an injector and a pressure jacket assembly associated with the injector. The injector includes a housing defining a central opening and a drive piston extendable through the central opening for imparting motive forces to a syringe plunger disposed within the syringe. The pressure jacket assembly includes a pressure jacket and at least one support arm associated with and extending outward from the housing. A syringe retaining member is attached to the at least one support arm. The syringe-retaining member defines a syringe receiving slot for receiving at least a portion of the syringe. A light source is located on the support arm and faces the pressure jacket for illuminating the syringe. The syringe includes an alignment flange defining a bulged air bubble viewing window (see A). The alignment flange is used to properly orient the syringe in the pressure jacket.

A heart valve includes a stent for fixing the heart valve in a bodily vessel and a stentless valve portion for restricting the flow of blood through the valve to a single direction. The valve portion is supported and suspended in the bodily vessel via connectors spanning a gap between the valve portion and the stent or by a direct end-to-end connection with the anchor portion.

A method of coating a medical device is provided that includes forming a beam of ions of a coating material and focusing said beam using at least one electrostatic lens. The method also includes arranging the medical device within said beam. In the method, the forming of said beam of the coating material may include aerosolizing a solution of the coating material and evaporating a solvent of the solution. The method may include providing an opposite electrostatic charge to the medical device. The method may include fixturing the medical device to allow the coating material to contact about all of a surface of the medical device. The method may include rotating the medical device about an axis perpendicular to said beam. The method may include moving the medical device through the region of the focus of the at least one electrostatic lens and contacting said beam with a portion of an exposed surface of the medical device. A system for coating a medical device is provided. A medical device having a coating applied by a method is provided.

The invention described relates to a composition for a multilayer tube having an inner and an outer layer. Preferably the inner layer of the tube has at least one at least partially crosslinked, preferably polyethylene, which is less flexible than the adjacent more flexible outer layer, which is preferably a thermoplastic elastomer. The inner and outer layers are typically coextruded during manufacture, with at least one overmolded end, preferably crosslinked, which generally has an internal diameter which is essentially the same as the internal diameter of the multilayer tube. The multilayer tube is typically crosslinked, preferably by electron beam.

A catheter balloon and method involves extruded tubing with multiple layers of different durometer values, selected such that the blow up ratio (BUR) at the balloon's inner surface is increased. In one method a two stage blow mold process uses a small radius initial stage where radial growth is limited, followed by a second stage to a final dimension. A single stage blow mold process is also disclosed where the materials and processing are selected to approach the elongation to failure limit of the material. The single stage approach is preferably followed by a modified post-expansion heat set treatment to promote greater axial strength, leading to a preferred failure mode in the axial rather than radial direction.

A catheter having an elongated shaft and a balloon on a distal shaft section, the elongated shaft comprising an outer tubular member, and an inner tubular member which has a bonded portion along which an outer surface of the inner tubular member is bonded to an inner surface of the outer tubular member. The inner tubular member has a proximal portion proximal to the bonded portion, and a distal portion distal to the bonded portion with higher axial compression stiffness and column strength than the proximal portion thereof. The catheter has improved traceability, axial collapse resistance, pushability, and crossability, for improved ability to position the balloon at a desired location in a patient's body lumen.