68 results about "Transplantation surgery" patented technology

The present invention relates to an apparatus for automated hair transplantation through the well-known extraction technique of capillary units or FUE, comprising the morphological analysis of hair follicles in real-time by means of artificial vision, mapping of points for extraction and implant, simulation of the final result, a system of local anaesthesia, global, simultaneous or in sequential phases, at least one articulated mechanical arm associated with a tool for differentially extracting and implanting hair follicles.The present invention is useful to reduce the time and cost associated with the intervention, improve the quality of the operation and the final result, in terms of capillary density, contemplating the study of cell differentiation of follicles with the required estimate of time required regarding the growth. Minimizes the positional discomfort of the patient, the pain associated with the administration of anaesthesia, among other inconveniences usually experienced by the patient in this type of intervention. The present invention is useful for diagnosis, treatment and hair transplantation procedures.

Improved methods for heart transplant are described. The methods utilize an allograft comprising a layer of amnion to improve the performance and reduce complications of the heart transplant surgery and the allograft has a pre-made size and shape suitable for the application.

A method for computer-assisted planning of a transplant surgery is provided. The method includes obtaining a computer-readable representation of a donor and recipient skeletal fragment; determining surgical cutting planes on the computer-readable representation of the donor skeletal fragment from which a portion of the donor skeletal fragment from the computer-readable representation of the donor skeletal fragment will be harvested; determining virtual cutting guides; performing a virtual osteotomy to separate the portion of the donor skeletal fragment from the computer-readable representation of the donor skeletal fragment from a remainder portion of the donor skeletal fragment based on a position of the virtual cutting guides that are attached to the computer-readable representation of the donor skeletal fragment; positioning the donor skeletal fragment within a transplant region of the recipient skeletal fragment; and creating a hybrid computer-readable representation comprising the recipient skeletal fragment and the portion of the donor skeletal.

The invention discloses an operation mechanism for an ophthalmic corneal transplantation surgical robot. The operation mechanism includes two bases arranged beside an operating table, two robotic armsrespectively fixed on vertical lifting platforms of the bases, at least two instrument-holding arms to simulate the hands of a surgeon and a mirror-holding arm to place imaging equipment; each instrument-holding arm includes a preoperative positioning mechanism and an intraoperative instrument-manipulating mechanism; the preoperative positioning mechanism is used for positioning the intraoperative instrument-manipulating mechanism; the intraoperative instrument-manipulating mechanism includes a position adjusting mechanism and a pose adjusting mechanism; the position adjusting mechanism can realize the position adjusting of the pose adjusting mechanism in space; and the motion and force transmission of the pose adjusting mechanism can be achieved through a rope-pulley mechanism so as to control tools to perform operations. Through the operation mechanism, the movement track of operation tools at any position and pose in a working space can be realized, and corneal drilling and suturing during corneal transplantation can be accomplished; and the operation mechanism is good in flexibility, high in precision, high in motion stiffness and large in motion space range.

The embodiment of the invention discloses a multifunctional hair follicle transplanting instrument. The machine includes a drilling and fetching mechanism, a hair follicle clamping / cutting mechanism and a hair follicle pushing mechanism, wherein the drilling and fetching mechanism consists of a first driving mechanism, a planting head shell in linkage with the first driving mechanism and a needle fixedly arranged on the planting head shell; the hair follicle clamping / cutting mechanism is composed of a pair of clamping pieces rotatably arranged on the planting head shell and a pushing mechanism; the needle is provided with a groove, the clamping heads of the clamping pieces are arranged inside the groove, and the pushing mechanism is used for driving the clamping pieces to rotatably clamp / cut the hair follicles; the hair follicle pushing mechanism includes a pushing needle arranged inside the needle, and the pushing needle is driven by a second driving mechanism to push. The multifunctional hair follicle transplanting instrument integrates the functions of drilling and loosening, clamping or cutting and planting hair follicles, not only can the efficiency of hair follicle transplanting operations be increased, but manpower costs of the operations are decreased, and the survival rate of the hair follicles is increased.

The invention provides an oral lip mucosa ocular surface reconstruction instrument. The oral lip mucosa ocular surface reconstruction instrument is composed of a pair of microsurgical forceps, a pair of microsurgical scissors, a microsurgical needle holder, a left-hand haemostatic clamp and a right-hand haemostatic clamp. By the adoption of the oral lip mucosa ocular surface reconstruction instrument, oral lip mucosa transplantation surgery can be safely and efficiently completed, the surgical time can be shortened by 30 to 45 minutes, and the number of surgical personnel can be reduced by one; the oral lip mucosa ocular surface reconstruction instrument is suitable for operation in a narrow space, and the surgical field can be easily exposed; the haemostatic clamps have the local pressurizing haemostatic function and the remarkable traction ectropion function, so that the surgical field is fully exposed, operation is convenient, and the mucosa tissue is not injured. The oral lip mucosa ocular surface reconstruction instrument is an oral lip mucosa surgery combined instrument which is reasonable in design, simple in structure, suitable for dedicated spaces and parts, capable of fully exposing the surgical field, particularly suitable for ophthalmology oral lip mucosa ocular surface reconstruction surgery, convenient to operate and manufacture, and capable of being applied and popularized conveniently.

The invention relates to the field of surgical instruments, and especially relates to a transfer box special for organ transplantation. The transfer box special for organ transplantation operation comprises a box body, and a sliding cavity which is arranged in the box body and is provided with an upward opening; a heat preservation block used for preventing temperature loss is arranged in the sliding cavity in a sliding mode; a circular cavity with a rightward opening is formed in the heat preservation block; a storage rack is arranged in the circular cavity in a sliding manner; first springswhich are up-down symmetrical are arranged between the storage rack and the rear side end wall of the circular cavity. The transfer box special for organ transplantation operation possesses followingadvantages: organ transfer can be conveniently realized; in equipment moving process, multiple locking can be carried out on a container for placing organs; organs are prevented from scattering in thetransferring process, meanwhile, the influence of the external environment on the organs is avoided; meanwhile, the organs can be kept horizontal all the time in the equipment moving process, large angle deviation and collision are avoided; and at the same time, a buffer device is arranged in the transfer box and can effectively absorb vibration and prevent organ damage when the transfer box falls off.

The invention relates to a cell co-culture system for promoting cartilage differentiation.The cell co-culture system is composed of synovial-derived mesenchymal stem cells and meniscus cells, the proportion of the synovial-derived mesenchymal stem cells to the meniscus cells is 1: (0.33-3), the synovial-derived mesenchymal stem cells are 2-5 -generation cells which are subjected to primary culture, and the meniscus cells are 2-5 -generation cells which are subjected to primary culture; the system can jointly form a meniscus transplantation system with demineralization cortical bone and a BMP-4-PBS solution; the invention further provides application of the cell co-culture system to meniscus transplantation of allogeneic or xenogenic animals; the cell co-culture system effectively promotes cartilage differentiation, and the success rate of meniscus transplantation surgery is raised.

The invention discloses a spreading device for the renal transplantation surgery. The device comprises a base, a push handle is arranged on the base, and an automatic retractable rod is fixedly connected to the base; a horizontal rod is connected to the upper end of the automatic retractable rod through a fixing connection block, a driving case is arranged at the left end of the horizontal rod, and two spreading plates are arranged at the lower side of the right end of the horizontal rod. The spreading device for the renal transplantation surgery is ingenious in structural arrangement and reasonable in distribution, a motor drives a first transmission rod to rotate, the first transmission rod drives a lead screw to rotate, the lead screw rotates to drive two sleeving blocks on the lead screw to be closed to or away from each other, the spreading plates are driven to be close to or away from each other accordingly, and the effect of spreading wounds is achieved. Small-sized shadowless lamps are arranged at the lower ends of the inner sides of the spreading plates, swishes are arranged at the upper ends of the spreading plates, storage batteries are arranged in the spreading plates, the small-sized shadowless lamps are connected with the switches and the storage batteries, during surgery, the further illumination effect can be achieved for surgery doctors, and the surgery can be more accurate and errorless.

A combined apparatus for the deep corneal transplantation is composed of two deep corneal matrix hooks consisting of handle and the extended rod with hook head, and a viscoelastic agent injector consisting of needle seat and tube. Its advantages are short operation time and high safety and effect.

The present invention relates to a kind of compound artificial skin with two kinds of cells implanted on its two sides and its construction process. On two sides of rack of ox collagen membrane with epidermal growth factor, fibroblast and epidermal cell are implanted, and the middle part is growing fibroblast of density grater than 1E6 / sq cm. The artificial skin has excellent physical characteristics, high strength, high flexibility, high infection resistance, no antigenicity, convenient operation transplantation and good fusion with peripheral skin after transplantation.

The invention provides a kidney surgery model capable of simulating blood circulating and urine generating functions. Compared with existing kidney simulation devices which are appearance models onlyand have the problems of being simple in structure, unitary in function, low in simulation degree and unsupportive of teaching demonstration and surgery operation, the kidney surgery model can be usedfor preclinical teaching and scientific research. The model simulating human kidney organs and parts thereof is made according to a proportion of 1:1, thereby being high in simulation level, and a relation between kidney blood circulation and urine generation can be simulated through a pulse pump, a pressure control part and a valve; parts of the model are assembled and spliced, so that the modelcan be used for clinical surgical operation and teaching demonstration, medical staff can simulate related process operations of a kidney transplanting surgery, and understanding on kidney organ andsurgical success rate of the medical staff are improved.

The present disclosure describes a system and a method for producing patient-specific small diameter vascular grafts (SDVG) for coronary artery bypass graft (CABG) surgery. In some embodiments, the method for producing SDVGs includes non-invasive quantification of patient-specific coronary and vascular physiology by applying computational fluid dynamics (CFD), rapid prototyping, and in vitro techniques to medical images and coupling the quantified patient-specific coronary and vascular physiology from the CFD to computational fluid-structure interactions and SDVG structural factors to design apatient-specific SDVG.

The invention discloses a medical implant for improving cell osteogenesis performance and a preparation method thereof. The polished and cleaned medical metal is subjected to laser processing so as toobtain a surface structure with super-hydrophilic performance, and a statin drug coating is prepared on the super-hydrophilic surface, so that the drug loading is more uniform and sufficient. The medical implant with the drug coating has the function of enhancing the osteogenesis performance of human cells, is beneficial to rapid and tight combination with human tissues after being implanted intoa human body, is beneficial to smooth implementation of a transplantation operation, and effectively avoids secondary injury caused by transplantation failure.

Minimally invasive techniques utilized in bypass grafting are disclosed. For instance, a method of implanting an end portion of a graft in the body of a patient during a bypass grafting procedure includes the steps of (i) advancing a medical instrument within a circulatory system of said body, (ii) guiding a distal end of said medical instrument out of said circulatory system through an opening defined in said circulatory system after said medical instrument advancing step, (iii) advancing said end portion of said graft within said medical instrument after said guiding step, and (iv) securing said end portion of said graft to a blood vessel of said circulatory system after said end portion advancing step.

The invention discloses an autonomous stereoscopic vision navigation method and system for a corneal transplantation surgical robot, and the method comprises the steps of obtaining the registration data of a stereoscopic microscope camera and a world coordinate system Oxyz and the calibration and correction data of the stereoscopic microscope camera, and collecting two facial images according to the stereoscopic microscope camera, and respectively taking the two facial images as a reference image R and a target image T; inputting the reference image R and the target image T into a convolutional neural network CNN for feature extraction, capturing and updating three-dimensional information of a target object and pose information of a surgical tool in real time, and obtaining the reference image R and the target image T through a deep learning method to complete vision sensing information of autonomous stereoscopic vision navigation; and controlling the corneal transplantation surgical robot to perform autonomous stereoscopic visual navigation on corneal transplantation surgical suture needle insertion and suture knotting by utilizing visual sensing information.

Application for changing foreign organs into organs formed by cells of organ receivers includes preparing an animal (an organ provider) with an organ with the size identical to that of an organ of a human body (an organ receiver) at first, and then injecting antibody crosslinking substances of corresponding animal tissue stem cells to the organ of the animal or circulated blood of the animal or the organ receiver before or after organ transplantation. After transplantation surgery is successful, immunosuppressant is used according to conventional dose, and simultaneously, stem cell mobilization agent is injected. The application for changing foreign organs into organs formed by cells of organ receivers has the advantages that organ sources are sufficient, cost is low, and patients can buy suitable organs at any time without waiting for suitable organ donors, and do not need to take immunosuppressive drug during lifetime.

The invention provides an application of long-chain non-coding RNA-NEAT1, sgRNA overexpressing the RNA-NEAT1, an adeno-associated virus and an application and belongs to the technical field of medicines. The invention provides the application of long-chain non-coding RNA-NEAT1 (Ribonucleic Acid-NEAT1) to preparation of medicines for treating Fuchs' corneal endothelial malnutrition. Overexpression of the long-chain non-coding RNA-NEAT1 can effectively reduce corneal endothelial injury and relieve corneal edema symptoms, and the long-chain non-coding RNA-NEAT1 can be used for treatment of Fuchs' corneal endothelial malnutrition, operation steps and risks of treatment are greatly simplified, corneal transplantation operation is not needed, the source is sufficient, and the treatment cost is low.

The invention provides a facial autologous fat transplantation operation navigation system and a virtual scale prompting method. The system comprises a dental cast registration block, a dental cast connecting sleeve, a dental cast registration marking plate, a surgical instrument registration marking plate and an identification map, and can further comprise an intelligent terminal. The system is based on an augmented reality technology, a personalized noninvasive registration tooth socket is utilized, virtual information, namely skin, blood vessels, bones and preoperative planning, and real information, namely a patient entity are fused and superposed, a marking nail does not need to be manually implanted before an operation, and through personalized dental cast noninvasive registration, additional trauma brought to a patient by invasive implantation is avoided; and a three-dimensional model of the patient and preoperative operation planning are fused with patient entity information during the operation, surgical instruments are tracked in real time, and a pose and a needle inserting distance of an injector in a needle inserting process are reminded in real time, so that a doctor can complete the operation more accurately.

The invention discloses a distraction fixator for a kidney transplantation operation, and relates to the field of kidney transplantation operations. The distraction fixator for the kidney transplantation operation comprises a bed body, a supporting and positioning base, a lifting supporting mechanism and a distraction fixator structure, the bottom of the bed body is fixedly connected with two sets of supporting blocks, the two sets of supporting blocks are symmetrically distributed, and a reinforcing transverse plate is fixedly connected between the two sets of supporting blocks. When the distraction fixator for the kidney transplantation operation is used, the position can be adjusted according to the body position of a patient, then the rectangular frame is installed and fixed to the upper portion of the bottom supporting platform through the lifting supporting mechanism, and the position of the rectangular frame is adjusted according to the weight of the patient; and finally, the distraction arms and the distraction plates can be installed according to the incision condition of the patient, and the distance and the angle between the distraction arms and the distraction plates can be adjusted, so that the distraction effect is guaranteed.

The invention relates to the technical field of medical instruments, in particular to a continuous refrigeration system for kidney transplantation operation. The continuous refrigeration system comprises a kidney bag, a kidney bag opening, a kidney portal opening, an in-vitro ring, an in-vivo ring, a pull wire, an inner pull ring and an outer pull ring, the kidney bag opening is formed in the upper end of the kidney bag, a transplanted kidney and smoothie mixture enters the kidney bag through the kidney bag opening, the kidney portal opening is formed in the lower end of the kidney bag, the in-vitro ring is annularly arranged at the kidney bag opening and enables the kidney bag opening to be supported and expanded, the in-vivo ring is arranged on the kidney bag in an annular mode and arranged in the body of a patient of the transplanted kidney, the outer surface of the kidney bag is connected with the pull wire, the two ends of the pull wire protrude out of the kidney bag, the lower end of the pull wire is connected with the inner pull ring, and the upper end of the pull wire is connected with the outer pull ring. The kidney bag is pulled into the in-vivo kidney anastomosis position through the inner pull ring, the kidney bag is pulled out through the outer pull ring after an operation, and the problem that a kidney supply low-temperature protection bag is inconvenient to placein a human body and take out after the operation is solved.

The invention provides soft tissue-like elastic hydrogel as well as a preparation method and application of a tissue and organ model of the soft tissue-like elastic hydrogel, and belongs to the technical field of hydrogel-based tissue and organ model manufacturing. Acrylamide and an unsaturated double-bond monomer containing a negative electron group are subjected to photocuring to form a covalent cross-linked network, then the negative electron group is coordinated with zirconium ions to form an ionic cross-linked network, and the controllable dual-network elastic hydrogel with the mechanical property close to that of soft tissue is constructed. By means of the advantage of constructing a fine structure by means of a photocuring rapid prototyping technology, various personalized tissue and organ models matched with natural soft tissues can be printed and prepared, and the contradiction between the mechanical property and the processability of a soft material is solved. The elastic hydrogel provided by the invention is simple and feasible in preparation method, has adjustable and controllable mechanical properties, can be better matched with soft tissues, can simulate mechanical behaviors of human soft tissues, and is expected to be applied to the medical fields of medical preoperative simulation, organ transplantation and surgical resection.

The invention discloses a macular hole inner limiting membrane transplanting surgical apparatus. The surgical apparatus comprises a handle, an operating rod and a bent sheet. The operating rod is connected with the handle in a head-tail connection mode; the bent sheet is arranged at the end of the operating rod, and an included angle is formed between the bent sheet and the operating rod. When the macular hole inner limiting membrane transplanting surgical apparatus is in use, a doctor can conveniently fill the macular hole with the inner limiting membrane. Even if the inner limiting membrane is larger than the hole, the bent pipe can protrude into the lower portion of macula lutea from the hole, fill the inner limiting membrane with the macula lutea, and level the inner limiting membrane. The handle is provided with a radiating light, thus the doctor is assisted in observation, and surgery is conveniently operated.

This disclosure describes a Descemet's membrane endothelial keratoplasty (DMEK) graft prepared using paired incisions; compositions including the incised DMEK graft; an injector including the incised DMEK graft; a viewing chamber including the incised DMEK graft, methods of preparing the incised DMEK graft; and methods of using the DMEK graft, the compositions, the injectors, and the viewing chambers including to facilitate placement of DMEK grafts during cornea transplant surgery.

The invention provides a transplanted tooth socket hole preparation guide plate which comprises a first base plate and a transplantation guide sleeve arranged on the first base plate, the first base plate is fixedly installed on the periphery of an implanted area, and the movable guide sleeve is used for preparing a tooth root socket of a donor tooth. The transplanted tooth socket hole preparation guide plate is simple in structure and convenient to use, and the difficulty of an autogenous tooth transplantation operation is reduced. The preparation precision of the tooth socket of the implanted area is improved, so that the tooth socket for guiding preparation and the tooth socket for virtual design have a high matching degree, and in addition, the guide plate can also effectively ensure that donor teeth are matched and occluded with the implanted area.

The invention discloses a novel medical hair transplanter, which belongs to the technical field of medical instruments. In order to overcome the defect that only one piece of hair can be planted in one operation action of an existing medical hair transplanting instrument, the medical hair transplanter is provided with a pressing key, multiple sets of hair transplanter assemblies, a chuck, a shelland a protective cap, and the multiple sets of hair transplanter assemblies are controlled by the pressing key in a one-key mode. The transplanter can be used for patients needing hair transplantationoperation treatment clinically. During an operation, a nurse puts hair to be transplanted into each set of hair transplanter assembly for later use, and a doctor presses the pressing key once, so that multiple plants of hair in different operation areas can be implanted at the same time. When the transplanter is used, the operation field of an operation area is clearly distinguished during operation, the defects of uneven stress and mutual extrusion of soft tissues can be avoided, the operation bleeding infection probability can be obviously reduced, tissue trauma is reduced, no trace existsafter healing, the risk of operation complications is obviously reduced, the operation time can be obviously shortened, the hair survival rate is greatly increased, and a large number of manpower andmaterial resources are saved.

The invention provides the use of a calcitonin in the preparation of a medicament for the treatment of an inflammatory disease or condition. The calcitonin may be selected from the group consisting of human, salmon, eel, porcine, bovine, or chicken calcitonin or a derivative, a fragment or a variant thereof. The inflammatory disease or condition may be rheumatoid arthritis (RA), juvenile rheumatoid arthritis (JRA), osteoarthritis, psoriasis, psoriatic arthritis, ankylosing spondylitis (AS), lupus erythamatosis, multiple sclerosis (MS), asthma, or immuno-suppressive therapy (e.g. post transplantation surgery). The treatment may also comprise administration of a glucocorticoid, an anti-rheumatic drug or an antibody.

A surgical instrument and method for implantation of follicular units into the scalp of a patient, including a generally cylindrical handle; a cannula disposed at one end of the cylindrical handle, the cannula having an open port constructed to load and to hold a follicular unit, and the cannula further having a tip end constructed for insertion into an implantation incision at an implantation site; a flap for at least partially closing the open port; a movable lever hinged at one end thereof relative to the cylindrical handle and connected at another end thereof to the flap; and a plunger extending through the cannula and constructed to displace a loaded follicular unit out from the cannula into the implantation incision.

The invention discloses a fixator for a cardiac surgery transplantation operation and a using method thereof, and relates to the technical field of heart transplantation. The fixator comprises a fixator body, side sliding grooves are formed in the two corresponding sides of the fixator body, first sliding blocks are slidably connected into the two side sliding grooves, outer mounting blocks are fixedly mounted on one sides of the two first sliding blocks, first rotating grooves are formed in one sides of the outer mounting blocks, and first rotating connecting columns are rotationally connected into the first rotating grooves. The fixator for the cardiac surgery transplantation operation has the beneficial effects that the two sets of main clamping frames and an auxiliary fixing frame are used, the auxiliary fixing frame can be used for fixing a heart from the lower portion of the heart, the main clamping frames are used for fixing the heart from the two sides of the heart, therefore the heart can be more conveniently fixed, and through a multi-section type rotating mechanism of the auxiliary fixing frame, the fixator can better conform to the surface contour of the heart and is more convenient to use.