98 results about "Pericardium tissue" patented technology

A prosthetic stented heart valve which includes a compressible and expandable stent structure having first and second opposite ends, an expanded outer periphery, and a compressed outer periphery that is at least slightly smaller than the expanded outer periphery when subjected to an external radial force. The valve further includes a valve segment comprising a dual-layer sheet formed into a generally tubular shape having at least one longitudinally extending seam, and a plurality of leaflets formed by attachment of an outer layer of the dual-layer sheet to an inner layer of the dual-layer sheet in a leaflet defining pattern. The valve segment is at least partially positioned within the stent structure. The valve may further include at least one opening in the outer layer of the dual-layer sheet that is spaced from both the first and second ends of the stent structure.

A tubular suction tool for accessing an anatomic surface or anatomic space and particularly the pericardium to access pericardial space and the epicardial surface of the heart to implant cardiac leads in a minimally invasive manner are disclosed. The suction tool incorporates a suction pad concave wall defining a suction cavity, a plurality of suction ports arrayed about the concave wall, and a suction lumen, to form a bleb of tissue into the suction cavity when suction is applied. The suction cavity extends along one side of the suction pad, so that the suction pad and suction cavity can be applied tangentially against a tissue site. The suction tool can incorporate light emission and video imaging of tissue adjacent the suction pad. A working lumen terminating in a working lumen port into the suction cavity enables introduction of tools, cardiac leads, and other instruments, cells, drugs or materials into or through the tissue bleb drawn into the suction cavity.

A transcoronary sinus pacing system comprising a sheath having a lumen, a pacing catheter having a pacing needle, wherein the catheter can be advanced within the lumen and placed in the LV summit, and a right ventricular pacing device. A LV summit pacing device. An early mitral valve closure pacing device configured to operate with a right ventricular apex pacing device. A method for implanting a pacing device at a target coronary sinus tissue location, wherein the target can be the posterior LV summit. A method for achieving early closure of a mitral valve. A method for using visualization devices such as fluoroscopy or ultrasound and/or catheter features such as a radiopaque marker to locate a target location for LV pacing and to avoid piercing an artery or the pericardium when anchoring the LV pacing electrode.

A tubular suction tool for accessing an anatomic surface or anatomic space and particularly the pericardium to access pericardial space and the epicardial surface of the heart to implant cardiac leads in a minimally invasive manner are disclosed. The suction tool incorporates a suction pad concave wall defining a suction cavity, a plurality of suction ports arrayed about the concave wall, and a suction lumen, to form a bleb of tissue into the suction cavity when suction is applied. The suction cavity extends along one side of the suction pad, so that the suction pad and suction cavity can be applied tangentially against a tissue site. The suction tool can incorporate light emission and video imaging of tissue adjacent the suction pad. A working lumen terminating in a working lumen port into the suction cavity enables introduction of tools, cardiac leads, and other instruments, cells, drugs or materials into or through the tissue bleb drawn into the suction cavity.

Apparatus and methods for using the apparatus are disclosed for cardiac restraint. More specifically, the apparatus and methods are directed to accessing the pericardium, accessing the heart within the pericardium, and restraining the heart by at least partially enclosing the heart with the apparatus. An embodiment of a cardiac restraint apparatus according to the present invention comprises a jacket, the jacket having a rim which defines an opening for receiving a heart. The apparatus also comprises a knot pusher that has a hollow elongate body, as well as a strand that extends around the rim of the jacket and is tied into a slipknot. The strand is positioned such that at least one end portion of the strand extends through the knot pusher such that a distal end of the knot pusher can be moved into engagement with the slipknot, whereby pulling the end portion of the strand away from the heart while pushing the knot pusher against the slipknot and reducing the diameter of the opening defined by the rim. In addition, the apparatus comprises one or more guide elements that are attached to the jacket.

Devices, systems and methods are provided which are capable of applying pressure and constraint to the heart and use the pericardium to assist in the application of the pressure and force to the heart.

A recyclable and adjustable interventional stent for intravascular constriction. The stent main body is divided into three parts and shaped like a waist drum with expansion parts (1, 4) being arranged on the upper and lower parts of the stent main body respectively for supporting and positioning. A variable aperture part (2) is arranged in the middle of the stent main body. The upper expansion part (1) is or is not provided with a coating; the middle variable aperture part (2) and the upper half part of the lower expansion part (4) are covered with a pericardium (3) subjected to anti-calcification treatment; and a metal wire ring (5) is passed through the lowermost edge of the stent. A compound conveying guide pipe is composed of an outer sheath (6) and a core (7). The core (7) is a hollow pipe and a wire hanging groove is arranged on the outer side wall of the tip of the pipe to hang the metal wire ring (5) of the lowermost edge of the stent. A fixing bolt (8) on the outer sheath (6) is used for fixing the relative position between the outer sheath (6) and the core (7). The stent is used to replace conventional pulmonary artery banding as, adhesion not being formed around the heart and major vessels and pulmonary stenosis not being formed, difficulties during radical surgery are not increased.

Devices, systems and methods are provided which are capable of applying pressure and constraint to the heart and use the pericardium to assist in the application of the pressure and force to the heart.

Catheters and methods for epicardial ablation are provided. A suitable catheter comprises an elongated catheter body and an ultrasound transducer mounted at or near the distal end of the catheter body. The transducer has a front surface and an opposing back surface, wherein the transducer is positioned to transmit ultrasound energy toward tissue facing the front surface but not toward tissue facing the back surface. A sensor is mounted within the catheter near the ultrasound transducer for sensing a location and an orientation of the ultrasound transducer within a patient. A suitable method involves introducing the distal end of the catheter introducing into the pericardium of a patient. The transducer's front surface is positioned so that it generally faces tissue to be ablated, and the tissue is ablated with ultrasound energy generated by the transducer.

An apparatus for automatically retroperfusing a coronary vein includes an intraluminal cannula having a main body portion extending between a proximal end portion and a distal end portion. The proximal end portion is for connecting to an artery outside of the pericardium to automatically supply oxygenated blood from the artery for retroperfusion. The main body portion and the distal end portion are insertable through a vein that is fluidly connected with the coronary vein and into the coronary vein. An expandable stent is attached to the distal end portion for expanding radially into engagement with the interior wall of the coronary vein to secure the distal end portion at a desired location within the coronary vein. Occluding structure for at least partially occluding the coronary vein is provided at the distal end to decrease the back-flow of blood into the right atrium during retroperfusion. The cannula includes passages that allow a limited amount of blood to bypass the occluding structure.

The present invention is method for permanently compressing tissues in the body. The method employs a compression device made of a spring and a flexible sheet that cooperate to form a compressive envelope around the desired tissue. The spring is preferably Z-shaped or a coil. The sheet is made of a flexible material and the material is preferably elastic. The sheet is preferably a biocompatible elastic material, such as a mesh made of stainless steel or a woven or non-woven elastomer. The method is minimally invasive because it deploys the compression device through the patient's skin directly to the tissue, as opposed to through catheterization or open invasive surgery, such as open-heart surgery. The preferred use is for compressing the left atrial appendage to prevent clots from forming and circulating, thereby preventing strokes. The device is deployed by making an incision in a patient's chest, inserting the compression device through the incision into the pericardium without piercing the heart, and deploying it around the entire appendage. The device remains in place by its own compressive nature: either the spring, the sheet, or both components compress the appendage and cause the device to stay in place due to friction. Preferably the entire compression device is left in place, but the spring or the sheet may be removed, leaving the remaining component to compress the appendage.

The invention provides a preparation method of an ocular surface biofilm, which uses animal pericardium, intestinal membrane and adipose omentum as raw materials through degreasing, decellularization, multi-directional antigen removal, epoxy fixation, curved surface molding, surface Modification, cobalt-60γ-ray irradiation sterilization and other process steps. The ocular surface biofilm obtained by the method of the present invention has a curved surface similar to that of the eyeball, can be close to the eyeball, has no antigenicity, good histocompatibility, can participate in the healing process of ocular surface wounds, and is beneficial to wound healing; Good air permeability and bacterial filtration can play a good role in the protection and treatment of the ocular surface; it has good strength, can be pasted and sewed, and is easy to use. In addition, through the surface modification of drug sustained release, it can also be made into a therapeutic ocular surface biofilm that can release anti-infective drugs slowly.