The invention discloses a bioprosthetic valve and a processing method thereof. The processing method comprises the following steps: flattening a flat pericardial tissue material and fixing the edge; sequentially contacting a pericardial tissue material with the fixed edge with an acellular solution, a cleaning solution, a fixing solution, a capping reagent, a deloading solution and a cleaning solution, forming a pressure difference between the two sides of the pericardial tissue material in the solution contact process, and enabling various solutions to pass through the interior of the pericardial tissue material under the action of the pressure difference so as to finish the treatment of the pericardial tissue material. According to the treatment method disclosed by the invention, phospholipid, cell components, immunogenicity, calcification sites, toxic reagent residues and the like in tissues can be effectively removed, the anti-calcification and anti-coagulation properties of the treated tissue are remarkably enhanced, and the pericardial material can be extruded under the action of pressure, so that the treated pericardial material has excellent mechanical properties.