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31 results about "Octanol water partition" patented technology

Targeted delivery of active/bioactive and perfuming compositions

Described are controlled, time-release microparticulate active and bioactive compositions (including perfuming compositions) for targeted delivery to surfaces such as skin, hair and fabric and the environment proximate thereto, where the active and bioactive materials have a calculated log10P values of between 1 and 8 (P being the n-octanol-water partition coefficient). Such compositions include the active or bioactive material in single phase, solid solution in a wax or polymer matrix also having coated thereon and / or containing a compatible surfactant. Also described are processes and apparatus for preparing such compositions and processes for using same. Furthermore, certain component(s) of the aforementioned compositions in combination with one another are novel, and other components have novel uses in increasing fragrance substantivity, particularly in hair care preparations such as hair gels and shampoos.
Owner:INTERNATIONAL FLAVORS & FRAGRANCES

Apparatus for preparing a solid phase microparticulate composition

Described are controlled, time-release microparticulate active and bioactive compositions (including perfuming compositions) for targeted delivery to services such as skin, hair and fabric and the environment proximate thereto, where the active and bioactive materials have a calculated log10P values of between 1 and 8 (P being the n-octanol-water partition coefficient). Such compositions include the active or bioactive material in single phase, solid solution in a wax or polymer matrix also having coated thereon and / or containing a compatible surfactant. Also described are processes and apparatus for preparing such compositions and processes for using same. Furthermore, certain component(s) of the aforementioned compositions in combination with one another are novel, and other components have novel uses in increasing fragrance substantivity.
Owner:INTERNATIONAL FLAVORS & FRAGRANCES

Reversed liquid crystalline phases with non-paraffin hydrophobes

Compounds which are otherwise difficult to solubilize, such as, for example, pharmaceutical actives difficult for the body to absorb, are solubilized into a composition using a solvent system that is a structured fluid. The structured fluid is a reversed cubic phase or reversed hexagonal phase material, or a combination thereof, which includes a polar solvent, a surfactant and a non-paraffinic liquid with a high octanol-water partition coefficient which does not qualify as a surfactant. The compositions thus formed are able to enhance absorption of drugs by the induction of local, transient nanopores in biomembrane absorption barriers and particularly those in which efflux mechanisms, such as those associated with P-glycoprotein and / or cytochrome 3A4, are active. The compositions and methods that are used for solubilizing pharmaceutical actives in structured fluids can simultaneously accomplish solubilization of difficultly soluble drugs and enhancement of absorption.
Owner:LYOTROPICS THERAPEUTICS INC

Matrix composition comprising surfactant and matrix useful for targeted delivery articles

Described are controlled, time-release microparticulate active and bioactive compositions (including perfuming compositions) for targeted delivery to surfaces such as skin, hair and fabric and the environment proximate thereto, where the active and bioactive materials have a calculated log10P values of between 1 and 8 (P being the n-octanol-water partition coefficient). Such compositions include the active or bioactive material in single phase, solid solution in a wax or polymer matrix also having coated thereon and / or containing a compatible surfactant. Also described are processes and apparatus for preparing such compositions and processes for using same. Furthermore, certain component(s) of the aforementioned compositions in combination with one another are novel, and other components have novel uses in increasing fragrance substantivity, particularly in hair care preparations such as hair gels and shampoos.
Owner:INTERNATIONAL FLAVORS & FRAGRANCES

Molecularly imprinted polymers (MIPS) for the selective removal of inorganic contaminants from liquids

InactiveUS20070090058A1Effective and efficient extractionEffective and efficient and removalSedimentation separationEvaporationIndustrial effluentMolecularly imprinted polymer
A method of creating a cationic molecularly imprinted polymer bead that can bind inorganic target compounds is disclosed and described. The cationic molecularly imprinted polymer bead can be formed by complexing a target compound with a cationic ligand, polymerizing the cationic ligands to form the bead, and then extracting the target compound from the bead. The cationic ligand complex can have an octanol water partition coefficient of about 1 to about 10. The cationic molecularly imprinted polymer bead can have a porous structure containing a plurality of complexing cavities for selectively bind specific target compounds for removal from potable water, mine effluent, industrial effluent, or other fluids.
Owner:MIP SOLUTIONS

Perfume compositions

This invention is concerned with perfume compositions comprising: a) nitrile perfumery material of general formula RCN where R is a hydrocarbyl radical of formula CxHy, x is an integer in the range 9 to 12, and y is an integer in the range 15 to 25; and b) hydrocarbon perfumery material having a boiling point of less than about 185° C. and an octanol-water partition coefficient of at least 4.0 (in logarithmic form), wherein a) and b) together comprise at least 20% by weight of the total weight of the composition. Perfume compositions in accordance with the present invention provide a good deodorant effect several hours after application to a surface such as fabric or skin.
Owner:QUEST INTERNATIONAL

Liquid cleaning compositions

Liquid cleaning compositions are described herein that include a metal bleach catalyst which is a complex of a transition-metal and a macrocyclic ligand, the ligand having a calculated Octanol / Water Partition Coefficient value of from about −1.50 to about −0.10, a formulation enabling fraction comprising at least one formulation enabling ingredient, the formulation enabling fraction having a Hydrophilic Index of from about 4.0 to about 10.0, and a formulation deactivating fraction comprising at least one formulation deactivating ingredient that has a calculated Octanol / Water Partition Coefficient value of from about −3.5 to about −0.10.
Owner:THE PROCTER & GAMBLE COMPANY

Water base pigment ink for ink-jet recording, ink cartridge accommodating the same, and ink-jet recording method

A water base pigment ink for ink-jet recording contains a pigment, a propylene glycol derivative which has a saturation vapor pressure of 2 to 10 hPa and an octanol-water distribution coefficient log P of 0 to 1.35, and dipropylene glycol-n-propyl ether. The propylene glycol derivative is contained in the ink by 0.25 to 1.5% by weight, and the dipropylene glycol-n-propyl ether is contained in the ink by 0.5 to 1% by weight. The ink is excellent in the paper surface drying performance. Further, it is possible to avoid the occurrence of the feathering and the blank stripes in letters.
Owner:BROTHER KOGYO KK

Cleaning composition, cleaning agent as well as preparation methods and applications thereof

The invention discloses microcapsules, a preparation method thereof, cleaning composition containing the microcapsules and a cleaning agent. The cleaning composition is prepared from the following components by mass: 5wt%-90wt% of a surfactant and 0.01wt%-10wt% of the microcapsules wherein the microcapsules contain hollow polymer microspheres with microporous channels in the surface and substanceswith fragrance and / or special smell and / or special functions; the substances with fragrance and / or special smell and / or special functions are not limited by functional groups, ClogP (partition coefficient octanol / water) and water solubility; the surfactant in the cleaning composition is preferably a novel green and environment-friendly nonionic surfactant (alkyl ethoxy polyglycosides), and the cleaning composition and the cleaning agent with excellent performance and environmental friendliness are obtained from the surfactant and the microcapsules through compounding and widely used in the fields of fabric cleaning agents, tableware cleaning agents, floor cleaning agents, carpet cleaning agents, skin cleaning agents, hair cleaning agents, deodorant and the like.
Owner:GUANGZHOU BLUE MOON IND

Weakly basic 2-nitroimidazoles for the non-invasive detection of tissue hypoxia

The present invention incorporates weakly basic substituents (pKa about 8 or greater) such as pyrrolidine, piperidine, piperazine and azapane moieties in halogenated 2-nitromidazoles as a major improvement over prior art for the non-invasive detection of cellular hypoxia in normal and malignant tissues. The invention features the use of [18F] positron emission tomography, [19F] magnetic resonance spectroscopy, and [19F] magnetic resonance imaging. Improvements over prior art compounds are six-fold. 1) Salts of weakly basic reagents are highly water-soluble which facilitates administration. 2) Unreacted reagents are rapidly cleared from systemic circulation thereby decreasing background noise. 3) Reagents with weakly basic substituents are concentrated in tissue ˜3 fold above plasma levels thereby increasing binding intensity and enhancing signal detection. 4) Conjugate bases of weakly basic reagents have intermediate octanol-water partition coefficients that facilitate their penetration into all tissues including brain. 5) Cellular adducts of reagents containing weakly basic substituents are more stable than reagents of prior art. 6) Reagents with weakly basic substituents are effective for the detection of transient hypoxia in solid tissue.
Owner:NATURAL PHARMACIA INT

Chloroprene graft copolymer latex, method for producing same, bonding agent and adhesive

Provided is a method for producing a chloroprene graft copolymer latex containing no organic solvent and exhibiting high adhesive strength even for soft polyvinyl chloride. A method for producing a chloroprene graft copolymer latex includes a chloroprene polymerization step of giving a chloroprene polymer latex and a graft copolymerization step of giving a chloroprene graft copolymer latex. The chloroprene polymerization step is a step of subjecting at least chloroprene (A-1) of chloroprene (A-1) and a monomer (A-2) copolymerizable with chloroprene (A-1) to emulsion radical polymerization. The graft copolymerization step is a step of adding, to the chloroprene polymer latex, a (meth)acrylate (B) and an organic peroxide (C) having an octanol / water partition coefficient of −2.0 or more and 3.0 or less to subject the chloroprene polymer to graft copolymerization with the (meth)acrylate (B) at a temperature of 10° C. or more and 40° C. or less.
Owner:RESONAC CORP

Method for measuring octanol-water distribution coefficients of surfactants

The present invention provides a procedure for determining the octanol-water distribution coefficient P of a surface-active substance by means of the following steps:1. equilibrating a dilute aqueous solution or dispersion of the substance with octanol2. evaporating an aliquot of the aqueous phase and re-dissolving the residue in water or electrolyte solution3. measuring of the surface tension of the re-dissolved residue solution4. determining the concentration of the surface-active substance in the re-dissolved residue solution by means of a surface tension vs. concentration calibration curve5. using the concentration of the surface-active substance in the re-dissolved residue solution to calculate the equilibrium concentration in the aqueous phase and, from the mass balance, the equilibrium concentration in the octanol phase6. calculating the octanol-water distribution coefficient from the ratio of concentrations in octanol and water phases.
Owner:CLARIANT FIANCE (BVI) LTD

Blocked aliphatic thiol stabilizers for photothermographic materials

InactiveUS20060141403A1Improving Desktop Print StabilityWithout significant loss in desired sensitometric propertyX-ray/infra-red processesRadiation applicationsThiolStabilizing Agents
Photothermographic materials contain one or more blocked aliphatic thiol compounds in an amount of at least 1 mg / m2 as stabilizers. These compounds have a calculated octanol-water partition coefficient (c log P value) of 2.0 or greater, and an N value equal to or greater than 6.5.
Owner:CARESTREAM HEALTH INC

Stable oil-soluble polypeptide composition and preparation method and application thereof

ActiveCN110339081AEasy to storeAvoid dissolved oxygen oxidationCosmetic preparationsMake-upGlycerolSolvent
The invention belongs to the field of cosmetics, and discloses a stable oil-soluble polypeptide composition, which comprises the following components: polypeptide, a solubilizing agent, and an oily solvent; the solubilizing agent has an octanol water partition coefficient of 1.70 to 1.90 or an HLB value of 8.0 to 10.0; the polypeptide is selected from at least one of palmitoyl tripeptide-7, palmitoyl tripeptide-1, palmitoyl tripeptide-5, palmitoyl tripeptide-8, palmitoyl tetrapeptide-5, palmitoyl tetrapeptide-7, palmitoyl tetrapeptide-10, and palmitoyl pentapeptide-4; and the solubilizing agent is at least one selected from the group consisting of ethylhexylglycerin, glycerol caprylate, polyoxyethylene fatty acid, sorbitan laurate, and polyoxyethylene oxypropylene oleate. The oil-soluble polypeptide composition of the present invention is easy to be added to a cosmetic of a full oil formula, and has good compatibility, the stability of the oil-soluble polypeptide composition is good, the product is not easy to grow bacteria, compared with traditional water-soluble peptide products, the product does not need to add preservatives, and the formula is safer.
Owner:ZHUHAI JINBAIKANG BIOLOGICAL TECH CO LTD

Papermaking additive, paper, and paper manufacturing method

ActiveCN112601860AExcellent paper strengthReinforcing agents additionPaper/cardboardPolymer scienceMeth-
The present invention addresses the problem of providing: a polyacrylamide-based papermaking additive having an excellent paper strength-enhancing effect; paper in which the papermaking additive is used; and a paper manufacturing method in which the papermaking additive is used. A papermaking additive containing an amphoteric polyacrylamide containing, as copolymerization components, (A) (meth)acrylamide, (B) a (meth)allyl sulfonic acid, (C) an anionic vinyl monomer having a carboxyl group, and (D) a cationic vinyl monomer having a quaternary ammonium, wherein the papermaking additive is characterized in that the ratio of the anion equivalent and cation equivalent of the amphoteric polyacrylamide is 0.05 to 1.7, the octanol / water partition coefficient of the amphoteric polyacrylamide is -1.44 to -0.60, and the surface tension of the amphoteric polyacrylamide is 66 mN / m to less than 74 mN / m.
Owner:SEIKO PMC CORP

Care composition, care agent as well as preparation methods and applications thereof

The invention discloses care composition, a care agent as well as preparation methods and applications thereof. The care composition is prepared from components in percentage by mass as follows: 1wt%-50wt% of a surfactant and 0.01wt%-10wt% of microcapsules. The microcapsules for the preparation method of the care composition are added to a care agent system and can be deposited on the surfaces ofto-be-cared substances such as fabric, skin and hair or reserved in the to-be-cared substances such as gaps of fabric fibers in a physical absorption or chemical absorption manner. A selected core substance is not limited by functional groups, octanol-water distribution coefficient, polarity and water solubility; preferably, the surfactant is selected from biodegradable alkyl ester based quaternary ammonium salt and a novel green and environment-friendly nonionic surfactant (alkylethoxyglucoside), and the care composition prepared from the surfactant and the microcapsules through compounding is better in stability, can keep aroma for a long time and is greener and more environmentally friendly.
Owner:GUANGZHOU BLUE MOON IND

Polymer adsorbent / cellulose acetate composite membrane material and preparation method and application thereof

The invention discloses a polymer adsorbent / cellulose acetate composite membrane material and a preparation method and application thereof. The preparation method of the composite membrane material comprises the following steps: dissolving a polymer adsorbent and a cellulose acetate polymer into a solvent to obtain a film casting solution; and forming a film from the film casting solution to obtain the composite membrane material. The composite membrane material can be used for enrichment and passive collection of hydrophobic organic pollutants and hydrophilic organic pollutants from water bodies; the logKow of the hydrophobic organic pollutants or the hydrophilic organic pollutants is 1.49-9.47, Kow is octanol-water partition coefficient, and the organic pollutants comprises organic phosphate flame retardants, phenols, estrogen, organophosphorus pesticides and triazine pesticides and other organic compounds. The polymer adsorbent in the composite membrane material is particularly important for the passive collection of trace pollutants (usually nanogram per liter level) in the water environment, can be used for enrichment of pollution with the concentration time reaching 10<3>-10<6>, and greatly reduces the detection limit of the pollutants.
Owner:RES CENT FOR ECO ENVIRONMENTAL SCI THE CHINESE ACAD OF SCI

A kind of polymer adsorbent/cellulose acetate composite membrane material and its preparation method and application

The invention discloses a polymer adsorbent / cellulose acetate composite membrane material and a preparation method and application thereof. The preparation method of the composite membrane material comprises the following steps: dissolving a polymer adsorbent and a cellulose acetate polymer into a solvent to obtain a film casting solution; and forming a film from the film casting solution to obtain the composite membrane material. The composite membrane material can be used for enrichment and passive collection of hydrophobic organic pollutants and hydrophilic organic pollutants from water bodies; the logKow of the hydrophobic organic pollutants or the hydrophilic organic pollutants is 1.49-9.47, Kow is octanol-water partition coefficient, and the organic pollutants comprises organic phosphate flame retardants, phenols, estrogen, organophosphorus pesticides and triazine pesticides and other organic compounds. The polymer adsorbent in the composite membrane material is particularly important for the passive collection of trace pollutants (usually nanogram per liter level) in the water environment, can be used for enrichment of pollution with the concentration time reaching 10<3>-10<6>, and greatly reduces the detection limit of the pollutants.
Owner:RES CENT FOR ECO ENVIRONMENTAL SCI THE CHINESE ACAD OF SCI
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