82 results about "Nail tinea" patented technology

Since treatment effects of conventional external preparations were not satisfactory, it is aimed to provide a novel external preparation that is excellent in drug permeability to nail, capable of fully exhibiting effects of an antifungal drug, and effective for treatments of diseases such as nail mycosis and nail candidiasis, particularly, treatments for nail tinea. The external preparation of this invention is a pharmaceutical composition for nail characterized by containing an antifungal drug, alkylpyrrolidone or a derivative thereof, and a crosslinking hydrogel.

The invention discloses a drug used for curing tinea of feet and hands and tinea unguium, and the drug is prepared by fructus bruceae, cortex pseudolaricis, radix stemonae,cortex dictamni and radices sophorae flavescentis which are ground to powder and are put in a gauze bag which is then soaked in glacial acetic acid with the concentration of 30 percent or 30-degree vinegar essence for one week; and then the obtained mixture is filtered, sterilized and bottled so as to obtain the drug. By virtue of the compatibility of the raw materials, the drug used for curing the tinea of feet and hands and the tinea unguium of the invention has the functions of clearing away heat and toxic materials, drying and eliminating dampness, killing parasites to relieve itching, diminishing inflammation, resisting and killing eumycetes and softening and moistening and has obvious effect on killing the eumycetes caused by the tinea of feet and hands and onychomycosis. The drug of the invention utilizes pure natural Chinese medical herbs to treat the tinea of feet and hands and the tinea unguium, thus avoiding damage caused by taking orally to liver and kidney, and having convenient use, instant effect and short course of treatment and no recrudescence after the treatment. The drug of the invention also has good effect on curing scald head and psoriasis.

The present invention provides a Chinese medicine and Western medicine combined liniment for external application for curing the diseases of chronic intractable dermatitis, dermophytosis, tinea cruris, tinea manuum, tinea pedis, psoriasis, ulcer of skin, infection of skin, scabies, pruritus cutanea, tinea unguium and leuconychia, etc. with obvious therapeutic effect. Said medicine preparation is made up by using the Chinese medicinal materials of cnidium seed, stemona root, sulfur, shrubalthea bark, mylabris, camphor and salicylic acid. Besides, said invention also provides the concrete steps of its preparation process.

The present invention relates to the externally applied Chinese medicine composition for treating tinea unguium and its preparation process. The medicine is ointment prepared with sessile stemona root, broom cypress fruit, shrubalthea bark, flavescent sophora root, cnidium fruit and other Chinese medicinal materials. The present invention features being waterproof, unique preparation process and obvious curative effect.

The invention is concerned with a kind of traditional Chinese and western medicine and ite preparation method and quality control method to cure athlete's foot, ringworm of the hand and tinea unguium. It relates to 10 to 500 mL compound coral ginger tincture, 1 to 50 g oxybenzoic acid, 1 to 50 g glycerin and 1 to 50 g acetic acid, and with some assistant materials. The preparation of this invention uses traditional Chinese and western medicine to adjust the balance of qi and blood of crus cerebri and kill fungus. The tincture has strong osmosis to solve horn of skin with better cure effect. The nebula added with film forming agent can reduce the volatilization of madicine and keep work for long time. The prepared liniment is easy for use and has perfect effect. This quality control method cotrols the quality of medicine and keeps the cure effect and safety.

The invention provides an antifungal drug composition for external use, and a preparation method of an external preparation, and application of the composition in treating superficial fungal infections, such as tinea manus and pedis, tinea corporis, tinea cruris, tinea unguium, tinea versicolor and oidiomycosis cutis. The drug composition contains terbinafine or pharmaceutical salt thereof, sertaconazole or pharmaceutical salt thereof, and any one or multiple pharmaceutically acceptable excipient. An experimental study shows that the terbinafine or pharmaceutical salt thereof and the sertaconazole or pharmaceutical salt thereof have obvious synergistic effect when the proportion thereof in the drug composition for treating the superficial fungal infections is (1: 10) to (5: 1)(w / w). The antifungal drug composition for treating the superficial fungal infections has the advantages of being good in security, excellent in curative effect, short in treatment course, high in curing rate, low in relapse rate and the like.

It is an object of the invention to provide a kit and method for identification of causative fungi of tinea unguium, which allows rapid and accurate identification of causative fungi by real-time PCR using primer sets and probes specific for fungal species. An identification kit for identification of causative fungi of tinea unguium using real-time PCR, which comprises a primer set and a probe, wherein the primer set is at least one selected from the group consisting of a primer set consisting of a primer comprising the nucleotide sequence as set forth in SEQ ID NO: 1 and a primer comprising the nucleotide sequence as set forth in SEQ ID NO: 2, and a primer set consisting of a primer comprising the nucleotide sequence as set forth in SEQ ID NO: 3 and a primer comprising the nucleotide sequence as set forth in SEQ ID NO: 4, and wherein the probe is at least one selected from the group consisting of a probe comprising the nucleotide sequence as set forth in SEQ ID NO: 5 and a probe comprising the nucleotide sequence as set forth in SEQ ID NO: 6.

The present invention is directed to a nail lacquer consisting essentially of terbinafine as an antimycotic agent, hydroxypropyl chitosan as film forming agent, water and a lower alkanol as solvents. The invention is also directed to a method for treating onychomycosis by topically administering such a nail lacquer to a patient in need of such a treatment.

The antiseptic for preventing and treating tinea unguium, tinea manus and tinea pedes as one kind of Chinese medicine preparation is prepared with malaytea scurfpea fruit, clove, dried old orange, pseudolarix, flavescent sophora root, garlicin, glacial acetic acid and deionized water in certain weight proportion. The antiseptic of the present invention has simple recipe, convenient use, less irritation and no toxic side effect.

The invention relates to sterilizing liquid for treating various skin diseases such as psoriasis. In the sterilizing liquid, the biological raw materials of plum-leaf crab, conch, oyster, clam shell, willow mushroom and centipede are adopted. The preparation can be used for killing various skin germs, particularly has a good treatment effect on intractable psoriasis, eczema, bromhidrosis, tinea unguium, scabies, pruritus and vegetative allergy, is free from toxic and side effects. The sterilizing liquid has the characteristics of high efficiency, rapidness and low relapse rate. A therapy method of cleaning an affected part by using a low-concentration liquid medicament and dressing by using a high-concentration liquid medicament is adopted. The sterilizing liquid is lower in cost, quick in response, and very easy and convenient for treating. The sterilizing liquid is an environment-friendly medicament since only water is taken as a leaching agent without any inorganic chemical additive.

The invention relates to an ointment and medicine composite formula for removing tinea unguium and a preparation method thereof. The ointment comprises 3-5% of lithargyrum, 1-2% of calomel, 8-12% of potassium iodide, 3-6% of amorolfine, 25-35% of vaseline, 8-12% of lanolin, 25-35% of allantoin, and the balance of zinc oxide and white wax which account for 50% respectively. The medicine comprises 15-25% of radix stemonae, 15-25% of radix sophorae flavescentis, 15-25% of pseudolarix, 15-25% of balsam, 5-10% of borneol and the balance of vinegar. The preparation method comprises the following steps of: (1) mixing and stirring the accessories of the ointment, and heating to obtain ointment; and (2) grinding the accessories of the medicine into powder, and mixing the powder with the vinegar to obtain the medicine. The ointment is smeared to soften the nails with tinea unguium, and the medicine is applied to kill fungi and promote the growth of new nails. Through the invention, the cure rate is high, and the reoccurrence of tinea unguium can be effectively suppressed; and the ointment and medicine provided by the invention are safe without side effect and have an obvious curative effect and a short treatment period.

The invention discloses an externally applied traditional Chinese medicine powder for diminishing inflammation and swelling, which is prepared from the following raw material medicines by weight percentage: 20-30% of realgar, 25-35% of rhubarb, 10-20% of turmeric, 10-20% of cortex phellodendri, and 10-20% of bulbus fritillariae thunbergii. The externally applied powder for diminishing swelling isprepared by the compatibility of only five raw material medicines, has the efficacies of promoting blood circulation and removing blood stasis, diminishing swelling and relieving pain, expelling stasis and stagnation, and promoting pus discharge and tissue regeneration. The externally applied traditional Chinese medicine powder is simple in compatibility, distinct in treatment effect, and short in course of treatment, and does not have toxic or side effect. The externally applied powder for diminishing swelling can treat acute and chronic lobular hyperplasia of mammary glands, lymphnoditis, mumps, traumatic injuries, lipoma, furuncle, pustule of finger tip, paronychia, tinea unguium, external piles, anus abscess and hemangioma, with wide treatment range and low cost, and also can be used for treating mammary gland disease and foot-and-mouth disease of cows, with very good treatment effect.

The invention belongs to the field of natural medicine and cosmetics, and provides application of Chinese torreya essential oil to preparation of anti-dermatophytes medicine, or application of Chinese torreya essential oil as efficiency ingredients in cosmetics for inhibiting the dermatophytes. In-vitro antibacterial activity study on the Chinese torreya essential oil shows that the Chinese torreya essential oil has better antibacterial activity on common pathogenic dermatophytes capable of causing tinea capitis, tinea corporis and little onychomycosis. The Chinese torreya essential oil is essential oil prepared from Chinese torreya aril by a distillation method, a cold squeezing method, a solvent extracting method or a carbon dioxide supercritical extraction method and the like. The Chinese torreya essential oil has the quality requirements that the Chinese torreya essential oil is colourless to yellowish Green liquid, and has the characteristic flavor of Chinese torreya fruit; the relative density (20 DEG C / 20 DEG C) is 0.850 to 0.860; the content sum of characteristic components of Alpha-pinene and limonene is greater than or equal to 30 percent. The invention discloses a new purpose of the Chinese torreya essential oil to prepare anti-dermatophytes medicine or cosmetics. In addition, an optimized preparation method of the Chinese torreya essential oil is provided by comparing the advantages and disadvantages of different extraction methods of the Chinese torreya essential oil.

To provide a solution applicator with which irritation on an affected part of a patient may be reduced even when a solution is used.According to the present invention, an applicator comprises a solution container which comprises an opening, and a columnar brush member formed by bundling synthetic fibers in a columnar shape. The columnar brush member is disposed at the opening of the solution container, a tip portion of the columnar brush member at an outside of the solution container has a fan shape expanding in a perpendicular lateral direction against a pillar axial lengthwise direction, and a thickness of the fan-shaped tip portion of the columnar brush member decreases in a perpendicular lengthwise direction against the pillar axial lengthwise direction toward the tip portion of the columnar brush member. The solution applicator of the present invention has the fan-shaped tip portion so that irritation on an affected part may be decreased and a liquid tinea unguium medicine may be applied to the affected part.

The invention relates to the technical field of ultraviolet therapy, in particular to an ultraviolet therapeutic instrument used for treating tinea unguium. The ultraviolet therapeutic instrument used for treating tinea unguium is provided with a treating glove. The treating glove comprises a glove body and a cavity body which is located inside the glove body and is capable of containing the palm, wherein an ultraviolet electric heating pipe layer is arranged at the top of the cavity body, and a heat preservation layer is arranged under the ultraviolet electric heating pipe layer. The ultraviolet therapeutic instrument used for treating tinea unguium is simple in treating method and obvious in treating effect.

The present invention discloses medicinal liquor for treating a plurality of skin diseases. The medicinal liquor is prepared through the following steps: carrying out treatments of mixing, immersing, filtering and residue removing for raw medicine and wine having a alcohol degree of 50-60 DEG, wherein the raw medicine comprises honeysuckle, hawthorn, red bean, rhubarb, cape jasmine, indian pokwees root, Chinese wolfberry root-bark, panax notoginseng, licorice root, amur corktree bark, garden radish seed, scutellaria lateriflora, Chinese starasmine stem, chrysanthemum, blackberry lily, sessile stemona root tuber and figwort. The medicinal liquor can be provided for treating eczematous dermatitis, mosquito biting, beriberi, miliaria, psoriasis vulgaris, skin itching, early skin cancerous swellings, burns and scalds, acne, exanthema, skin allergy, hand tinea unguium and foot tinea unguium, unrecognized skin affections, sores due to toxic heat and biting, herpes zoster, genital ulcer, syphilis and other skin diseases. According to the present invention, the medicinal liquor provided by the present invention is prepared from the pure traditional Chinese drugs; the medicinal liquor has effects of heat clearing and detoxication, swelling subsiding and pain relieving, wind-evil dispelling and collateral dredging, and the like; the medicinal liquor is mainly provided for treating a plurality of skin viruses; the medicinal liquor can be orally taken, or be adopted for external application so as to provide a effect of combined internal-external therapy; the medicinal liquor has characteristics of safety, no side effects, good therapeutic effect and rapid effectiveness.

The invention discloses an external traditional Chinese medicine preparation for treating tinea unguium and a preparation method thereof. The external traditional Chinese medicine comprises the following raw material medicines: 20-30 parts of golden cypress, 25-35 parts of radix sophorae flavescentis, 20-30 parts of rhizoma smilacis glabrae, 25-35 parts of Radix Stephaniae Tetrandrae, 5-10 parts of Chinese gall and 5-10 parts of realgar. The method comprises the following steps: (1) crushing the raw material medicines, mixing, adding 7-9 weight times of water, heating and performing reflux extraction for 1.5-2.5 hours, filtering to obtain liquid medicines and decoction dregs respectively; (2) adding 5-7 weight times of water into the decoction dregs, heating and performing reflux extraction for 1.5-2.5 hours, merging the filtered liquid medicine and the liquid medicine in the step (1), concentrating to the density of 1.05-1.1g / cm<3>; and (3) adding ethanol into the concentrated solution, standing for over 24 hours, separating and recovering the ethanol in the supernatant, thus obtaining the external traditional Chinese medicine preparation. The external traditional Chinese medicine preparation is simple and effective to use, economic, convenient, easy to operate and contributes to popularization and application, and a patient is not needed to be in hospital.

The invention relates to a traditional Chinese medicine preparation for treating tinea of feet and hands and tinea unguium. According to the technical scheme adopted by the invention, the traditional Chinese medicine preparation is prepared from zanthoxylum schinifollum, radix sophorae flavescentis, radix angelicae, golden larch bark, salicylic acid, cortex phellodendri, scutellaria root, catnip, flos magnolia, cortex moutan radicis, benzoic acid and glacial acetic acid. The traditional Chinese medicine preparation has the functions of softening hard mass and killing insects, killing and inhibiting bacteria, and accelerating and improving repair of cell tissue; the traditional Chinese medicine preparation can be directly applied to the focuses of patients with tinea of feet and hands, tinea unguium, yellowed nails, melanonychia, split tinea unguium, keratinized and thickened nails, defective tinea unguium and stripped tinea unguium; the traditional Chinese medicine preparation is excellent in permeability, obvious in curative effect, short in treatment course, free of pain and free of recurrence after healing; through years of clinical application, the traditional Chinese medicine preparation is obvious in effect and high in curative rate; the total effective rate can reach over 97%.

The invention discloses an anti-inflammation detoxification sterilization medicine composition which is prepared by processing the following seven plants: Houttuynia cordata Thunb, sedum sarmentosum Bunge, stem leaves of dendranthema indicum (L) Des Moul, stem leaves of luffa cylindrica, opuntia stricta, aloe baradersis and mentha haplocalyx. The medicine composition disclosed by the invention has the advantages that by virtue of the rational refining of the seven plants with effects of sterilization, disinfection, detoxification and itching relief, the medicine composition combines the advantages of each component, can quickly and effectively treat diseases such as anal eczema, urticaria, blood-heat erythema, athlete foot, tinea unguium, prickly heat and insect bite, has good safety performance and can be applied to old people, children and people with allergic constitution.

Pharmaceutical compositions and methods for treating skin or mucus fungal infections of feet, nails, groin, hands, tongue and other locations are disclosed herein. The pharmaceutical composition disclosed herein comprises at least one triazole agent. Methods of treating tinea pedis, tinea manuum, tinea unguium, tinea cruris, tinea corpora, tinea versicolor, candidiasis, aspergillosis, onychomycosis, coccidiodomycosis, cryptococcal meningitis, histoplasmosis, hoof thrush, hoof rot, tongue and mouth lesions, seborrheic dermatitis, and combinations thereof, are also presently disclosed.

The invention discloses a tinea unguium grease which is prepared from the following medicinal herbs (by weight ratio): chaulmoogra seed 100g, licorice root 60g, roor of sessile stemona 30g, flavescent sophora root 30g, cnidium fruit 30g, apricot kernel 40g, pricklyash peel 15g, ledebouriella root 15g, safflower 15g, sulfur flour 20g and dahurian angelica root 20g.

The invention discloses a moistening and nursing type Chinese medicine foot mask. The foot mask is mainly made from, by weight, 5-10 parts of angelica sinensis, 10-20 parts of radix angelicae, 2-4 parts of ligusticum wallichii, 3-5 parts of apricot kernels, 5-10 parts of rhizoma typhonii, 10-15 parts of Chinese honeylocust fruits, 6-10 parts of hyaluronan acid, 0.2-0.4 part of vitamin E, 0.3-0.5 part of wool grease, 10-20 parts of pearl powder, 3-5 parts of glycerium, 5-15 parts of yoghourt, 2-4 parts of cetostearyl alcohol and 10-20 parts of purified water. The moistening and nursing type Chinese medicine foot mask can rapidly improve the water-retaining property, tightness and elasticity of foot skin, has a good auxiliary treatment effect on beriberi and tinea unguium, can make foot skin smooth and healthy if used frequently, and is comfortable and convenient to use. All the raw materials are pure natural Chinese herbs, and the foot mask is free of any toxic and side effects, easy to make, good in effect and convenient to use for ordinary people.

The invention relates to a novel ointment for treating a microorganism infection skin disease and a preparation process thereof. The novel ointment for treating the microorganism infection skin disease consists of the following materials in part by mass: 0.1 to 0.3 part of trivalent silver ion compound, 0.2 to 0.4 part of keratinase, 0.5 to 5 parts of water-soluble keratin, 2 to 3 parts of composite vitamin and 94.3 to 98.7 parts of white petroleum jelly. The preparation process particularly comprises the following steps of: grinding 0.1 to 0.3 part of trivalent silver ion compound, 0.2 to 0.4 part of keratinase, 0.5 to 5 parts of water-soluble keratin and 2 to 3 parts of composite vitamin into powder; and adding 94.3 to 98.7 parts of white petroleum jelly into the powder and uniformly mixing the mixture. The ointment has the effects of rapidly sterilizing and relieving itching, expelling toxin and removing rot, and repairing skin. The ointment is suitable for treating and protecting a local skin disease caused by microorganism infection, such as fugal infection of hand and foot, tinea corporis, tinea cruris and onychomycosis (ringworm of the nails) caused by fungi, erysipelas and leprosy caused by bacteria, chicken pox, flat wart and herpes caused by virus and the like.

The present invention discloses medicinal liquor for treating a plurality of skin diseases. The medicinal liquor is prepared through the following steps: carrying out treatments of mixing, immersing, filtering and residue removing for raw medicine and wine having a alcohol degree of 50-60 DEG, wherein the raw medicine comprises honeysuckle, hawthorn, red bean, rhubarb, cape jasmine, indian pokwees root, Chinese wolfberry root-bark, panax notoginseng, licorice root, amur corktree bark, garden radish seed, scutellaria lateriflora, Chinese starasmine stem, chrysanthemum, blackberry lily, sessilestemona root tuber and figwort. The medicinal liquor can be provided for treating eczematous dermatitis, mosquito biting, beriberi, miliaria, psoriasis vulgaris, skin itching, early skin cancerous swellings, burns and scalds, acne, exanthema, skin allergy, hand tinea unguium and foot tinea unguium, unrecognized skin affections, sores due to toxic heat and biting, herpes zoster, genital ulcer, syphilis and other skin diseases. According to the present invention, the medicinal liquor provided by the present invention is prepared from the pure traditional Chinese drugs; the medicinal liquor has effects of heat clearing and detoxication, swelling subsiding and pain relieving, wind-evil dispelling and collateral dredging, and the like; the medicinal liquor is mainly provided for treating a plurality of skin viruses; the medicinal liquor can be orally taken, or be adopted for external application so as to provide a effect of combined internal-external therapy; the medicinal liquor has characteristics of safety, no side effects, good therapeutic effect and rapid effectiveness.

The invention discloses a traditional Chinese medicine preparation for treating tinea unguium and a preparation method of the traditional Chinese medicine preparation. The traditional Chinese medicine preparation is prepared from the traditional Chinese medicine main materials used raw materials through fermentation. A fermentation agent comprises biological enzymes and beneficial bacteria of the traditional Chinese medicine main materials; the traditional Chinese medicine main materials comprise the following components: cortex pseudolaricis, gynura bicolor, pine needles, hedyotis diffusa willd, dandelion, wild chrysanthemum, plantain herb and folium mori. According to the invention, fresh Chinese herbal medicines are used as raw materials, heating is not required in the whole production process, no chemical component is added, biological enzymes and beneficial bacteria of the fresh traditional Chinese medicines are fully used to be prepared into a microbial bacterium preparation through natural fermentation, and effective constituents in the medical materials are released fully, so that the contents of effective constituents, vitamins and trace elements in the product traditional Chinese medicine are increased greatly, the treatment effect is excellent, a preparation process is simple, industrialization is facilitated, and the effective rate reaches 90% or above after the traditional Chinese medicine preparation is used by 86 patients with tinea unguium.

The invention relates to a pair of health cloth shoes with the function of treating tinea unguium and a manufacturing method of the pair of health cloth shoes. According to the pair of health cloth shoes, cloth pads are embedded into the shoe soles and the shoe uppers of the health cloth shoes, and contain anti-microbial Chinese herbal medicinal ingredients. Specifically, the cloth pads comprise the following Chinese herbal medicinal ingredients in parts by weight: 20-40 parts of divaricate saposhnikovia root, 10-15 parts of flos magnoliae, 2-4 parts of myrrh, 5-10 parts of fructus corni, 14-25 parts of tuberculate speranskia herb, 3-9 parts of fructus gardeniae, 6-15 parts of radix scutellariae, 1-4 parts of rhizoma coptidis, 8-25 parts of cortex phellodendri, 2-5 parts of honeysuckle flowers, 10-25 parts of cortex magnoliae officinalis, 12-25 parts of radices paeoniae alba, 25-30 parts of flos caryophylli, 12-18 parts of lignum sappan, 15-20 parts of cassia seeds, 20-30 parts of rhizoma alpiniae officinarum, 15-40 parts of Chinese prickly ash, 25-50 parts of herba cirsii japonici, 5-10 parts of radix astragali, 5-8 parts of rhizoma curcumae, 1-2 parts of herba asari, 4-12 parts of scallion stalk, 20-50 parts of mint, and 18-30 parts of alum.

Provided is a device for treating tinea unguium which allows unrestricted treatment even for patients with basic diseases such as liver diseases, pregnant women and lactating patients and by which interindividual difference in the treatment can be avoided and antifungal agent for external use can be transdermally absorbed from the nail surface to the deep part of the nail economically, safely and efficiently within a short period of time without any side effects. A dome-shaped applicator, which is formed of a flexible material, which has an open part provided with a flange for adhesion and which is formed to have a larger film thickness in the periphery adjacent to the open part than the film thickness in other parts, is hermetically bonded to a surface of a nail. Then, the liquid antifungal agent for external use is fed into the dome-shaped applicator under pressure using an injector and is allowed to be efficiently penetrated into the deep part of the nail using positive pressure.

The present invention relates to externally applied compound gel, and especially a kind of externally applied compound gel with Terbinafine Hydrochloride (TER-HCL) and Clobetasol Propionate (CBT) as main components and its preparation process. The externally applied compound gel is used in treating tinea, candida caused skin infection, mould caused tinea unguium, etc. The present invention has convenient use and high healing rate.