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74 results about "Genital warts" patented technology

A sexually transmitted disease resulting in a small lump or swelling on the genitals.

Pharmacological agent and method of treatment

An antiproliferative, antiinflammatory, antiinfective, immunization agent of a metal ion chelating agent such as picolinic acid, analogs or derivatives thereof, and methods of using the same. The agents chelate metals in metal containing protein complexes and enzymes required for growth, replication or inflammatory response. The preparations can be administered systemically or topically. The products can be used to reduce systemic levels of metals in disease states such as Wilson's disease, iron or lead toxicity. The preparations have antineoplastic, antiviral, antiinflammatory, analgesic antiangiogenic and antiproliferative effects and are used in the treatment of warts, psoriasis, acne, cancers, sunburn, inflammatory responses, untoward angiogenesis and other diseases and in the prevention of sexually transmitted diseases such as genital warts, herpes and AIDS.
Owner:NOVACTYL

Formulations containing hyaluronic acid

InactiveUS6114314AInhibit synthesisQuick to penetrate into skinBiocideSugar derivativesDiseaseActinic keratoses
Topically applied transdermally quick penetrating (best targeting the epidermis and subsequently remaining there for a prolonged period of time) systemic independent acting, combinations and formulations which employ, combine, or incorporate a therapeutically effective non-toxic (to the patient) amount of a drug which inhibits prostaglandin synthesis together with an amount of hyaluronic acid and / or salts thereof (for example the sodium salt) and / or homologues, analogues, derivatives, complexes, esters, fragments, and / or sub units of hyaluronic acid to treat a disease and condition of the skin and exposed tissue for example, basal cell carcinoma, the precancerous, often recurrent, actinic keratoses lesions, fungal lesions, "liver" spots and like lesions (found for the most part in the epidermis), squamous cell tumours, metastatic cancer of the breast to the skin, primary and metastatic melanoma in the skin, genital warts cervical cancer, and HPV (Human Papilloma Virus) including HPV of the cervix, psoriasis (both plaque-type psoriasis and nail bed psoriasis), corns on the feet and hair loss on the head of pregnant women and remain in the skin for a prolonged period of time.
Owner:JAGOTEC AG +1

Compounds and methods for treating tumors, cancer and hyperproliferative diseases

The present invention relates to novel compounds, pharmaceutical compositions and methods for treating tumors, cancer and hyperproliferative diseases including psoriasis, genital warts and hyperproliferative cell growth diseases, including hyperproliferative keratinocyte diseases such as hyperkeratosis, ichthyosis, keratoderma or lichen planus. These compounds are described according to the chemical structure:
  • where R1 is H, OH, F, Cl, Br, I, a C1-C6 optionally substituted alkyl or alkenyl group, an optionally substituted aryl group or a
  •  group;
  • Ra is a H, OH, C1-C10, optionally substituted alkyl or alkenyl group, an optionally substituted O—(C1-C7 alkyl group) or O-aryl group, an amine group which is optionally substituted with at least one C1-C10 alkyl group which may be optionally substituted, or a single optionally substituted aryl group, biphenyl group, (C1-C6) alkylenearyl group, (C1-C6) alkylenebiphenyl group, heteroaryl group, heterocyclic group, (C1-C6) alkylene heteroaryl group or (C1-C6) alkylene heterocyclic group;
  • R2 is a
  •  group;
  • Rb is a H, OH, C1-C10, optionally substituted alkyl or alkenyl group, an optionally substituted O—(C1-C7 alkyl group) or O-aryl group, an amine group which is optionally substituted with at least one C1-C10 alkyl group which may be optionally substituted, or a single optionally substituted aryl group, biphenyl group, (C1-C6) alkylenearyl group, (C1-C6) alkylenebiphenyl group, heteroaryl group, heterocyclic group, (C1-C6) alkylene heteroaryl group or (C1-C6) alkylene heterocyclic group;
  • R3 and R6 are each independently selected from H, OH, F, Cl, Br, I, a C1-C6 optionally substituted alkyl or alkenyl group, an optionally substituted aryl group, a carbamate, alkylene carbamate, urethane or alkylene urethane;
  • R4 is a
  •  group, wherein Rb is as described above; and
  • R5 is a
  •  group, wherein Rb is as described above,
  • with the proviso that at least one of R1 and R2 or R4 and R5 contains an Ra or Rb group which is an amine group which is optionally substituted with at least one C1-C10 alkyl group which may be optionally substituted, or a single optionally substituted aryl group, biphenyl group, (C1-C6) alkylenearyl group, (C1-C6) alkylenebiphenyl group, heteroaryl group, heterocyclic group, (C1-C6) alkylene heteroaryl group or (C1-C6) alkylene heterocyclic group;
  • or a stereoisomer, pharmaceutically acceptable salt, solvate, and polymorph thereof.
Owner:YALE UNIV

Chinese medicine for treating dermatopathy and venereal disease and its preparing process

A Chinese medicine for treating dermatopathy and venereal disease, including eczema, tinea, vulvitis, pointed condyloma, gonorrhea, syphilis etc is prepared from Chinese-medicinal materials including pearl, calomel, realgar, etc through pulverizing and mixing with vasuline. Its advantages are high curative effect, quickly taking its effect, no by-effect and no recurrence.
Owner:任泳橡

Pharmaceutical Formulations for Iontophoretic Delivery of an Immunomodulator

The present invention describes pharmaceutical formulations and methods suitable for iontophoretic delivery of the formulations to a subject. The formulations comprise an immunomodulator, such as imiquimod, and optionally include various agents and excipients. The formulations can be used as a treatment for skin diseases and conditions such as actinic keratosis, basal cell carcinoma and genital warts. The short term iontophoretic delivery of the formulations results in the creation of a depot effect in the skin of the subject, allowing for a sustained delivery. The shortened delivery time minimizes local side effects at the application site.
Owner:NITRIC BIOTHERAPEUTICS INC

HPV (human papillomavirus) peptide/DC (dendritic cell) mixed vaccine and preparation thereof

The invention provides an HPV (human papillomavirus) peptide / DC (dendritic cell) mixed vaccine prepared in the presence of a TLR (toll-like receptor) agonist. The mixed vaccine comprises one part of HPV11E77-15, one part of mouse bone marrow-derived dendritic cells which are cultured in vitro and one part of TLR9 agonist as an adjuvant, wherein the dendritic cells are extracted from mouse bone marrow and further cultured in vitro, the co-incubation with one section of HPV11E7CTL (cytotoxic T lymphocyte) epitope peptide with strongest immunogenicity is firstly carried out, the co-incubation with the TLR ligand CpG and the like is further respectively carried out for promoting the maturation of the DC, the degree of maturation can be confirmed by detecting the change of a marker on the surface of the DC after incubation, and the DC vaccine which is simulated to mature can be used for immunizing mice. The TLR ligand and the HPV11E7 peptide are utilized jointly to promote the degree of maturation of the DC, the level of TNF-alpha (tumor necrosis factor-alpha) and IFN-gamma (immunoreactive fibronectin-gamma) of factors of secretory cells of T cells can be particularly improved after combination of the CpG, and the HPV peptide / DC mixed vaccine can be used for preventing and treating genital warts and cervical cancer.
Owner:ZHEJIANG UNIV

Anus lotion and preparation method thereof

The invention discloses an anus lotion, which is prepared from the following raw materials by weight: 25-35g of radix sophorae flavescentis, 15-25g of cortex phellodendri, 10-20g of radix aconiti preparata, 10-20g of prepared kusnezoff monkshood root, 15-25g of radix angelicae, 25-35g of stephania terandra, 25-35g of dittany bark, 8-12g of dried alum, 12-18g of rheum officinale and 15-25g of gallnut in a manner of decocting after adding water. The anus lotion has the beneficial effects that the anus lotion has the main characteristics of convenience for use and wide pharmacological action, and simultaneously can treat anus diseases with a plurality of concurrent symptoms such as bleeding, pain, pruritus, secretion increase and the like. Clinical application finds that most of haemorrhoids can retract and dissipate as to internal hemorrhoids, inflammatory external hemorrhoids, external hemorrhoids and mixed hemorrhoids at each stage after a patient takes the anus lotion for 5-7 days. Anal eczema can scab and heal after the anus lotion is used for 1-2 weeks while the symptoms are obviously relieved after the patients with anus itching, condyloma acuminata and anal fissure take the anus lotion. Especially for the patient with an anus operation, the anus lotion can relieve swelling and pain, also can purify the wound, reduces the frequency of dressing change, and obviously shortens the wound healing time.
Owner:启东市第五人民医院

Imiquimod vesicle gel and preparation method for same

The invention relates to an imiquimod vesicle gel and a preparation method for the same. The vesicle gel is obtained by preparing a vesicle suspension by using imiquimod and the nonionic surfactants of Brij, Span, Poloxamer and the like via self-assembly, then reacting with the mixed gel matrix of carbomer and povidone, and used for treating the diseases of exophytic genital warts, actinic keratosis, skin basal cancer, melanoma and the like via local application on the skin; and by adding povidone in the carbomer gel matrix, the in-vitro medicine release amount can be increased by 42.1%, thus being beneficial to promote the entrance of medicines in the skin to exert the functions. According to the imiquimod vesicle gel and the preparation method for the same disclosed by the invention, the intradermal retention volume of the medicines in 24 hours can be remarkably increased and is 2.1 times that of the commercially available emulsifiable pastes, and the dose of the medicines penetrating through the skin is reduced by 48.7%; and the equivalent intradermal retention volume can be achieved only by a half of the dose of the commercially available emulsifiable pastes, so that the effectiveness of the medicine effect of the medicated parts can be remarkably enhanced, the dose of the medicines entering in the body can be greatly reduced, and the toxic and side effects of the whole body can be reduced.
Owner:SUZHOU UNIV

Lotion for treating condyloma acuminate and preparation method of lotion

The invention provides a lotion for treating condyloma acuminate and a preparation method of the lotion. The lotion for treating condyloma acuminate is characterized by being prepared from the following components in parts by weight: 30 parts of isatis roots, 30 parts of folium isatidis, 20 parts of houttuynia cordata, 30 parts of honeysuckle, 30 parts of radix sophorae flavescentis, 30 parts of golden cypress, 30 parts of purslane, 20 parts of pearl barley, 20 parts of dried alum, 30 parts of brucea javanica, 10 parts of borax, 20 parts of mint, 0.75 part of fluorouracil and 1500 parts of water. By proportioning cold and cool medicines, the lotion can restrain sarcoma caused by damp and hot, mainly aims to condyloma acuminate, and is matched with fluorouracil. By combination of traditional Chinese and western medicines, the lotion is extremely excellent in effect, high in cure rate, extremely low in recurrence rate, free from oral administration, free from any general side effects, safe and non-toxic, convenient to use and worth clinically applying.
Owner:陈志刚

Chinese herbal compound formulation for treating vulvovaginitis and venereal disease, and preparation method thereof

InactiveCN101411838AGood effectTo achieve the purpose of treating vulvovaginitisHydroxy compound active ingredientsAntiinfectivesDiseasePatrinia
The invention discloses a Chinese medicine compound preparation for treating vulvovaginitis and venereal diseases and a method for preparing the same. The compound preparation is prepared from active ingredients including isatis root, patrinia, glabrous greenbrier rhizome, bugleweed, dyer woad leaves, radix sophorae flavescentis, cicada ecdysis, cnidium fruit, fructus kochiae, radix stemonae, borneol and the like. The method comprises the following steps: besides the borneol, decocting the active ingredients with water for two times, 1.5 hours for each time; filtering the mixture, and combining the filtrate; adding the borneol which is ground into fine powder into the mixture; and then adding 0.2 percent tween 80 for keeping stand, canning the mixture, and performing circulation steam sterilization at a temperature of 100 DEG C for 30 minutes to obtain the finished product. Through applying a mixed lotion of various antibacterial drugs, antiviral drugs and antipruritic drugs, the Chinese medicine compound preparation not only achieves the aim of treating the vulvovaginitis, but also has better effect on treating the venereal diseases such as verruca acuminata, gonococcal vaginitis and the like, and opens up a new way of conservative treatment of the venereal diseases.
Owner:GENERAL HOSPITAL OF THE SECOND ARTILLERY OF CHINESE PLA

Externally-applied medicine for treating moist wart dermatosis and its making method

An exterior-applied Chinese medicine for treating pointed condyloma and dermatopathy is prepared from 10 Chinese-medicinal materials including ginseng, longan aril, honeysuckle flower, coptis root, etc. Its preparing process is also disclosed.
Owner:孟平安
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