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Ointment against virus of human papilloma

An anti-human papilloma and virus technology, applied in the direction of antiviral agents, medical raw materials derived from arthropods, medical preparations containing active ingredients, etc., can solve the problem of being inferior to podophyllum lipid solution, expensive, and tissue destructive and other problems, to achieve the effect of rich drug sources, low price and wide application

Inactive Publication Date: 2003-11-19
哈尔滨医科大学附属第一临床医学院 +3
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

This medicine has a history of more than 50 years. It is used to treat venereal warts. The total effective rate of its curative effect is 40-85%. There is no production in my country at present, and it depends on imports. It is expensive and destructive to normal tissues around the lesion. Excessive or inappropriate can cause systemic toxic reactions, mainly manifested as nausea, vomiting, fever, recurrent neuritis, leukopenia and thrombocytopenia, and fetal malformation
The 5-fluorouracil ointment produced in my country is far inferior to that of podophyllum lipid solution. At present, physical therapy is often used for treatment, such as: freezing, laser, electrocautery, etc. The above-mentioned treatments are limited by special equipment and other conditions, so it is inconvenient to use

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0029] Arsenic stone 0.8 Distilled water 49

[0030] Brucea javanica 1.8 Monoglyceride 5.0

[0031] Lead lead 1.0 Glycerin 10

[0032] Galla 2.3 Vaseline 5.0

[0033] Cork 14 Hard Acid 10.7

[0034] Borneol 0.1 Triethanolamine 0.3

Embodiment 2

[0036] Arsenic stone 0.9 Distilled water 49

[0037] Brucea javanica 0.9 Monoglyceride 6.0

[0038] Lead lead 1.2 Glycerin 10

[0039] Gallnut 1.8 Vaseline 5.7

[0040] Cork 13 Hard Acid 11

[0041] Borneol 0.2 Triethanolamine 0.3

Embodiment 3

[0043] Arsenicite 1.8 Distilled water 49

[0044] Brucea javanica 0.6 Monoglyceride 5.0

[0045] Red lead 1.4 Glycerin 10.7

[0046] Galla 2.1 Vaseline 5.0

[0047] Cork 14 Hard Acid 10

[0048] Borneol 0.1 Triethanolamine 0.3

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Abstract

A human papillomavirus (HPV)-resistant ointment for treating the wart of vulva, vagina and cervix, the black lesion of vulva, and pointed condylona caused by HPV is prepared from 12 raw materials including brucea fruit, Chinese gall, glycerine, monoglyceride, etc. Its advantages are high curative effect and no irritation to skin.

Description

Technical field [0001] The invention belongs to a traditional Chinese medicine formula, in particular to an antiviral ointment for treating genital warts caused by viruses. Background technique [0002] Genital warts infected by human papillary virus (HPV) are one of common sexually transmitted diseases (STDs), and the incidence rate has risen rapidly at home and abroad in the past ten years. According to the statistics of the United Kingdom in 1984, the disease increased by 10% compared with 10 years ago. According to the survey of private doctors in the United States, STDs have increased by 450% in the last 15 years, among which viral diseases are the first. Surveillance statistics of STDs in 16 cities in China were collected from 1987 to 1989, among which genital warts increased rapidly, with an average annual growth rate of 136.32%. Babies have a tendency to cause fetal malformations. Domestic and foreign literature reports that HPV16 and HPV18 are closely related to th...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K35/64A61P31/12
Inventor 朱桂纯董秀兰温雪松朱春英赵淑贞
Owner 哈尔滨医科大学附属第一临床医学院
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