Patents
Literature
Hiro is an intelligent assistant for R&D personnel, combined with Patent DNA, to facilitate innovative research.
Hiro

1685 results about "Cultured cell" patented technology

Essentially, cell culture involves the distribution of cells in an artificial environment (in vitro) which is composed of the necessary nutrients, ideal temperature, gases, pH and humidity to allow the cells to grow and proliferate. In vivo - When the study involves living biological entities within the organism.

Adipose-derived stem cells and lattices

The present invention provides adipose-derived stem cells and lattices. In one aspect, the present invention provides a lipo-derived stem cell substantially free of adipocytes and red blood cells and clonal populations of connective tissue stem cells. The invention also provides a method of isolating stem cells from adipose tissues. The cells can be employed, alone or within biologically-compatible compositions, to generate differentiated tissues and structures, both in vivo and in vitro. Additionally, the cells can be expanded and cultured to produce hormones and to provide conditioned culture media for supporting the growth and expansion of other cell populations. In another aspect, the present invention provides a lipo-derived lattice substantially devoid of cells, which includes extracellular matrix material from adipose tissue. The lattice can be used as a substrate to facilitate the growth and differentiation of cells, whether in vivo or in vitro, into anlagen or even mature tissues or structures.
Owner:UNIVERSITY OF PITTSBURGH +1

Non-tumorigenic MDCK cell line for propagating viruses

The present invention provides novel MDCK-derived adherent non-tumorigenic cell lines that can be grown in the presence or absence of serum. The cell lines of the present invention are useful for the production of vaccine material (e.g., viruses). More specifically, the cell lines of the present invention are useful for the production of influenza viruses in general and ca / ts influenza viruses in particular. The invention further provides methods and media formulations for the adaptation and cultivation of MDCK cells such that they remain non-tumorigenic. Additionally, the present invention provides methods for the production of vaccine material (e.g., influenza virus) in the novel cell lines of the invention.
Owner:MEDIMMUNE LLC

Method for producing biodiesel by autotrophic culture and heterotrophic culture of chlorella

The invention discloses a method for producing biological diesel oil by two steps of culture of chlorellas, namely, autotrophy and heterotrophy, which belongs to the renewable biological energy field. Concentrated autotrophic algae is put into a fermentation tank to perform heterotrophic growth from the processes of autotrophic culture, cell concentration and fermentation pollution controlling of the chlorellas, to ensure the chlorellas to be synthesized into neutral fat. Effective feeding strategy is established to ensure the fat to be synthesized into optimal after the optimization of the fermentation conditions and the process control. The biomass can reach 108g.L-1, and the grease content can reach 52 percent of cell dry weight. After the culturing is finished, biological diesel oil can be prepared after extracting algal oil and transesterification reaction. The cell concentration technology adopted by the invention can effectively avoid the problem of light restriction during the high density culture process Not only is the carbon dioxide emission reduced, but also the organic carbon source consumption is reduced, thus the preparation cost of the biological diesel oil material is saved. The whole technical line is environmental friendly, high efficient, and can meet the industrial application requirements of the microalgae biological diesel oil.
Owner:TSINGHUA UNIV

Method for preparing cell cultures from biological specimens for chemotherapeutic and other assays

An improved system for screening a multiple of candidate therapeutic or chemotherapeutic agents for efficacy as to a specific patient, in which a tissue sample from the patient is harvested, cultured and separately exposed to a plurality of treatments and/or therapeutic agents for the purpose of objectively identifying the best treatment or agent for the particular patient. Specific method innovations such as tissue sample preparation techniques render this method practically as well as theoretically useful. One particularly important tissue sample preparation technique is the initial preparation of cohesive multicellular particulates of the tissue sample, rather than enzymatically dissociated cell suspensions or preparations, for initial tissue culture monolayer preparation. With respect to the culturing of malignant cells, for example, it is believed (without any intention of being bound by the theory) that by maintaining the malignant cells within a multicellular particulate of the originating tissue, growth of the malignant cells themselves is facilitated versus the overgrowth of fibroblasts or other cells which tends to occur when suspended tumor cells are grown in culture. Practical monolayers of cells may thus be formed to enable meaningful screening of a plurality of treatments and/or agents. Growth of cells is monitored to ascertain the time to initiate the assay and to determine the growth rate of the cultured cells; sequence and timing of drug addition is also monitored and optimized. By subjecting uniform samples of cells to a wide variety of active agents (and concentrations thereof), the most promising agent and concentration for treatment of a particular patient can be determined. For assays concerning cancer treatment, a two-stage evaluation is contemplated in which both acute cytotoxic and longer term inhibitory effect of a given anti-cancer agent are investigated.
Owner:PRECISION THERAPEUTICS
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products