The invention relates to the field of industrial automation virtual simulation, in particular to a mixed collision detection method based on a convex hull and pre-judgment, which comprises the following steps of: 1, setting a similar-to-sphere threshold value and an inclined included angle threshold value; 2, calculating a convex hull of a model by using a rapid convex hull algorithm, and calculating a central position of a bounding box and a model similar-to-sphere rate according to the convex hull of the model; 3, when the similar-to-sphere rate is smaller than the similar-to-sphere threshold value, adopting an SBB; otherwise, calculating the inclined included angle of the model, and if the inclined included angle is smaller than the inclined included angle threshold value, selecting an AABB; when the inclined included angle is greater than the inclined included angle threshold value, selecting an OBB; and 4, carrying out intersection test on the bounding boxes. According to the method, the appropriate bounding box type can be selected based on the convex hull characteristics of models, the intersection test efficiency is improved, and the tightness of constructed bounding boxes is better.