60 results about "Cardiac electrophysiology" patented technology

A method and system for estimating physiological heart measurements from medical images and clinical data disclosed. A patient-specific anatomical model of the heart is generated from medical image data of the patient. A patient-specific multi-physics computational heart model is generated based on the patient-specific anatomical model by personalizing parameters of a cardiac electrophysiology model, a cardiac biomechanics model, and a cardiac hemodynamics model based on medical image data and clinical measurements of the patient. Cardiac function of the patient is simulated using the patient-specific multi-physics computational heart model. The parameters can be personalized by inverse problem algorithms based on forward model simulations or the parameters can be personalized using a machine-learning based statistical model.

The present invention refers to the field of cardiac electrophysiology (EP) and, more specifically, to image-guided radio frequency ablation and pacemaker placement procedures. For those procedures, it is proposed to display the overlaid 2D navigation motions of an interventional tool intraoperatively obtained from the same projection angle for tracking navigation motions of an interventional tool during an image-guided intervention procedure while being navigated through a patient's bifurcated coronary vessel or cardiac chambers anatomy in order to guide e.g. a cardiovascular catheter to a target structure or lesion in a cardiac vessel segment of the patient's coronary venous tree or to a region of interest within the myocard. In such a way, a dynamically enriched 2D reconstruction of the patient's anatomy is obtained while moving the interventional instrument. By applying a cardiac and / or respiratory gating technique, it can be provided that the 2D live images are acquired during the same phases of the patient's cardiac and / or respiratory cycles. Compared to prior-art solutions which are based on a registration and fusion of image data independently acquired by two distinct imaging modalities, the accuracy of the two-dimensionally reconstructed anatomy is significantly enhanced.

Disclosed is an expandable transluminal sheath, for introduction into the body while in a first, low cross-sectional area configuration, and subsequent expansion of at least a part of the distal end of the sheath to a second, enlarged cross-sectional configuration. The distal end of the sheath is maintained in the first, low cross-sectional configuration and expanded using a radial dilatation device. In an exemplary application, the sheath is utilized to provide access for diagnostic or therapeutic procedures such as ureteroscopy, cardiac electrophysiology, gastroenterology, and spinal access.

A method and system for image-based patient-specific guidance of cardiac arrhythmia therapies is disclosed. A patient-specific anatomical heart model is generated from medical image data of a patient. A patient-specific cardiac electrophysiology model is generated based on the patient-specific anatomical heart model and electrophysiology measurements of the patient. One or more virtual electrophysiological interventions are performed using the patient-specific cardiac electrophysiology model. One or more pacing targets or ablation targets based on the one or more virtual electrophysiological interventions are displayed.