The invention provides a method for preparing tobacco flavor with caprylic capric triglyceride and application of the tobacco flavor to cigarette bead blasting. The preparing method mainly includes the following steps that (1) natural plant raw materials are dried, smashed and sieved to be prepared into solid powder; (2) natural plant solid powder, the caprylic capric triglyceride and a vitamin Eare subjected to heating reflux extraction, rough filtration is carried out with gauze, then filtering is carried out with a microfiltration membrane, impurities and a small quantity of un-dissolved substances are removed, and the tobacco flavor is obtained. The method is simple in technology, easy to control and low in raw material cost; a prepared flavor product has the natural, pure and harmonious fragrance characteristics, the natural feeling is high, the product quality is stable, the tobacco flavor serves as an oil-solubility content and can be directly applied to a cigarette bead blasting core material, the online forming effect of bead blasting is stable, and meanwhile the tobacco flavor has the effect of removing the content of free radicals in cigarette mainstream smoke in the cigarette burning smoking process.