32 results about "Bupleurum scorzonerifolium" patented technology

A method for extracting antineoplastic component from Bupleurum scorzonerifolium applicable in treating cell proliferative disorder is proposed. The antineoplastic components of Bupleurum scorzonerifolium include at least a Y-butyolactone centred heterocyclic compound with a Z configuration or E configuration at its carbon 2(5) position, and molecules, such as Chaihulactone, Isochaihulactone, Chaihulactone analogues or derivatives containing in the heterocyclic compound. From results of cell and molecular biological studies, in vivo animal test, and histological study, it is found that antineoplastic components extracted from Bupleurum scorzonerifolium are effective in suppressing a variety of cancer cell growths, inhibiting telomerase activity, as well as effective in killing with high specificity Taxol-resistant tumor cells at later stage of chemical therapy, making the components a new choice for anti-cancer agent, anti-HIV agent, or synergistic agent.

The invention relates to a preparation process of integration-type novel formulation of DACHAIHU decoction and a production method thereof. The effective components of the novel formulation are made from the following raw materials (by weight parts): Radix Bupleuri (Bupleurum chinense and / or Bupleurum scorzonerifolium) 15, Scutellaria baicalensis 9, Paeonia lactiflora 9, Pinellia ternate 9, Zingiber officinale 15, Fructus Aurantii Immaturus (Citrus aurantium and / or Citrus sinensis) 9, Ziziphus jujuba (Fructus Jujubae) 4 and Radix Et Rhizoma Rhei 6. The production method includes the steps of supersonic airstream pulverization, alcohol-water extraction, ultrasonic pulverization and extraction, water decoction and concentration, supersonic spray-drying, nano-scale grinding, high-pressure emulsion and homogenization and nanoparticle preparation. The production method integrates the advantageous of the nano-carrier combination technique, such as multi-component synergism and multi-target. The large-scale production can greatly reduce the production cost, greatly improve the product quality and enhance the target property and sustained / controlled-release property of drugs. The novel formulation is administered by oral intake and external application during four time periods respectively based on the midnight-noon tidal flow and human qi-blood flow rule. The novel formulation is also processed to membranes and transdermal delivery agents which are applied to different parts of human body respectively according to the midnight-noon tidal flow and human qi-blood flow rule and can be directly absorbed by the skin.

The invention relates to a traditional Chinese medicine for treating cold in children, which is characterized by mainly comprising components of 12g of Bupleurum scorzonerifolium, 12g of radices scutellariae, 10g of chrysanthemum, 9g of radices isatidis seu baphicacanthi, 12g of Matricaria indica, 9g of fructus forsythiae, 9g of balloon flower, 9g of radices stemonae, 9g of raw liquorice, and the like. The medicine is prepared by a preparation method as follows: the components are put in a container, dipped with water for 30min, decocted with slow fire for 30min and filtered to take liquid of 100ml, the liquid is taken after meal and is taken by one dose every other day, and three doses are taken as one course of the treatment of the medicine. The medicine is purely prepared from traditional Chinese medicines by a traditional preparation method, maintains the medicinal properties of the medicines, has the effects of dispelling wind and heat, relieving internal heat or fever, expelling phlegm and arresting coughing, achieves the purpose of treatment and has no side effect.

A traditional Chinese medicine for treating climacteric syndrome is prepared from the following medicinal materials: Rehmannia glutinosa, Salvia miltiorrhiza, blighted wheat, Ziziphus jujuba (Fructus Jujubae), Curculigo orchioides, Herba Epimedii, Radix Bupleuri (Bupleurum chinense and / or Bupleurum scorzonerifolium), Angelica sinensis, Paeonia lactiflora (Radix Paeoniae Alba), Poria cocos, Atractylodes macrocephala, Glycyrrhiza uralensis and Morinda officinalis. The first dose of the above medicinal materials are decocted in 700 mL of water to 200 mL, and the second dose of the above medicinal materials are decocted in 500 mL of water to 200 mL. The traditional Chinese medicine is taken twice a day at morning and night on an empty stomach.

The invention provides a method for converting and synthesizing saponin through adventitious root system culture of Chinese thorowax root. The method comprises the following steps of: sterilization of an explant; induction and proliferation of callus; differentiation and induction of an adventitious root; proliferation of the adventitious root and forming of an adventitious root system; and biosynthesis and conversion of saikosaponin. The invention is characterized by selecting the undercutting section of honewort or bupleurum scorzonerifolium willd as the explant and screening the culture medium compositions for inducing the callus, the induced conditions of the adventitious root, the culture medium compositions of adventitious root proliferation and adventitious root system forming and a culture medium for converting and synthesizing the saikosaponin. The culture medium has good acceleration effect on the adventitious root proliferation, the adventitious root system forming and the saponin synthesis. The maximum monthly proliferation ratio of the adventitious root can reach 10.554, the maximum monthly dry weight proliferation multiple thereof can reach 10.352, and the maximum total amount of the saikosaponin a and d can reach 0.149 percent.

The invention relates to a pure component traditional Chinese medicinal formulation for treating functional dyspepsia, which is prepared by taking Radix Bupleuri (Bupleurum chinense and / or Bupleurum scorzonerifolium), Paeonia lactiflora (Radix Paeoniae Alba), Cyperus rotundus, Atractylodes macrocephala, Melia toosendan fruit, Flos Inulae (Inula japonica and / or Inula britannica), Fructus Aurantii Immaturus (Citrus aurantium and / or Citrus sinensis) and Corydalis yanhusuo as a basic prescription, extracting a component A which uses volatile oil as a main ingredient, a component B which uses sesquiterpene lactone as main ingredient, a component C which uses alkaloid as a main ingredient, a component D which uses flavone as a main ingredient, a component E which uses saponin as a main ingredient and a component F which uses polysaccharide as a main ingredient from the basic prescription with a flash extraction technology, wherein the traditional Chinese medicinal formulation comprises the following components in parts by weight: 5-35 parts of the component A, 5-35 parts of the component B, 5-45 parts of component C, D 5-40 parts of the component D , 10-25 parts of the component E, and 5-40 parts of the component F. The traditional Chinese medicinal formulation is used for treating functional dyspepsia which belongs to liver-stomach disharmony in traditional Chinese medicine with symptoms of stomach duct swelling and pain, pain action or pain worse in case of worry, pain relief after belching and intestinal flatus from anus, chest distress, belching, inhibited defecation, thin and white tongue, and wiry pulse.

The invention provides a method for detecting bupleurum chinense and bupleurum scorzonerifolium by utilizing a specific primer PCR (polymerase chain reaction). According to the method, a specific primer capable of rapidly detecting the bupleurum chinense and the bupleurum scorzonerifolium based on ITS (Internal Transcribed Spacer) sequences of the bupleurum chinense and the bupleurum scorzonerifolium is designed, and a PCR detection system is established based on the specific primer to respectively amplify PCR fragments of 336 bp and 407 bp, so that the molecular identification basis is provided for the medicinal material identification of the bupleurum chinense and the bupleurum scorzonerifolium and whether multiple Chinese patent medicines (honeyed pills and water-honeyed pills) and medicinal materials contain the bupleurum chinense and the bupleurum scorzonerifolium can be rapidly and accurately detected; a detection kit constructed according to the method has the advantages that the operation is simple and convenient, the specificity is good, the sensitivity is high, the sequencing is omitted and the like, and the detection to stems and leaves of the bupleurum chinense and the bupleurum scorzonerifolium or other parts of plants and to the medicinal materials and the Chinese patent medicines (honeyed pills and water-honeyed pills) can be realized.

A pharmaceutical composition with an immunomodulating function is provided, including an extract of Bupleurum obtained by grinding the Bupleurum, adding the ground Bupleurum to a solvent and isolating the extract from the solvent, wherein the Bupleurum comprises Bupleurum krlovianum, Bupleurum longiradiatum, Bupleurum smithii, Bupleurum pusillum, Bupleurum longicaule, Bupleurum salicifolium, Bupleurum scorzonerifolium and Bupleurums with at least one of the nucleotide sequences selected from a group consisting of SEQ ID NOs. 1˜6 and a nucleotide sequence with no more than 1% of the nucleotide sequence divergences of SEQ ID NOs. 1˜6, or combinations thereof.

The invention discloses a primer set, a probe composition, a kit and a detection method for simultaneous identification of bupleurum scorzonerifolium and bupleurum chinense and application. According to the invention, specific primers of bupleurum scorzonerifolium and bupleurum chinense are employed for PCR amplification of a DNA extract of a to-be-detected sample, bupleurum universal primers are designed as the quality control, accurate target sites are provided for detection and identification of genuine bupleurum scorzonerifolium and bupleurum chinense, thus achieving fast and accurate identification. The detection method provided by the invention is simple, quick and effective, and can quickly and accurately identify the components of the genuine bupleurum scorzonerifolium and bupleurum chinense.

The invention relates to the technical field of traditional Chinese medicine detection, in particular to a bupleurum DNA (deoxyribonucleic acid) identifying kit and identifying method. The identifying kit comprises a DNA extraction reagent, a bupleurum identifying system and a bupleurum scorzonerifolium willd identifying system. The bupleurum DNA identifying method comprises the steps of: designing two pairs of specific oligonucleotide primers of the bupleurum ribosomal DNA, artificially synthesizing two pairs of primers, establishing a bupleurum DNA identifying kit, determining a reaction process, judging the result, and the like. The bupleurum DNA identifying kit and identifying method can be used for identifying and detecting traditional Chinese medicines, the bupleurum DNA identifying kit can accurately identify the specificity of bupleurum and can simultaneously identify the bupleurum, the bupleurum scorzonerifolium willd and confusing species thereof, and the identifying method has the advantages of simplicity, quickness and the like.

The invention relates to a bupleurum chinense intraspecific or interspecific hybridization technology, in particular to a bupleurum chinense hybridization technology overcoming seed production difficulties in a high-rainfall region. Bupleurum chinense is a cross-pollination plant, a serious germplasm mixing and variety degeneration phenomenon is prone to be caused by nonstandard seed reproduction, and meanwhile due to long-term system seed selection, high-yield, efficient and high-adaptability seed selection of the bupleurum chinense is confronted with bottlenecks. In the high-rainfall region, bupleurum chinense hybridization and seed harvesting cannot be normally achieved through the conventional field castration, bagging and pollination technology. The technology comprises the following steps of 1, bupleurum chinense seedling growing; 2, plant management; 3, castration; 4, pollination; 5, seed harvesting. The breeding cycle is greatly shortened, and the problem that bupleurum chinense seed production in the high-rainfall region is difficult is solved; in addition, the technology cannot cause branch breakage caused by too heavy bagging and is widely suitable for intraspecific and interspecific hybridization of the bupleurum chinense varieties including bupleurum chinense, bupleurum scorzonerifolium, bupleurum marginatum and bupleurum falcatum.

The invention provides a traditional Chinese medicinal composition for eliminating mammary swelling, which is prepared from the following traditional Chinese medicinal materials: Isatis indigotica root, Olibanum, Houttuynia cordata, Cyathula officinalis, Fructus Trichosanthis (Trichosanthes kirilowii and / or Trichosanthes rosthornii), Anemarrhena asphodeloides, Crocus sativus flower, Rhizoma Curcumae, Euryale ferox seed, Radix Bupleuri (Bupleurum chinense and / or Bupleurum scorzonerifolium), Liquidambar formosana, Gardenia jasminoides fruit, Angelica sinensis, Radix Paeoniae Rubra (Paeonia lactiflora and / or Paeonia veitchii), Polygonum multiflorum stem, Semen Phaseoli (Phaseolus calcaratus and / or Phaseolus angularis), Codonopsis lanceolata root, Astragalus membranaceus, Marsdenia tenacissima stem, Elephantopus scaber, Leonurus japonicus, Lycopodium japonicum, Morus alba bark, and Bulbophyllum inconspicuum. The traditional Chinese medicinal composition has effects of improving microcirculation, clearing lactiferous ducts, promoting milk secretion, reducing milk block deposition, relieving pain in lactation, relieving breast pain, promoting postpartum lactation and increasing maternal feeding rate, and has low price and no toxic and adverse side effect.

The invention provides a traditional Chinese medicine composition for treating hyperplasia of mammary glands and a preparation method thereof, which belong to the technical field of traditional Chinese medicine. The traditional Chinese medicine composition comprises the following raw materials in parts by weight: 15-30 parts of Serissa japonica, 5-10 parts of patrinia herb, 5-20 parts of castor bean, 3-11 parts of dragons blood, 2-10 parts of caudate sweetleaf leaf, 2-10 parts of bindweed, 10-15 parts of spatholobus stem, 10-15 parts of curcuma rhizome, 10-15 parts of cochinchia momordica seed, 7-11 parts of dill seeds, 9-21 parts of bupleurum scorzonerifolium willd, 10-30 parts of toosendan fruit, 15-20 parts of Cyperus Rotundus L, 10-15 parts of laminaria japonica, 1-5 parts of seed of cowherb, and 1-5 parts of liquidambar formosana hance. The traditional Chinese medicine composition is used for treating hyperplasia of mammary glands by principles of relieving depression and dissipating binds, regulating meridian, and removing stasis and nucleus, and has the advantages of fast effectiveness, good curative effect, and no toxic and side effect.

The invention belongs to a medicine for treating neurodegenerative disease, and concretely relates to an application of radix bupleuri volatile oil in preparation of the medicine for treating neurodegenerative disease. According to the invention, neurodegenerative diseases mean Alzheimer's disease, Parkinson disease, multiple sclerosis and Huntington's disease. The radix bupleuri volatile oil is the volatile oil extracted from Bupleurum chinense DC. or Bupleurum scorzonerifolium Willd. The radix bupleuri volatile oil can obviously inhibit release of microglial cell inflammatory factors NO and ROS induced by lipopolysaccharide (LPS); and the test result shows that the radix bupleuri volatile oil has obvious protection effect for AD mice learning-memory impairment induced by LPS.

The invention discloses a seedling growing method for enhancing emergence rate of Bupleurum chinense / Bupleurum scorzonerifolium, and belongs to the field of breeding and cultivation of traditional Chinese medicinal materials. The method includes the following steps: (1) performing pre-treatment; (2) performing sand storage treatment; (3) performing coating treatment; (4) performing seedling growing in a greenhouse; and (5) performing field transplanting. The method can treat Bupleurum chinense / Bupleurum scorzonerifolium seeds before seedling growing, so that seed dormancy can be broken as soonas possible, germination rates and seedling rates can be enhanced, neat emergence can be achieved, and the period of emergence can be shortened; and through root dipping treatment before transplanting, the growth and development of roots under the ground can be promoted, bolting rates can be decreased, and the root yield of Bupleurum chinense / Bupleurum scorzonerifolium can be increased.

The invention discloses traditional Chinese medicine powder for treating wind-cold influenza. Each bag of the traditional Chinese medicine powder comprises the following raw materials by weight: 20g-40g of herba schizonepetae, 2g-8g of radix saposhnikoviae, 2g-8g of mint, 1g-6g of rhizoma kaempferiae, 3g-12g of bupleurum scorzonerifolium and 3g-12g of radix stellariae. The traditional Chinese medicine powder is a pure traditional Chinese medicine preparation, has a creative formula and remarkable treating effect, is in strict accordance with a formulating prescription of 'monarch, minister, assistant and guide', has the efficacies of repelling cold, helping digestion, invigorating stomach, relieving cough and bringing down fever, can rapidly take effect for treating wind-cold influenza, is short in treatment course and safe and has no toxic or side effects, and the wind-cold influenza is difficult to relapse; the traditional Chinese medicine powder is economical and practical and is worthy of being widely generalized, and the treatment time is saved.

The invention relates to a Chinese medicinal decoction for treating endometriosis type infertility and a preparation method of the decoction, belonging to a compound Chinese medicinal decoction of Chinese medicinal technical field. The decoction comprises the following components by weight percentage: 9-12g of Radix Bupleuri (Bupleurum chinense and / or Bupleurum scorzonerifolium), 10-15g of Angelica sinensis, 10-15g of Red Peony Root and 10-15g of White Peony Root, 10-30g of Sparganium stoloniferum, 10-30g of Rhizoma Curcumae, 10-30g of Astragalus membranaceus, 10-30g of gizzard membrane of Gallus gallus domesticus, 10-30g of Gleditsia sinensis thorn, 6-10g of Leeches, 10-30g of Lycopus lucidus, 10-15g of processed Cyperus rotundus, 10-30g of Dipsacus asperoides, 10-30g of Drynaria fortunei, 10-30g of Eucommia ulmoides, 10-15g of Morinda officinalis and 6-15g of deerhorn pieces. The preparation method comprises the following steps: putting the above Chinese medicinal materials into a decocting appliance, adding clean water meeting a standard of drinking water, and allowing the water surface to be higher than the medicinal materials by 2-4cm; soaking for 25-35 minutes, boiling with strong fire; decocting with slow fire for 20-30 minutes after boiling; and removing dregs to obtain the decoction. The Chinese medicinal decoction of the invention has the functions of promoting bloodcirculation and removing blood stasis, stopping pain and dispersing accumulation, enriching and tonifying Qi, promoting diuresis and removing sputum and tonifying kidney and strengthening yang, and is beneficial to the sperm-egg binding to help gestation so as to be applied to patients with endometriosis type infertility.

The invention relates to the field of medicinal preparations, particularly relates to a traditional Chinese medicinal decoction for treating scarlet fever, which is prepared from the following raw materials in percentage by weight: 7-10% of Arctium lappa fruit, 4-7% of Radix Bupleuri (Bupleurum chinense and / or Bupleurum scorzonerifolium), 4-6% of Physalis alkekengi, 4-7% of Herba Dendrobii, 5-8% of Scutellaria baicalensis, 4-6% of Polygonatum odoratum, 3-6% of Belamcanda chinensis, 4-6% of Gardenia jasminoides fruit, 2-3% of Cortex Moutan Radicis, 3-5% of Rehmannia glutinosa, 4-7% of Spirodela polyrrhiza, 6-9% of Cannabis sativa seed, 5-8% of Ophiopogon japonicus, 4-6% of Prunella vulgaris, 7-9% of Forsythia suspensa, 5-7% of Scrophularia ningpoensis, and 2-5% of Flos Lonicerae. The preparation method of the traditional Chinese medicinal decoction includes soaking the above raw materials in water, decocting, filtering to remove residues, and collecting filtrate. The traditional Chinese medicinal decoction can treat scarlatina, has the advantages of high efficacy, no allergic or toxic reaction, and no adverse side effect, can treat scarlet fever with high therapeutic effect and can prevent allergic reactions.

The invention discloses a rice seedling growing tray which is prepared according to the method comprising the following steps: (1) dosing plant straws, chicken manure, bean pulp, shrimp shells, diatomite, zeolite powder, weathering coral, 25-35 parts of black false hellebore, rheum officinale, fructus kochiae, polygonum cuspidatum, carpesium abrotanoides, Bupleurum scorzonerifolium, Hedyotis biflora, castor bean, pokeberry root, rhizome of dryopteris, rhizoma galangae, loquat root, aspongopus and scirpus maritimus; (2) fermenting the plant straws, chicken manure, bean pulp and shrimp shells; (3) sintering the weathering coral; (4) dissolving the sintered substance in water, mixing with zeolite powder, and irradiating by using far infrared rays; (5) decocting the traditional Chinese medicines to obtain the filtrate; (6) soaking the diatomite in the decocted filtrate; (7) uniformly mixing the materials obtained in the previous steps; and (8) performing compression molding. According to the seedling growing tray, the rice yield can be improved, the plant diseases and insect pests are controlled, and the ratio of lysine in proteins can be improved, so that the quality and taste of the rice are improved.

The invention discloses a folium mori moxibustion formula and use thereof, and relates to the technical field of traditional Chinese medicine formulae. The folium mori moxibustion formula comprises the following raw materials: folium artemisiae argyi, folium mori, folium eupatorium adenophorum, pericarpium citri reticulatae, radix puerariae, herba hyperici perforati cum radice, caulis et folium nepenthis mirabilis, folium lantanae camarae, herba patriniae, cortex salicis altae, cortex pinus massoniana lamb, herba andrographis, radix bupleurum scorzonerifolium willd, melaleuca altemifolia oil,caryophyllus oil, herba chelidonii extract, bulbus allii extract, semen sojae extract and modified fillers. The folium mori moxibustion formula is simple and convenient to prepare, significant in efficacy, free of side effects and good in health preservation and health caring effects.

The present invention relates to the field of medicines, is named as application of radix bupleuri and herba houttuyniae in preparation of medicines for prevention and treatment of ionising radiation damage, and discloses application a combination of two pure traditional Chinese medicine preparations of bupleurum chinense or bupleurum scorzonerifolium total extract and herba houttuyniae extract in preparation of medicines for prevention and treatment of ionising radiation damage. The invention discloses that the radix bupleuri extract and the herba houttuyniae extract can play a radiation protective effect in cell and living animal levels, and has a protective effect in a wide dose range comprising lethal dose, sub-lethal dose and low dose radiation, the combination of the two active extracts is better than single use of the extracts, the combination is low in cost and wide in sources, and can be used for preparation of the medicines for prevention and treatment of ionising radiation-caused relative damages and diseases.

The invention relates to a Chinese medicinal decoction for treating endometriosis type infertility and a preparation method of the decoction, belonging to a compound Chinese medicinal decoction of Chinese medicinal technical field. The decoction comprises the following components by weight percentage: 9-12g of Radix Bupleuri (Bupleurum chinense and / or Bupleurum scorzonerifolium), 10-15g of Angelica sinensis, 10-15g of Red Peony Root and 10-15g of White Peony Root, 10-30g of Sparganium stoloniferum, 10-30g of Rhizoma Curcumae, 10-30g of Astragalus membranaceus, 10-30g of gizzard membrane of Gallus gallus domesticus, 10-30g of Gleditsia sinensis thorn, 6-10g of Leeches, 10-30g of Lycopus lucidus, 10-15g of processed Cyperus rotundus, 10-30g of Dipsacus asperoides, 10-30g of Drynaria fortunei, 10-30g of Eucommia ulmoides, 10-15g of Morinda officinalis and 6-15g of deerhorn pieces. The preparation method comprises the following steps: putting the above Chinese medicinal materials into a decocting appliance, adding clean water meeting a standard of drinking water, and allowing the water surface to be higher than the medicinal materials by 2-4cm; soaking for 25-35 minutes, boiling with strong fire; decocting with slow fire for 20-30 minutes after boiling; and removing dregs to obtain the decoction. The Chinese medicinal decoction of the invention has the functions of promoting bloodcirculation and removing blood stasis, stopping pain and dispersing accumulation, enriching and tonifying Qi, promoting diuresis and removing sputum and tonifying kidney and strengthening yang, and is beneficial to the sperm-egg binding to help gestation so as to be applied to patients with endometriosis type infertility.

The invention provides a method for converting and synthesizing saponin through adventitious root system culture of Chinese thorowax root. The method comprises the following steps of: sterilization of an explant; induction and proliferation of callus; differentiation and induction of an adventitious root; proliferation of the adventitious root and forming of an adventitious root system; and biosynthesis and conversion of saikosaponin. The invention is characterized by selecting the undercutting section of honewort or bupleurum scorzonerifolium willd as the explant and screening the culture medium compositions for inducing the callus, the induced conditions of the adventitious root, the culture medium compositions of adventitious root proliferation and adventitious root system forming and a culture medium for converting and synthesizing the saikosaponin. The culture medium has good acceleration effect on the adventitious root proliferation, the adventitious root system forming and the saponin synthesis. The maximum monthly proliferation ratio of the adventitious root can reach 10.554, the maximum monthly dry weight proliferation multiple thereof can reach 10.352, and the maximum total amount of the saikosaponin a and d can reach 0.149 percent.

The invention relates to the field of medicines, discloses the application of Bupleurum Chinese and Shenmai on the aspect of preparation of a medicine for preventing and treating ionization radiation injuries, and particularly discloses the application of the combination of the two pure traditional Chinese preparations of a total extract of Bupleurum Chinese or Bupleurum scorzonerifolium and a red ginseng and radix ophiopogonis extract (a Shenmai injection) on the aspect of preparation of the medicine for preventing and treating ionization radiation injuries. According to the application, the extract of Bupleurum Chinese and the Shenmai injection play the radiation protection role on the cell level and the animal living body level, the protective effect is achieved within the wide dosage range of the lethal dosage, sub-lethal dosage and low dosage radiation, the combination of the two medicines is better than independent use of the medicines, and the application is low in combination cost, has extensive sources, and can be used for preparing the medicine for preventing and treating related injuries caused by ionization radiation and treating diseases.

The invention discloses a traditional Chinese medicine preparation for treating breast hyperplasia. The preparation is composed of the following active pharmaceutical ingredients of, by weight, 5-15 parts of cinnamon, 5-15 parts of fennel fruit, 3-9 parts of bupleurum scorzonerifolium willd, 3-9 parts of pericarpium citri reticulatae viride, 3-9 parts of pericarpium citri reticulatae, 5-15 parts of rhizoma chuanxiong, 5-15 parts of radix paeoniae rubra, 5-15 parts of raw white mustard seed, 5-15 parts of aiomatic turmeric root-tuber, 5-15 parts of zhi cyperus rotundus, 3-9 parts of fructus amomi and 3-9 parts of borneol. The traditional Chinese medicine preparation is prepared by taking all the active pharmaceutical ingredients, mixing, smashing into medicine powder and sieving with 200 meshes. When the preparation is in use, the medicine powder is loaded in a 10 cm*10 cm medicine bag made of a single layer undershirt cloth, and the medicine can be separated by sewing two lines in the middle of the medicine bag to prevent the medicine powder from accumulation. In treatment, the medicine bag is fixed in a brassiere of a patient, and is changed every week, with half a month as one course of the treatment. Patients in a less severe state can be cured in 2-3 courses, while patients in a severe state can be cured in 5-6 courses.

The invention relates to a pure component traditional Chinese medicinal formulation for treating functional dyspepsia, which is prepared by taking Radix Bupleuri (Bupleurum chinense and / or Bupleurum scorzonerifolium), Paeonia lactiflora (Radix Paeoniae Alba), Cyperus rotundus, Atractylodes macrocephala, Melia toosendan fruit, Flos Inulae (Inula japonica and / or Inula britannica), Fructus Aurantii Immaturus (Citrus aurantium and / or Citrus sinensis) and Corydalis yanhusuo as a basic prescription, extracting a component A which uses volatile oil as a main ingredient, a component B which uses sesquiterpene lactone as main ingredient, a component C which uses alkaloid as a main ingredient, a component D which uses flavone as a main ingredient, a component E which uses saponin as a main ingredient and a component F which uses polysaccharide as a main ingredient from the basic prescription with a flash extraction technology, wherein the traditional Chinese medicinal formulation comprises the following components in parts by weight: 5-35 parts of the component A, 5-35 parts of the component B, 5-45 parts of component C, D 5-40 parts of the component D , 10-25 parts of the component E, and 5-40 parts of the component F. The traditional Chinese medicinal formulation is used for treating functional dyspepsia which belongs to liver-stomach disharmony in traditional Chinese medicine with symptoms of stomach duct swelling and pain, pain action or pain worse in case of worry, pain relief after belching and intestinal flatus from anus, chest distress, belching, inhibited defecation, thin and white tongue, and wiry pulse.

A pharmaceutical composition with an immunomodulating function is provided, including an extract of Bupleurum obtained by grinding the Bupleurum, adding the ground Bupleurum to a solvent and isolating the extract from the solvent, wherein the Bupleurum comprises Bupleurum krlovianum, Bupleurum longiradiatum, Bupleurum smithii, Bupleurum pusillum, Bupleurum longicaule, Bupleurum salicifolium, Bupleurum scorzonerifolium and Bupleurums with at least one of the nucleotide sequences selected from a group consisting of SEQ ID NOs. 1˜6 and a nucleotide sequence with no more than 1% of the nucleotide sequence divergences of SEQ ID NOs. 1˜6, or combinations thereof.

The invention relates to the field of medicines, discloses an application of radix bupleuri in preparation of medicines for preventing and treating ionizing radiation injuries, and discloses an application of a total extract of honewort or bupleurum scorzonerifolium in preparation of medicines for preventing and treating the ionizing radiation injuries. A radix bupleuri extract disclosed by the invention plays a radiation protection role in cellular level and animal living level, and plays a protective role under wide dosage ranges of lethal dosage, sub-lethal dosage and low irradiation dosage; and the radix bupleuri extract is stable in quality, low in cost, and wide in source, and can be applied to preparation of medicines for treatment of related injuries caused by ionizing radiation and disease treatment.