The invention discloses a laser cutting machine with an efficient and intelligent lifting exchanging table, and belongs to the technical field of special machining. The laser cutting machine comprisesa main bed body, a lifting table, a lower cutting box, an upper cutting box, a protective cover, an operation station, an electric control cabinet, a moving beam, a laser cutting head, a set of falling trolleys and a dust removal system. The main bed body is provided with a front deceleration sensor, a front stop sensor, a rear stop sensor, a rear deceleration sensor, an upper in-place sensor, anintermediate sensor, a lower in-place sensor, a transmission assembly, a driving assembly and a first guiding rail. According to the laser cutting machine, signal data of all the sensors need to be extracted firstly and received by a control system, the current position states of two material platforms are judged through the data, and then subsequent actions of the two material platforms are controlled, so that the material platforms reach the required working positions quickly and automatically; and in this way, the two material platforms can achieve one-key exchanging at any position, automatic material exchanging is achieved, and the working efficiency is improved.