The invention provides a detection method for survival prognosis of glioblastoma. The method is characterized in that the method comprises the following steps: the expression levels of specific expression genes CBX3, BARD1, EGFR, IFRD1, CTSS, STAT1, GUCY1A3 and MOBP in a glioblastoma tissue are detected, survival prognosis of a glioblastoma patient is predicted according to the expression level ofthe detected gene, and the survival time of the glioblastoma patient highly expressing CBX3, BARD1, EGFR, IFRD1, CTSS or / and STAT1 is short; the glioma patient with high expression of GUCY 1A3 or / andMOBP has a long survival time. The invention also provides a prognostic typing method for glioblastoma. The glioblastoma with high expression of CBX3, BARD1, EGFR, IFRD1, CTSS or / and STAT1 in glioblastoma tissues is / are short in prognostic survival time; and the high expression of the GUCY 1A3 or / and MOBP in the cytoma tissue is prognosis, and the survival time is long.