The invention relates to pretreatment equipment for pesticide residue detection. The device comprises a bottom plate, a top cover, a controller, a crushing mechanism, a water supply mechanism, a container, a shaking mechanism, two supporting plates and two placing mechanisms. The crushing mechanism comprises a reciprocating assembly, a reciprocating plate, a flat plate, a cutting ring, two directional assemblies, a plurality of blades and a plurality of first springs. The shaking mechanism comprises a plurality of shaking assemblies; and each shaking assembly comprises a vertical rod, a firstmotor, an eccentric wheel, a driving ring and a plurality of second springs. According to the pretreatment equipment for pesticide residue detection, a vegetable sample is cut into fragments through the crushing mechanism; juice in the vegetable fragments can be conveniently dissolved into distilled water to form an extracting solution; moreover, the shaking mechanism is used for shaking the container, so that juice in the vegetable fragments is fully dissolved in distilled water to form an extracting solution, an operator can conveniently detect the extracting solution through a pesticide residue rapid detection card, and thus the pesticide residue detection efficiency and precision are improved, and the practicability of the equipment is improved.