33results about How to "Reduce the likelihood of relapse" patented technology

Disclosed herein are methods of treating benign, pre-cancerous, or non-metastatic tumors using an anti-VEGF-specific antagonist. Also disclosed are methods of treating a subject at risk of developing benign, pre-cancerous, or non-metastatic tumors using an anti-VEGF-specific antagonist. Also disclosed are methods of treating or preventing recurrence of a tumor using an anti-VEGF-specific antagonist as well as use of VEGF-specific antagonists in neoadjuvant and adjuvant cancer therapy.

The invention relates to a source applicator for anal canal tumor radiotherapy, the source applicator comprises a cylindrical source applicator body of which the diameter is 3cm, wherein the front end of the source applicator body is a spherical arc, the front segment of the source applicator body is a right cylinder segment of which the length is 8.5cm, the right cylinder segment comprises the spherical arc at the front end, the rear segment of the source applicator body is bent in a manner of a 150-degree arc, the arc length of an introvert of an arc-shaped bent segment is 5cm, the source applicator body is internally and axially provided with three source applying tubes which are eccentrically arranged in a semicircle of the introvert side of the cross section of the source applicator body and distributed in a manner of a circular curve, and the distance between the center of each source applying tube and the outer wall of the introvert side of the source applicator body is 5.5cm; an arc between the circle center of the first source applying tube and the circle center of the second source applying tube is equal to an arc between the circle center of the second source applying tube and the circle center of the third source applying tube, and a central angle corresponding to the arc is 60 degrees. The source applicator has a good radiotherapy effect on nidus that part carcinoma of the anal canal spreads outside the anus edge, reduces the possibility of tumor recurrence and facilitates radical cure of the tumor.

The invention provides a CD19 and CD22 double-target chimeric antigen receptor and application thereof. The chimeric antigen receptor comprises an antigen binding structural domain, a transmembrane structural domain and a signal transduction structural domain; and the antigen binding structural domain comprises a light chain variable region of an anti-CD19 single-chain antibody, a heavy chain variable region of the anti-CD19 single-chain antibody, a light chain variable region of an anti-CD22 single-chain antibody and a heavy chain variable region of the anti-CD22 single-chain antibody. The anti-CD19 and anti-CD22 double-target chimeric antigen receptor disclosed by the invention has targeting activity on CD19 positive and/or CD22 positive cells; the T cells expressing the anti-CD19 and anti-CD22 double-target chimeric antigen receptor has a killing effect on tumor cells with low CD19 antigen expression quantity or no CD19 antigen expression quantity and tumor cells with low CD22 antigen expression quantity or no CD22 antigen expression quantity, so that the immune escape phenomenon is avoided, and the possibility of disease recurrence is reduced.

The invention discloses a self-locking bone-supporting anti-rotation bone distractor, and belongs to the field of medical equipment. The self-locking bone-supporting anti-rotation bone distractor canbe fixed at the top of an iliac crest by six or four anchorage nails, and an orthodontic force is directly transmitted to a palatal suture, thereby maximizing the bony effect without generating a tooth effect. Locking screws prevent rotation, so that the possibility of recurrence is reduced, and the stability of an arch is increased; a rotating rod can wrap complicated structures inside threaded tracks, so as to avoid food accumulation in gaps of these structures, and an oral cavity is easy to clean.

The invention discloses an orally taken Chinese medicine medicinal liquor used for treatment of bone injuries at early-middle stages. The liquor includes, by weight, 10-20 parts of woodlice, 5-15 parts of lumbricus, 7-17 parts of prepared spontaneous-combustion copper, 10-20 parts of cortex albiziae, 10-20 parts of angelica sinensis, 7-17 parts of rhizoma corydalis, 7-17 parts of radix curcumae, 7-17 parts of ligusticum wallichii, 7-17 parts of radix gentianae macrophyllae, 5-15 parts of rhizoma sinomeni cauliset, 5-15 parts of radix clematidis, 7-17 parts of radix angelicae pubescentis, 7-17parts of notopterygium incisum, 7-17 parts of pawpaws, 2-8 parts of radix aconiti preparata, 2-8 parts of prepared kusnezoff monkshood roots, 10-20 parts of barks of himalayan coralbean, 10-20 parts of cortex acanthopanacis, 10-20 parts of caulis spatholobi, 10-20 parts of radix dipsaci, 10-25 parts of loranthus parasiticus, 10-20 parts of prepared myrrh and 10-20 parts of zaocys dhumnade. All Chinese medicine components cooperate with one another to regulate the body of a patient as a whole, the patient can better absorb the medicine components for treatment of the injuries at the early-middle stages, the liquor also plays an auxiliary effect in the later recovery process of the patient, the recovery cycle of the patient is shortened, and the possibility of disease recurrence is reduced.

The invention belongs to the technical field of medical assistance, and particularly relates to a medical assistance system based on augmented reality and finite element analysis and a use method, the medical assistance system comprises medical image data, a cloud database, a model extraction optimization part, an AR display part and a biomechanical analysis part; the AR display part comprises a first receiving module, an adjusting module, an output module and a display device; the biomechanical analysis part comprises a second receiving module, a selection module, a filling module, an adjusting module and a calculation and analysis module; two technologies of finite element analysis and augmented reality are applied to medical treatment, and the situation that a doctor can only check the illness condition through CT or nuclear magnetic resonance two-dimensional images traditionally is changed; and through augmented reality formed by the AR display part and biological finite element analysis formed by the biomechanical analysis part, the problem of high difficulty in preoperative planning and postoperative specifying of exclusive rehabilitation measures of a patient during existing medical treatment is effectively solved or improved.