The invention provides a plaster for treating cervical spondylosis, lumbar spondylosis and various arthritis. The plaster is characterized by comprising the following medicinal materials by weight: 120g of semen brassicae, 120g of euphorbia kansui, 120g of earthworm meat, 150g of radix clematidis, 150g of garden balsam, 150g of phryma leptostachya, 18g of asarum, 240g of smoked plum pulp, 60g of crinis ustus, 60g of scorpion, 70g of divaricate saposhnikovia root, 20g of purpurea halitium, 120g of rhizoma drynariae, 200g of kudzuvine root, 60g of raw radix aconiti agrestis, 25g of Chinese angelica, 50g of dragon blood, 100g of frankincense, 50g of pangolin, 18g of dried tangerine peel, 15g of fructus amomi, 20g of costustoot, 2500g of sesame oil, 1300g of yellow lead and 30g of azone. The preparation process comprises the following steps: (1) weighing the medicinal materials by weight ratio except the sesame oil, the yellow lead and the azone, baking, grinding into fine powder, screening through a 100-mesh screen, and sealing the medicinal powder for later use; (2) boiling the 2500g of sesame oil in an iron pot with slow fire, slowly and uniformly spreading the 1300g of yellow lead into the sesame oil, quickly stirring by a willow stick along one direction constantly to homogenize the mixture; shutting down the fire when a small amount of dipped mixture drops into cold water and cannot be dispersed, cooling to 60-70 DEG C, adding the medicinal powder and 30g of azone into the mixture, uniformly stirring, and apportioning the hot medicinal materials on prepared non-woven fabrics or animal skins to obtain the plaster for treating rheumatic pains.