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441results about How to "Quantitative precision" patented technology
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Interactive orthodontic care system based on intra-oral scanning of teeth
InactiveUS20050043837A1Quantitative precisionHighly reliable mannerImpression capsTherapiesInteractive softwareOff the shelf
Interactive, computer based orthodontist treatment planning, appliance design and appliance manufacturing is described. A scanner is described which acquires images of the dentition which are converted to three-dimensional frames of data. The data from the several frames are registered to each other to provide a complete three-dimensional virtual model of the dentition. Individual tooth objects are obtained from the virtual model. A computer-interactive software program provides for treatment planning, diagnosis and appliance from the virtual tooth models. A desired occlusion for the patient is obtained from the treatment planning software. The virtual model of the desired occlusion and the virtual model of the original dentition provide a base of information for custom manufacture of an orthodontic appliance. A variety of possible appliance and appliance manufacturing systems are contemplated, including customized archwires and customized devices for placement of off-the shelf brackets on the archwires, and removable orthodontic appliances.
Owner:ORAMETRIX
Non-contact optical system, computer-accessible medium and method for measurement at least one mechanical property of tissue using coherent speckle technique(s)
ActiveUS9351642B2Good curative effectEasy to measureDiagnostics using lightCatheterAnatomical structuresMechanical property
Exemplary embodiments of apparatus and method for determining at least one material property of an anatomical structure can be provided. According to one exemplary embodiment, it is possible to apply at least one first coherent radiation to at least one portion of the anatomical structure, and receive at least one second coherent radiation from such portion(s). The first and second coherent radiations can be associated with one another. In addition, it is possible to determine the material property based on the second coherent radiation(s). Such determination can be performed without (i) any portion of an apparatus performing the procedure causing an induction of at least one mechanical deformation on or in the anatomical structure, and / or (ii) any mechanical deformation on or in the anatomical structure.
Owner:THE GENERAL HOSPITAL CORP
Interactive orthodontic care system based on intra-oral scanning of teeth
InactiveUS7013191B2Quantitative precisionHighly reliable mannerImpression capsTherapiesInteractive softwareOff the shelf
Owner:ORAMETRIX
Virtual bracket placement and evaluation
A method and apparatus for facilitating placement and evaluation of virtual appliances on virtual teeth of an orthodontic patient are described. Positioning references comprising bracket height, occlusal plane, or any arbitrary plane are provided to facilitate desired placement of virtual appliances on virtual teeth model. The process can be applied with any dentition state of a patient such as malocclusion, target state from treatment, or intermediate monitored state during the course of a treatment. An unified workstation for treatment planning provides the computer software tools for verification, simulation and evaluation of the virtual appliance placement. The process enables proper planning of treatment for an orthodontic patient suffering from malocclusion involving bonding of virtual brackets to the surface of the patient's virtual teeth with archwires placed in the slots of the brackets, so as to realize the desired results from the treatment in the most desired manner.
Owner:ORAMETRIX
Autofluorescence imaging system for endoscopy
InactiveUS20110213252A1Improve featuresQuantitative precisionSurgeryEndoscopesColor imageUltraviolet lights
A system and method for imaging tissue autofluorescence through a video endoscope is described, comprising a light source capable of providing both ultraviolet light capable of inducing tissue autofluorescence and visible light which induces little or no autofluorescence, an optical system to deliver both wavelength bands to the tissue with the same apparent spatial and angular intensity distribution, a means for digitally acquiring the resulting, visible fluorescence and visible reflectance images using a single imaging detector at the distal tip of the endoscope and a means for digitally processing said images to generate a final, false-color image for display which indicates regions of tissue dysplasia. This system can either be added on to an existing video endoscope or integrated into its structure. The combined system can be electronically switched between normal white light imaging and fluorescence imaging.
Owner:HOYA CORP
Handheld Apparatus For Quantifying Component Features
ActiveUS20140021259A1Accurate distance measurementQuantitative precisionImage enhancementImage analysisHand held devicesField of view
A handheld device and method using the device, the device comprising a sensor receiving light from within a field of view (FOV) to generate a plurality of consecutive images of the FOV, a structured light source that is controllable to generate a plurality of light patterns, the source arranged to project at least one light patterns into the FOV where at least a portion of a pattern reflects from an object and is captured by the sensor and a processor to receive images, the processor programmed to control the source to project a pattern into the FOV, locate the pattern in at least one of the generated images, locate discontinuities in the pattern and use the discontinuities to measure at least one dimension.
Owner:COGNEX CORP
Detecting Cell Surface Markers
InactiveUS20110111435A1Quantitative precisionBiological material analysisBiological testingSurface markerCell surface staining
In one aspect, the present invention provides a method for detecting an expression level of a cell surface marker in a sample, comprising staining the sample with a reagent that labels the cell surface marker; obtaining an image of the stained sample; and determining a value for continuity of cell surface staining in the image, wherein the value is indicative of the expression level.
Owner:LEICA BIOSYST IMAGING
Canola cultivar NQC02CNX21
ActiveUS20060225146A1DegreeImprove nutritional qualityOther foreign material introduction processesFermentationBrassicaGenetic Materials
A canola cultivar designated NQC02CNX21 is disclosed. The invention relates to the seeds of canola cultivar NQC02CNX21, to the plants of canola NQC02CNX21, to plant parts of canola cultivar NQC02CNX21 and to methods for producing a canola plant produced by crossing canola cultivar NQC02CNX21 with itself or with another canola line. The invention also relates to methods for producing a canola plant containing in its genetic material one or more transgenes and to the transgenic canola plants and plant parts produced by those methods. This invention also relates to canola cultivars or breeding cultivars and plant parts derived from canola cultivar NQC02CNX21, to methods for producing other canola cultivars, lines or plant parts derived from canola cultivar NQC02CNX21 and to the canola plants, varieties, and their parts derived from use of those methods. The invention further relates to hybrid canola seeds, plants and plant parts produced by crossing the canola cultivar NQC02CNX21 with another canola cultivar.
Owner:CORTEVA AGRISCIENCE LLC
Movement disorder monitoring and symptom quantification system and method
InactiveUS20140257141A1Correct symptomsMaximizes subject safetyPerson identificationSensorsDiseaseKinetic information
The present invention relates to a movement disorder monitor with high sensitivity, and a method of measuring the severity of a subject's movement disorder. The present invention additionally relates to a drug delivery system for dosing a subject in response to the increased severity of a subject's symptoms. The present invention provides for a system and method, which can accurately and repeatably quantify symptoms of movements disorders, accurately quantifies symptoms utilizing both kinetic information and / or electromyography (EMU) data, that can be worn continuously to provide continuous information to be analyzed as needed by the clinician, that can provide analysis in real-time, that allows for home monitoring of symptoms in subject's with these movement disorders to capture the complex fluctuation patterns of the disease over the course of days, weeks or months, that maximizes subject safety, and that provides substantially real-time remote access to data by the clinician or physician.
Owner:GREAT LAKES NEUROTECH
Canola cultivar NQC02CNX12
InactiveUS20060075516A1Improve nutritional qualityQuantitative precisionOther foreign material introduction processesFermentationRapeseedCultivar
A canola cultivar designated NQC02CNX12, plants and seeds of the NQC02CNX12 canola cultivar, methods for producing a canola plant produced by crossing the NQC02CNX12 cultivar with itself or with another canola plant, and hybrid canola seeds and plants produced by crossing the NQC02CNX12 cultivar with another canola cultivar or plant are provided.
Owner:DOW AGROSCIENCES LLC
Methods and compositions for assessing acute rejection
InactiveUS20090022730A1Accurate detectionMinimize and personalize immunosuppressionMicrobiological testing/measurementAntibody ingredientsTransplant rejectionGene
The invention relates to the analysis and identification of genes that are up-regulated simultaneously in transplant rejection. This simultaneous up-regulation of genes provides a molecular signature to accurately detect transplant rejection.
Owner:NOVARTIS AG +1
Canola cultivar NQC02CNX25
ActiveUS20060075517A1DegreeImprove nutritional qualityOther foreign material introduction processesFermentationCultivarBrassica oleracea
A canola cultivar, designated NQC02CNX25, plants and seeds of the NQC02CNX25 canola cultivar, methods for producing a canola plant produced by crossing the NQC02CNX25 cultivar with itself or with another canola plant, and hybrid canola seeds and plants produced by crossing the NQC02CNX25 cultivar with another canola cultivar or plant are provided.
Owner:CORTEVA AGRISCIENCE LLC
High fidelity detection of nucleic acid differences by ligase detection reaction
InactiveUS7244831B2Improve fidelityAlteration in rateSugar derivativesMicrobiological testing/measurementBiologyOligonucleotide
Ligase detection reaction is utilized to distinguish minority template in the presence of an excess of normal template with a thermostable ligase. This process can be carried out with a mutant ligase, thermostable ligase, or a modified oligonucleotide probe. This procedure is particularly useful for the detection of cancer-associated mutations. It has the advantage of providing a quantitative measure of the amount or ratio of minority template.
Owner:CORNELL RES FOUNDATION INC +1
Closed-system multi-stage nucleic acid amplification reactions
ActiveUS20060177844A1Avoid adsorptionFacilitate reagent movementHeating or cooling apparatusMicrobiological testing/measurementReactive systemSystems approaches
The invention is directed to systems, methods, and apparatus for carrying out multi-stage amplification reactions, especially under fluidly closed conditions. In one aspect, methods of the invention are carried out in a fluidly closed reaction system that permits the isolation of a portion of a first (or prior) reaction mixture and its use as a sample or specimen in a second (or subsequent) reaction mixture, thereby substantially avoiding interfering effects that first reaction components may have in the second reaction if both reaction mixtures were simply combined together. In this aspect, systems, methods, and apparatus of the invention may be used with any amplification reaction that permits multiple stages of amplification based on the use of nested primers.
Owner:CEPHEID INC
Closed-system multi-stage nucleic acid amplification reactions
ActiveUS8133703B2Quantitative precisionHigh sensitivityHeating or cooling apparatusMicrobiological testing/measurementReactive systemClosed system
The invention is directed to systems, methods, and apparatus for carrying out multi-stage amplification reactions, especially under fluidly closed conditions. In one aspect, methods of the invention are carried out in a fluidly closed reaction system that permits the isolation of a portion of a first (or prior) reaction mixture and its use as a sample or specimen in a second (or subsequent) reaction mixture, thereby substantially avoiding interfering effects that first reaction components may have in the second reaction if both reaction mixtures were simply combined together. In this aspect, systems, methods, and apparatus of the invention may be used with any amplification reaction that permits multiple stages of amplification based on the use of nested primers.
Owner:CEPHEID INC
Canola cultivar NQC02CNX13
InactiveUS20060225159A1DegreeImprove nutritional qualityOther foreign material introduction processesFermentationGenetic MaterialsRapeseed
A canola cultivar designated NQC02CNX13 is disclosed. The invention relates to the seeds of canola cultivar NQC02CNX13, to the plants of canola NQC02CNX13, to plant parts of canola cultivar NQC02CNX13 and to methods for producing a canola plant produced by crossing canola cultivar NQC02CNX13 with itself or with another canola line. The invention also relates to methods for producing a canola plant containing in its genetic material one or more transgenes and to the transgenic canola plants and plant parts produced by those methods. This invention also relates to canola cultivars or breeding cultivars and plant parts derived from canola cultivar NQC02CNX13, to methods for producing other canola cultivars, lines or plant parts derived from canola cultivar NQC02CNX13 and to the canola plants, varieties, and their parts derived from use of those methods. The invention further relates to hybrid canola seeds, plants and plant parts produced by crossing the canola cultivar NQC02CNX13 with another canola cultivar.
Owner:DOW AGROSCIENCES LLC
System and method for whole body landmark detection, segmentation and change quantification in digital images
ActiveUS7876938B2Quantitative precisionGood segmentation resultImage enhancementImage analysisAnatomical landmarkImage resolution
Owner:SIEMENS HEALTHCARE GMBH
Canola cultivar NQC02CNX25
ActiveUS7348473B2Improve nutritional qualityQuantitative precisionOther foreign material introduction processesTissue cultureCultivarBrassica oleracea
Owner:CORTEVA AGRISCIENCE LLC
Canola cultivar NQC02CNX12
InactiveUS7355100B2Improve nutritional qualityQuantitative precisionOther foreign material introduction processesTissue cultureCultivarBrassica oleracea
A canola cultivar designated NQC02CNX12, plants and seeds of the NQC02CNX12 canola cultivar, methods for producing a canola plant produced by crossing the NQC02CNX12 cultivar with itself or with another canola plant, and hybrid canola seeds and plants produced by crossing the NQC02CNX12 cultivar with another canola cultivar or plant are provided.
Owner:DOW AGROSCIENCES LLC
Method and apparatus for non-invasive prediction of intrinsic positive end-expiratory pressure (PEEPi) in patients receiving ventilator support
ActiveUS20050284476A1Accurate detectionQuantitative precisionRespiratorsOperating means/releasing devices for valvesAutonomous breathingAir volume
The present invention describes a method and apparatus for non-invasive prediction of the “intrinsic positive end-expiratory pressure” (PEEPi) which is secondary to a trapping of gas, over and above that which is normal in the lungs; the presence of PEEPi imposes an additional workload upon the spontaneously breathing patient. Several indicators or markers are presented to detect and quantify PEEPi non-invasively The markers may include an expiratory air flow versus expiratory air volume trajectory, an expiratory carbon dioxide flow versus expiratory air volume trajectory, an expiratory carbon dioxide volume to expiratory air volume ratio, an expiratory air flow at onset of inhalation, a model of an expiratory waveform, a peak to mid-exhalation airflow ratio, duration of reduced exhaled airflow, and a Capnograph waveform shape.
Owner:CONVERGENT ENG
Apparatus and method for using optical mouse engine to determine speed, direction, position of scanned device and to obtain quantitative or qualitative data from same
ActiveUS20050095697A1High speed data read rateHigh speed sensitivityBioreactor/fermenter combinationsBiological substance pretreatmentsMicrocontrollerHigh rate
A test strip reader is provided with an optical mouse integrated circuit sensor that reads the test line, reference line and control line of a lateral flow assay strip by light absorption and determines the position of the test strip beneath the image on the integrated circuit board using digital signal processing algorithms. The digital signal processing algorithms process the imaged surface at a very high rate (e.g., 1500 frames per second) to determine the direction and speed of movement of the lateral strip with respect to the reader optics and image capture components. The sensor outputs this position information in a quadrature pattern format. A microcontroller uses the known position of the strip with respect to the reader to calculate the optical absorption of each colored reagent line, and the diagnostic significance (i.e., either qualitative or quantitative) of the test strip.
Owner:BECTON DICKINSON & CO
System and method for blood vessel stenosis visualization and quantification using spectral ct analysis
ActiveUS20120076377A1For accurate visualizationQuantitative precisionMaterial analysis using wave/particle radiationRadiation/particle handlingX-rayData acquisition
A system and method for dual energy CT spectral imaging that provides for accurate blood vessel stenosis visualization and quantification is disclosed. The CT system includes an x-ray source configured to project x-rays toward a region-of-interest of a patient that includes a blood vessel in a stenosed condition and having a plaque material therein. The CT system also includes an x-ray detector to receive x-rays emitted by the x-ray source and attenuated by the region-of-interest, a data acquisition system (DAS) operably connected to the x-ray detector, and a computer programmed to obtain a first set of CT image data for the region-of-interest at a first chromatic energy level, obtain a second set of CT image data for the region-of-interest at a second chromatic energy level that is higher than the first chromatic energy level, and identify plaque material in the region-of-interest by analyzing the second set of CT image data.
Owner:GENERAL ELECTRIC CO
High dynamic range mass spectrometer
InactiveUS6969847B2Reduce the numberImprove dynamic rangeThermometer detailsTime-of-flight spectrometersUltrasound attenuationA d converter
A mass spectrometer comprises an ion source which produces an ion beam from a substance to be analysed and a detector to detect a quantity of ions incident thereon. The detector includes two elements (16, 18) each of which detect a part of the quantity of ions and an attenuation device attenuates the quantity of ions reaching one of the detector elements. At least one of the detector elements (16, 18) is connected to a time to digital converter (TDC) to allow counting of the ions and at least one of the detector elements is connected in parallel to both a time to digital converter (TDC) and an analogue to digital converter (ADC).
Owner:THERMO FINNIGAN
Virtual bracket placement and evaluation
InactiveUS7296996B2Improve accuracy and consistencyEvaluate effectivenessBracketsImpression capsDental malocclusionProper treatment
A method and apparatus for facilitating placement and evaluation of virtual appliances on virtual teeth of an orthodontic patient are described. Positioning references comprising bracket height, occlusal plane, or any arbitrary plane are provided to facilitate desired placement of virtual appliances on virtual teeth model. The process can be applied with any dentition state of a patient such as malocclusion, target state from treatment, or intermediate monitored state during the course of a treatment. An unified workstation for treatment planning provides the computer software tools for verification, simulation and evaluation of the virtual appliance placement. The process enables proper planning of treatment for an orthodontic patient suffering from malocclusion involving bonding of virtual brackets to the surface of the patient's virtual teeth with archwires placed in the slots of the brackets, so as to realize the desired results from the treatment in the most desired manner.
Owner:ORAMETRIX
Measurement of protective genes in allograft rejection
InactiveUS6900015B2Quantitative precisionAccurately allograft rejectionMicrobiological testing/measurementDisease diagnosisCytotoxicityAllograft rejection
The invention relates to methods of evaluating transplant rejection in a host comprising determining a heightened magnitude of gene expression of genes in rejection-associated gene clusters. The disclosed gene clusters include genes that are substantially co-expressed with cytotoxic lymphocyte pro-apoptotic genes, cytoprotective genes and several other cytokine and immune cell genes.
Owner:BETH ISRAEL DEACONESS MEDICAL CENT INC +1
Canola Plants with High Oleic and Low Linolenic
ActiveUS20090093367A1DegreeQuantitative precisionBiocideAnimal repellantsHigh oleic acidOleic Acid Triglyceride
Canola plants with high oleic acid and low linolenic acid content are disclosed. In addition, the canola plants of the invention are resistant to imidazolinone herbicides and are resistant to blackleg. The canola plants of the invention also have low total glucosinolate content. There is also provided a method for controlling weeds in a field of canola plants wherein the canola plants are herbicide resistant.
Owner:CORTEVA AGRISCIENCE LLC
Method of quantifying a subject's wake or sleep state and system for measuring
InactiveUS7860561B1Accurate and high resolution characterizationAccurate representationElectroencephalographySensorsSleep stateImage resolution
The present invention relates to a method of quantifying a subject's wake or sleep state, and more particularly to a higher resolution method of determining when a subject is awake or asleep. The present invention additionally relates more specific applications of this method, and a system for making these quantitative measurements. There are numerous embodiments of the present invention, which are envisioned, with a few of those listed below. The present invention relates to a method of analyzing a subject, and preferably a human subject to determine quantitatively when the subject is awake and when the subject is sleeping. The present invention has application for use with alertness devices, for use to better analyze sleeping disorders, anesthesia monitors, psychiatric and hypnosis medication monitoring, and for looking at the effect of various other therapies.
Owner:CLEVELAND MEDICAL DEVICES
Injection molding method and apparatus
InactiveUS7906048B2Enhanced performance characteristicReduce pressure applyAuxillary shaping apparatusFood shapingSource materialInjection molding process
A thermoplastic injection molding system and method of use is described for molding parts from heated plastics and other organic resins. The machine uses heat sources located along the barrel to heat the source material while an auger screw transports the source material in the barrel. This transport step does not shear the source material, nor does it use friction to produce the heat necessary to melt the source material. The material becomes substantially liquid or melted during the heating process, and the melted material is forced, by the auger screw, into a chamber whereupon a plunger, situated concentrically with the auger screw, injects the material from the chamber into a mold. Sensors located along the barrel and in the chamber ensure consistency between mold cycles. The controller dynamically adjusts the injection molding process to achieve more consistent and reliable molded parts.
Owner:KOALESCE
Apparatus, system and methods for measuring a blood pressure gradient
ActiveUS20140249386A1Minimal disruptionMinimal and negligible disruptionMechanical/radiation/invasive therapiesVolume/mass flow measurementElectrical connectionOptical coupler
An apparatus (100), control system (150) and methods are provided for directly measuring a pressure gradient, i.e. by real-time pressure measurements, with particular application for in situ measurement of transvalvular blood pressure gradients for the aortic valve and other heart valves, using minimally-invasive techniques. The apparatus takes the form of a multi-sensor assembly, e.g. enclosed within a micro-catheter or a steerable guidewire, and comprises a plurality of optical pressure sensors (10) is arranged along a length of the distal end portion (101), for measuring pressure simultaneously at each sensor location. For example, four MOMS optical pressure sensors (10), and optionally, a flow sensor (20), are incorporated into a distal end portion (101) having a diameter of 0.89 mm or less, and preferably 0.46 mm or less. Beneficially, all sensors are optically coupled, via respective optical fibers (11), to an optical coupler (112) at the proximal end of the multi-sensor apparatus, without requiring electrical connections.
Owner:HEMOCATH LTD
Hand-held wireless platform and optics for measurement of dna, rna, micrornas, and other markers of pathogens, genetic diseases, and cancer
InactiveUS20140211204A1Fast fluorescence detectionDetectable yieldMicrobiological testing/measurementLuminescent dosimetersDiseaseHand held
The present invention provides compositions for making and methods of using a hand-held nucleic acid amplification device, comprising a disposable biochip with a series of sample wells, each sample well having a novel optical arrangement that includes a light-emitting diode (LED) and a single light capturing element (e.g. a photodiode) for quickly measuring light emissions from biological samples such as nucleic acid amplification reactions. Such a device can utilize isothermal amplification for obtaining detectable yields of amplified nucleic acid product in short time periods, for example, within seconds.
Owner:BOARD OF TRUSTEES OPERATING MICHIGAN STATE UNIV
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