The invention provides an ecological protection slope based on a multi-protection device for a water conservancy project. The ecological protection slope comprises a to-be-protected soil slope, a nameboard, a fixing rod, a reflecting plate, a fixing plate, an upper protection plate, a locking bolt, a main protection fixing cone structure, a slope protection upper protection guardrail structure, afirst-stage V-shaped connecting plate, a second-stage V-shaped connecting plate, an ecological protection planting turf structure, a connection bolt, a side protection and maintenance guardrail structure, a square head bolt and an auxiliary slope fixing cone; and the name board is arranged at the upper end of the fixing rod in a screwed mode. Guardrail bodies, ejector rods, an end protective handrail and end rods are arranged, so that the safety protection effect is improved; connecting belts, a protective net and linking plates are arranged, so that the use safety of the protective slope isimproved, and meanwhile, the risk that a maintainer falls into the slope bottom carelessly can be avoided; and maintaining guardrails, connecting plates and a side protecting connecting plate are arranged, so that nursing personnel facilitates nursing of the protective slope and can be used for holding the maintaining guardrails.