44results about How to "Minimize destruction" patented technology

The present invention relates to a method and a device for alleviating and / or preventing conditions relating to damaged joints involving articulating surfaces. In a first aspect the present invention relates to a prosthetic device for insertion into a joint cavity of a joint of a vertebrate, such as a human, said device consisting of a biocompatible material comprising at least a first polymeric component and a second polymeric component, wherein the chain length of the first polymeric component is longer than the chain length of the second polymeric component, the polymeric components in particular being polyethylene, polypropylene and / or polyvinylpyrrolidone. A further aspect of invention relates to a method for introducing the prosthetic device into a joint, such as a method comprising locking the device to an intro-articular component, thereby fixing or retaining the device in the joint cavity in a manner which is substantially non-invasive with respect to cartilage and bone natively present in the joint cavity. Also the invention relates to an instrument for inserting a prosthetic device according to the invention, comprising means for deforming the prosthetic device into a reduced volume or a slender shape and means for grasping the intra-articular component to which the device is capable of interlocking.

A method for creating a tissue effect provides a substrate with a releasable coating. At least a portion of the releasable coating is released on a selected skin epidermis surface to create a marked skin epidermis surface. The marked skin epidermis surface is used to provide a guide for delivery of energy from an energy source to a tissue site through at least a portion of the marked skin epidermis surface.

An arrangement for performing an animal-related action on an animal includes a position determining component having a detector and a processing unit for determining the position of an animal part to be subjected to the animal-related action, and a performance component such as an animal handling unit or milking robot for performing the animal-related action. The position determining component is located at a first location including a station for housing an animal and the performance component is located at a second location including a station for housing an animal at a distance from the first location. A signal line is provided for transferring the coordinates of the position determined at the first location to the performance component at the second location in order to enable the performance of the action with regard to the animal part.

A two-dimensional image projection device using array of micromirror array lenses and a random scanning technique is invented. Using the random scanning technique, the light efficiency is nearly doubled than that of the prior art. The invention makes a brighter and less power consuming display device possible. Because each micromirror array lens of array of micromirror array lenses can scan whole image plane, a fast self diagnosis and correction technique can be introduced in displaying device. The Self diagnosis and correction technique makes display device to maintain image quality even a few tens percent of micromirrors do not work properly. Owing to the scanning characteristics of micromirror array lens, the image projection device can express the same number of pixels image with less number of micromirrors than the prior art. This also enables small sized two-dimensional image projector, which can be incorporated in portable electronic equipments.

Apparatus for forming articles in a thermoplastic sheet, severing the articles in the sheet, and stacking the articles in a stacking receiver. The apparatus includes upper and lower molds moveable between closed positions in which the molds engage opposite sides of the sheet to differentially pressure form a part in the thermoplastic sheet. The molds in which the article is formed are moved toward each from the closed positions to article trim positions to sever the article from the sheet. The lower mold is then moved linearly away from the sheet in a vertical direction and then transversely moved in a second linear transverse path of travel to a remote discharge location. Apparatus is provided for reorienting the mold between its orientation in the first linear path of travel and its orientation in the second path of travel.

An air venting apparatus for a milk bottle having a soft teat for a baby to suck, a bottle for containing milk, and a fixing frame for fixing the soft teat to the bottle without leakage. In the air venting apparatus, an upper plate is disposed between the top of a body of the bottle and the base of the teat and has at least one air inlet groove for guiding external air into the bottle body. A lower plate is combined with the upper plate and has at least one thorough hole and an air control valve to control the amount of the introduced air and discharges a gas generated from high-temperature milk outside the bottle body. An annular connection member is combined with the lower plate and provides the amount-controlled air into the bottle body.

The present invention relates to a positive electrode active material for a lithium secondary battery, a method for preparing the same and a lithium secondary battery including the same, the positive electrode active material includes a core including a first lithium complex metal oxide, and a shell located surrounding the core and including a second lithium complex metal oxide, and further includes a buffer layer located between the core and the shell, wherein the buffer layer includes a pore, and a three-dimensional network structure of a third lithium complex metal oxide which is connecting the core and the shell, and accordingly, minimizing destruction of the active material caused by a rolling process during the electrode preparation, and maximizing reactivity with an electrolyte liquid.

A continuous track with replaceable components permits a light weight tracked vehicle to benefit from the cost savings associated with repairable tracks. Each repairable track includes two parallel continuous belts, each belt includes embedded plates to reinforce the belts and distribute the load applied by the vehicle drive train and the load applied by the shoe to the belts. Each shoe assembly engages the parallel belts and includes a track guide, a shoe plate and a shoe. The number, separation and orientation of the shoe assemblies are preset for a set of parallel belts, however shoe assemblies and the elements of the shoe assemblies may be used for many different belt sets. Any suitable fasteners may be used to secure each shoe assembly to the belts.

A coagulation system for the coagulation of organic tissue includes a laser configured to emit a working beam; an interrupter configured to at least partially interrupt the working beam; a controller configured to activate the interrupter; and a detector configured to detect a signal corresponding to a degree of coagulation or alteration of the tissue and to transmit a detection of the signal to the controller, the detector including a dimension meter.

Disclosed is a T cell receptor (TCR) having antigenic specificity for an HLA-A2-restricted epitope of human papillomavirus (HPV) 16 E6, E629-38. Related polypeptides and proteins, as well as related nucleic acids, recombinant expression vectors, host cells, and populations of cells are also provided. Antibodies, or an antigen binding portion thereof, and pharmaceutical compositions relating to the TCRs of the invention are also provided. Also disclosed are methods of detecting the presence of a condition in a mammal and methods of treating or preventing a condition in a mammal, wherein the condition is cancer, HPV 16 infection, or HPV-positive premalignancy.

The invention is an improved cementitious mixture used to form structural components that are strong, lightweight, heat and fire resistant, and very economical to produce. The material includes a mixture of cement, water, ribbon-like virgin polyethylene strips and aggregate materials. The aggregate preferably includes recycled industrial waste products. Examples of these industrial wastes include shredded tires, wood by-products, waste coal combustion by-products, recycled waste gypsum products, recycled industrial foundry sand, and waste foam products such a Styrofoam. This new cementitious material is strong and lightweight. It has a lower thermal conductivity than conventional concrete and therefore improved insulative properties. The use of industrial recyclables not only enhances the performance characteristics of the components made from this material but aids in maintaining the environment by providing a practical use for industrial waste.

Access to the XAUI lanes of a 10 Gigabit Ethernet device is provided when needed for testing of the XAUI electrical interface. Access is provided by extending the XAUI interface contained in a XENPAK interface connector. An embodiment of the present invention uses an extension of the XENPAK connector to generate and receive XAUI signals thus making it possible for any device with a XENPAK connector to become a XUAI tester with minimal components between the test equipment and the device under test. The reduction of components (only an AC-Coupling capacitor resides between the XENPAK connector and the SMA connector) results in significant reduction in insertion loss and signal degradation. Also, the availability of any device with a XENPAK interface as a XAUI tester eliminates any requirement for specialized test equipments. The XAUI Extender card fits in the slot in the test equipment that would normally house the XENPAK module. Thus, no special connector is required to configure a device as a test equipment of the present invention.

A two-dimensional image projection device using array of micromirror array lenses and a random scanning technique is invented. Using the random scanning technique, the light efficiency is nearly doubled than that of the prior art. The invention makes a brighter and less power consuming display device possible. Because each micromirror array lens of array of micromirror array lenses can scan whole image plane, a fast self diagnosis and correction technique can be introduced in displaying device. The Self diagnosis and correction technique makes display device to maintain image quality even a few tens percent of micromirrors do not work properly. Owing to the scanning characteristics of micromirror array lens, the image projection device can express the same number of pixels image with less number of micromirrors than the prior art. This also enables small sized two-dimensional image projector, which can be incorporated in portable electronic equipments.

A method of integration of concentration-dehydration and aerobic air-drying of sewage sludge comprises the following steps: (a) conditioning by an organic agent (3); (b) gravitationally concentrating (5) the residual sludge conditioned by the organic agent; (c) conditioning by inorganic agents (7); (d) mechanically dehydrating (8); (e) crushing and dispersing (10); and (t) aerobically air-drying (11). The method has the following advantages: (i) to improve the sedimentation performance of the residual sludge, thus improving the concentration efficiency of sludge, reducing the concentrating time and reducing the volume of the concentrating pool; (ii) to reduce the volume of the dehydrated sludge correspondingly, thus reducing the subsequent heat treatment load; (iii) to have low energy consumption for drying; (iv) the sludge granules moving at low speed during the drying process, thus being produced stably and securely without powder; (v) the dried exhaust air can reach environmental-friendly standard discharge after being washed by water; (vi) the output sludge granules are not compact, which is good for reclamation.

A method is disclosed for making a pharmaceutical composition for pulmonary administration, the method comprising a step in which an inhalable pharmaceutically active material is acoustically blended in a resonant acoustic blender. The invention also relates to compositions for inhalation prepared by the method.

Disclosed is a T cell receptor (TCR) having antigenic specificity for an HLA-A2-restricted epitope of human papillomavirus (HPV) 16 E6, E629-38. Related polypeptides and proteins, as well as related nucleic acids, recombinant expression vectors, host cells, and populations of cells are also provided. Antibodies, or an antigen binding portion thereof, and pharmaceutical compositions relating to the TCRs of the invention are also provided. Also disclosed are methods of detecting the presence of a condition in a mammal and methods of treating or preventing a condition in a mammal, wherein the condition is cancer, HPV 16 infection, or HPV-positive premalignancy.

Provided is an anticancer prodrug sensitive to a target protease. The anticancer prodrug includes an anticancer drug, peptide that is specifically decomposed by the target protease excessively secreted by cancer cells, and a polymer that is specifically accumulated at a target cancer site. When the inactive anticancer prodrug is administered, the anticancer prodrug is accumulated at the target caner site and then the peptide is decomposed by irradiation of radioactive rays, thereby releasing an active anticancer drug at the target caner site. Accordingly, destruction of normal cells can be minimized and a high anticancer therapeutic effect can be obtained by using a small amount of the anticancer drug administered and a small amount of radioactive rays irradiated.

A dedicated device for detection of vascular shunts can include a first chamber, a second chamber, and a third chamber. The first chamber can be configured to hold liquid, the second chamber to hold gas, and the third chamber can be in communication with the first and second chambers. The third chamber can include small-scale geometric features configured to produce gas bubbles as liquid from the first chamber and gas from the second chamber simultaneously flow into the third chamber. The device can also include a device opening in communication with the third chamber such that a mixture of liquid and gas bubbles can flow out of the device opening. The device can also include a plunger configured to force the liquid and the gas simultaneously from the first and second chambers, through the third chamber to mix with each other and produce bubbles, and further through the device opening.

The present invention is directed to a system and method for pasteurizing milk and colostrum for feeding to calves. The system includes a vat for storing milk or colostrum, a circulation pump and piping system, a heat exchanger for adjusting and / or maintaining milk temperature, and an ultraviolet light pasteurizing unit (“UV reactor”) that treats the milk without damaging important immunoglobulins.

A control method is used with a control system to control a screw pump. The control system includes an electric motor and a motor drive. The control method includes following steps. Firstly, a DC bus voltage is monitored. If the DC bus voltage is smaller than a first threshold value, a potential energy stored in the pump screw and released by a backspin action is converted into a regenerative electrical energy so as to maintain a normal operation of the motor drive. Then, the motor drive drives the electric motor to control the backspin action of the screw pump according to a backspin torque limit strategy. If the electrical power from the power source is not restored and the level of a reverse regenerative torque is smaller than a preset torque value, the backspin action of the screw pump is stopped freely.

A motor waterproof structure includes a stator assembly, a casing and a cover body. The casing has a receiving space formed with an open side. A circuit board is disposed in the receiving space. The cover body is disposed on the open side of the receiving space to cover the circuit board. The motor waterproof structure serves to effectively protect the circuit board from being short-circuited and burned out in a humid environment.

The present disclosure relates to a method of producing a protein-containing powder including: (a) providing a protein-containing raw material; (b) freezing the protein-containing raw material at −196° C. to −80° C.; and (c) grinding the protein-containing raw material to obtain the protein-containing powder, wherein an average particle size of the protein-containing powder is smaller than a cell size of the protein-containing raw material.

This invention relates to a therapeutic composition comprising i) at least two immune checkpoint inhibitors, ii) at least one drug selected from a cytokine a cytotoxic or cytostatic chemotherapeutic drug, and combinations thereof, and iii) a cancer vaccine prepared from tumor or cancer cells, or derivatives thereof, that have been prepared through an ex vivo treatment that creates necrotic and / or necroptotic cancer cells while minimizing destruction of cancer antigens. This invention also relates to a method of treating a tumor or a cancer in a patient comprising administering to a patient in need thereof the therapeutic composition in an amount effective to treat the tumor or cancer.

The invention is an improved cementitious mixture used to form structural components that are strong, lightweight, heat and fire resistant, and very economical to produce. The material includes a mixture of cement, water, ribbon-like virgin polyethylene strips and aggregate materials. The aggregate preferably includes recycled industrial waste products. Examples of these industrial wastes include shredded tires, wood by-products, waste coal combustion by-products, recycled waste gypsum products, recycled industrial foundry sand, and waste foam products such a Styrofoam. This new cementitious material is strong and lightweight. It has a lower thermal conductivity than conventional concrete and therefore improved insulative properties. The use of industrial recyclables not only enhances the performance characteristics of the components made from this material but aids in maintaining the environment by providing a practical use for industrial waste.

The present invention relates to a smart pipette for bio-cell manipulation which can freely change orientation of a bio-cell subject to the manipulation by using mechanical friction and applying instantaneous impact when penetrating the subject bio-cell while receiving real-time feedback of force / torque information of the bio-cell. Further, the present invention relates to a bio-cell manipulation method and system using a smart pipette, through which a bio-cell may be manipulated upon the application of the force / torque information generated during the cell manipulation to the smart pipette control. According to the present invention, injection position can be recognized precisely and conveniently regardless of the proficiency of the manipulating person. Thus, the bio-cell manipulation may be automated. Further, the smart pipette quantifies force / torque information feed-backed through the sensor unit and compares it with data acquired in advance through experiments on the same bio-cell. Further, through conducting impact driving when necessary, the present invention makes it possible to conduct bio-cell manipulation with minimum physical damage.