The invention relates to a method for synchronously separating effective components in liquorice, and belongs to the fields of medicines, foods and
chemical industry. According to the method, by utilizing the
chemical structure characteristics of
flavonoid components,
triterpene components and
polysaccharide components in the liquorice as well as the
dissolution characteristics of the
flavonoid components, the
triterpene components and the
polysaccharide components in different solvents and under different pH values, the three types of the main
active components, namely, the
flavonoid components, the
triterpene components and the
polysaccharide components in the liquorice are separated synchronously. After an organic
reagent is added into an
aqueous solution of a licorice extract, by regulating the pH value of the
system to be as 7.0, the flavonoid components of the liquorice are contained in an
organic layer while the triterpene components and the polysaccharide components of the liquorice are contained in an aqueous layer; then the aqueous layer therein is separated; after the organic
reagent is added, by regulating the pH value of the
system to be as 3.0, the flavonoid components are contained in the
organic layer while the polysaccharide components are contained in the aqueous layer. As the method is used, the loss of the other effective components, caused by single or intermittent extraction and separation, is avoided; the extraction rate of the effective components as well as the yield and purity of separating the three types of the components are improved greatly after a basic
solvent is extracted. In addition, the
reagent consumption is reduced. The method is simple and easy to implement, low in
energy consumption and low in cost. Thus, the method is more suitable for industrial production.