The invention relates to the technical field of disinfection equipment for all-round internal medicine nursing instruments, and discloses a comprehensive disinfection equipment for internal medicine nursing equipment, which includes a base, a barrel body is fixedly connected to the base, a water pipe is fixedly connected to the barrel body, and the water pipe runs through the barrel The barrel body is equipped with a flushing mechanism, a turning mechanism, a rotating mechanism, a snap-fit mechanism, a fixing mechanism and a speed adjustment mechanism. The flushing mechanism includes a pipeline, a through hole, a baffle, a slider and a nozzle. The pipeline is fixedly connected to the barrel and the pipeline is connected to the barrel. The water pipe is connected, the baffle is fixedly connected to the inner wall of the pipe, the slider is fixedly connected to the outer wall of the pipe, the nozzle is slidably connected to the slider, the water flow enters the pipe through the water pipe, the water flow passes through the through hole of the baffle, and the water flow pushes the blade to drive the shaft to rotate , the rotating shaft drives the nozzle on the gear to rotate, and the rotation of the nozzle makes the water flow in the pipeline thrown out from the hole on the nozzle, increasing the impact area of the water flow and improving the cleaning effect.