The invention discloses a nasal spray cleaning device for the respiratory medicine department. The device structurally comprises a spray transmission device, a bracket, a driving mechanism, a hose joint, a telescopic hose, a nasal atomizing spray nozzle, a holding ring and a liquid storing box. Accordingly, a pressing rod can slide downwards in a straight line by pressing a pressure cap arranged on the top of the driving mechanism, and then rotation of a liquid wheel is achieved indirectly; and flushing liquid in the liquid storage box is attracted into a liquid storage bin under a waterproofpartition board, and the liquid is guided into a liquid guiding tube through liquid inlet channels arranged on the upper end and the lower end of a pressure slide block, and by means of thrust generated by the pressure slide blockwhen the liquid wheel rotates, the liquid is pressurized to be lifted into a liquid storage tank; at the moment, a lifting pump is automatically started,the flushing liquid is discharged through a liquid outlet pipe;a patient can utilize the nasal atomizing spray nozzle to flush the nasal cavity, the speed is high, the efficiency is high, and the use requirements of different patients can be met.