71results about How to "Improve outcome" patented technology

A modular prosthetic valve device for implantation in a patient is disclosed. The valve device is designed as two or more modules to be delivered unassembled and combined into an assembled valve device in the body—e.g., in the body at or near the site where implantation occurs. The two or more modules may be a support structure and a valve assembly. The valve assembly may be formed from two or more valve sections. Because the valve device of the invention is deliverable as modules, it may have a smaller delivery diameter than pre-assembled percutaneous valves and permits use of a delivery device of reduced diameter. Delivering the valve device as modules increases the flexibility of the valve device during delivery, compared to percutaneous valve devices in the art. The invention further provides a system for and method of delivering such a modular valve device and assembling it in vivo. The modules of the valve device may be connected by pull wires for delivery sequentially to or near the implantation site in the body lumen, and then assembled by remote manipulation using the pull wires. The system may further include a temporary valve that may be deployed to maintain valvular function while the device modules are assembled. The temporary valve may be attached to the delivery device and deployed either before or after the support structure is expanded, or the temporary valve may be attached to the support structure and deployed when the support structure is expanded. Various locking mechanisms are provided for attaching the device modules together.

An assembly for guiding resection of a femur and tibia of a knee joint in preparation for installing a femoral and tibial knee components. For example, the assembly can include tibial and femoral IM rods to which are connected through a tensioning bolt that allows controlled adjustment of the distraction of the tibia and femur during cut positioning in a range of flexion angles. Also, the assembly is usable with relatively small, noninvasive approaches to the knee joint by way of relatively narrow, low profile components that attach to tibial and femoral IM rods. Further, the assembly includes several quick-release components to allow fast assembly and disassembly in a surgical setting. Each of these aspects, along with the ability of the assembly to accurately guide initial reference cuts to the tibia and femur, promotes an improved outcome for the patient.

A method, system, and computer software product for correlating medical images, comprising: obtaining first image data representative of a first medical image including a first abnormality; obtaining second image data representative of a second medical image including a second abnormality; determining at least one feature value for each of the first and second abnormalities using the first and second image data; calculating, based on the determined feature values, a likelihood value indicative of a likelihood that the first and second abnormalities are a same abnormality; and outputting the determined likelihood value.

The invention relates to methods of diagnosing or monitoring a psychotic disorder in a subject comprising providing a test biological sample from the subject, performing spectral analysis on said test biological sample to provide one or more spectra, and, comparing the one or more spectra with one or more control spectra. The invention also relates to methods for diagnosing or monitoring psychotic disorders such as schizophrenic or bipolar disorders, comprising measuring the level of one or more biomarkers present in a biological sample taken from a test subject, said biomarkers being selected from the group consisting of transthyretin, ApoA1: VLDL, LDL and aromatic species such as plasma proteins. The invention also relates to sensors, biosensors, multi-analyte panels, arrays, assays and kits for performing methods of the invention.

An image data correction apparatus has a motion information acquisition section, a correction section, and a composition section. The motion information acquisition section acquires motion information indicating spatial distribution of the magnitude of motion, in actual space, of a to-be-imaged portion of a subject. Based on the motion information, the correction section performs correction, which is different from correction in a second region, in a first region of image data collected by a scan by magnetic resonance imaging. The composition section composes individual image data of the first region and the second region that are corrected by the correction section.

The present invention includes compositions and methods of reducing the glycosylation of proteins comprising: obtaining a cell that expresses one or more proteins that comprise one or more glycosylation sites and are glycosylated; expressing in the cell one or more glycosidases that cleaves one or more glycosyl groups from the one or more proteins; and isolating the one or more proteins with reduced glycosylation from the cell.

The invention relates to data searching and translation. In particular, the invention relates to searching documents from the Internet or databases. Even further, the invention also relates to translating words in documents, WebPages, images or speech from one language to the next. A computer implemented method including at least one computer in accordance with the invention is characterised by the following steps:receiving a search query including at least one search term, deriving at least one synonym for at least one search term, expanding the received search query with the at least one synonym, searching at least one document using the expanded search query, retrieving the search results obtained with the expanded query, ranking the search results based on context of occurrence of at least one search term. The best mode of the invention is considered to be an Internet search engine that delivers better search results.