The invention relates to the technical field of medical compression patches, in particular to a self-heating medical hot-compression patch for rheumatic pain and a method for manufacturing the self-heating medical hot-compression patch. The self-heating medical hot-compression patch comprises a non-woven cloth bag, a heating layer and a pressure-sensitive adhesive tape. The heating layer is arranged in the non-woven cloth bag, the pressure-sensitive adhesive tape is used for fixing the non-woven cloth bag, the heating layer comprises, by weight, 45-55% of reduced iron powder, 10-18% of activated carbon, 0.1-5% of high-polymer water-absorbent resin, 1-7% of sodium chloride and 25-38% of traditional Chinese medicine extracting solution, and the traditional Chinese medicine extracting solution comprises harlequin glorybower leaves and twigs, herba siegesbeckiae, air-plant herb, curcuma zedoary, radix angelicae pubescentis and asarum sieboldii. The self-heating medical hot-compression patch and the method have the advantages that thermal therapy and traditional Chinese medicine therapy are combined with each other, accordingly, excellent foundation is laid for rheumatic pain therapy, and physiotherapy and therapy effects further can be realized for inflammation and diseases due to rheumatic arthritis, back and leg pain, cervical spondylosis, lumbar muscle strain, lumbar disc herniation, scapulohumeral periarthritis, hyperostosis, sciatica, rheumatic pain, knee joint injury and the like.