The present invention relates to a
medicine management system and a
processing method thereof, and more particularly, to a
medicine management system and a
processing method thereof, in which using a
robot unit, the replenishment of medicines is conveniently implemented by moving an empty cassette of an automatic
medicine packing apparatus and then mounting the automatic medicine packing apparatus with a new cassette which is kept in a medicine storage unit and in which the corresponding medicines are accommodated. To this end, there is provided with a medicine
management system, comprising: a medicine storage unit for keeping at least one cassette in which medicines are accommodated; a
robot unit moving along a predetermined
robot movement line and including a gripper for gripping the cassette; an automatic medicine packing apparatus for packing medicines according to a preparation request data externally received and for requesting replenishment of medicines when there is no medicine in the cassette; and a central
control unit for controlling the robot unit to transmit
movement control commands to the robot unit when the automatic medicine packing apparatus requests the cassette to be replenished with the medicines so that the cassette requested to be replenished with the medicines is gripped in the automatic medicine packing apparatus and transferred to a conveyer and a new cassette in which the corresponding medicines are accommodated is gripped in the medicine storage unit and mounted to the automatic medicine packing apparatus.