51results about How to "Alleviate the cause" patented technology

Engineered protein kinases which can utilize modified nucleotide triphosphate substrates that are not as readily utilized by the wild-type forms of those enzymes, and methods of making and using them. Modified nucleotide triphosphate substrates and methods of making and using them. Methods for using such engineered kinases and such modified substrates to identify which protein substrates the kinases act upon, to measure the extent of such action, and to determine if test compounds can modulate such action. Also engineered forms of multi-substrate enzymes which covalently attach part or all of at least one (donor) substrate to at least one other (recipient) substrate, which engineered forms will accept modified substrates that are not as readily utilized by the wild-type forms of those enzymes. Methods for making and using such engineered enzymes. Modified substrates and methods of making and using them. Methods for using such engineered enzymes and such modified substrates to identify the recipient substrates the enzymes act upon, to measure the extent of such action, and to measure whether test compounds modulate such action.

Engineered protein kinases which can utilize modified nucleotide triphosphate substrates that are not as readily utilized by the wild-type forms of those enzymes, and methods of making and using them are disclosed. Modified nucleotide triphosphate substrates and methods of making and using them are disclosed. Methods are disclosed for using such engineered kinases and such modified substrates to identify which protein substrates the kinases act upon, to measure the extent of such action, and to determine if test compounds can modulate such action. Engineered forms of multi-substrate enzymes which covalently attach part or all of at least one (donor) substrate to at least one other (recipient) substrate, which engineered forms will accept modified substrates that are not as readily utilized by the wild-type forms of those enzymes are disclosed. Methods for making and using such engineered enzymes are disclosed. Modified substrates and methods of making and using them are disclosed. Methods are disclosed for using such engineered enzymes and such modified substrates to identify the recipient substrates the enzymes act upon, to measure the extent of such action, and to measure whether test compounds modulate such action.

First laser light is irradiated (energy density of 400 to 500 mj / cm2) to a semiconductor film 102 in an atmosphere containing oxygen in order to obtain a semiconductor film 102b having large depressions and projections on the surface. Then, an oxidized film 105a formed by the irradiation of the first laser light is removed. After that, an inert gas with an oxygen density of 10 ppm or below is blown thereto, and, at the same time, second laser light is irradiated thereto (the energy density is higher than that of the irradiation of the first laser light). Thus, the surface of the semiconductor film 102b is flattened, and a semiconductor film 102c having fewer depressions and projections on the surface can be obtained.

A drive arrangement for the drive of an agricultural implement is provided that includes a drive engine that can be brought into a drive connection over a separable power take-off shaft clutch with a power take-off shaft output. A drive line of the operating implement is connected with the power take-off shaft output, with an overload clutch, and a control arrangement. The control arrangement is connected to a sensor arranged for the detection of the torque at the power take-off shaft output and, in normal operation, permits an actuator to disengage the power take-off shaft clutch as soon as the torque detected by the sensor reaches or exceeds a first threshold value, that corresponds to a torque that is smaller than the cut-off torque of the overload clutch. Immediately following, the control arrangement orders the actuator to engage the power take-off shaft clutch and when the power take-off shaft clutch is disengaged permits a torque at the power take-off shaft output that is greater than the cut-off torque of the overload clutch.

Selected strains of Lactobacillus and products containing cells of the selected strains to improve breast milk for feeding to babies, more precisely to increase the levels of the anti-inflammatory cytokine IL10 in the milk and reduce the risk that the feeding baby will develop allergies and simultaneously reduce the cause and thereby the amount of TGF-beta-2 in the milk, thus resulting in reduced risk for the lactating mother to develop mastitis.

A system and method for damping undesired motion of a suspended structure that is connected by one or more flexures that have an elastic limit to a fixed structure in a MEMS sensor, wherein the undesired motion is caused by a high G acceleration pulse. At one or more of before and during a high G acceleration pulse that could move the suspended structure beyond the elastic limit of a flexure, the system actively generates an attractive force that acts to counteract motion of the suspended structure caused by the high G acceleration pulse, so as to maintain motion of the suspended structure within the elastic limit of the flexure.

This invention relates to a system and method for the management, more particularly by external, transparent and non-intrusive control, of the running of one or more software tasks within a multi-task application executed on a computer or a network of computers. This management comprises in particular a recording of the running of these tasks in the form of logging data, as well as a replay of this running from such logging data in order to present a behaviour and a result corresponding to those obtained while logging.The invention also relates to a system implementing such a method in the management of the functioning of the software applications that it executes.

The invention provides a light emitting device using transistors manufactured by the conventional process while reducing an area occupied by capacitors, whereby variations in luminance of light emitting elements caused by variations in gate voltage Vgs of the transistors are suppressed, and a luminance decay of the light emitting elements due to the degradation of light emitting materials and variations in luminance can also be suppressed. The light emitting device includes a first transistor for controlling a video signal input to a pixel, second and third transistors one of which is turned ON while the other is turned OFF according to a potential of the video signal, and a fourth transistor for supplying current to a light emitting element according to each drain potential of the second and third transistors, wherein the drains of the second and third transistors are connected to each other, the third and fourth transistors have the same conductivity, and the sources of the third and fourth transistors are connected to each other.

A substrate treatment apparatus, comprising a box-shaped treatment tank (11) having an opening part at its upper side and a cover body (21) openably covering the opening part of the treatment tank. The cover body (21) is characterized in that a drying chamber (23) storing and drying a treated substrate (W) is formed therein, the treatment tank (11) is so formed that at least three of treatment fluid feed nozzle tubes (14a) to (14c) and (14a′) to (14c′) are disposed at each of the opposed side wall faces thereof forming the box shape horizontally at specified intervals and these feed nozzle tubes (14a) to (14c) and (14a′) to (14c′) are formed to be connected to a switching mechanism to supply a treatment fluid from the opposed side wall sides while alternately switching them at the opposed side wall faces. Thus, the treatment of various types of chemical liquids, flushing, and drying can be performed in the same treatment tank.

A reverse osmosis membrane apparatus 17 including an RO membrane 17a that yields recycled water 18 and concentrated water 19 from pre-treated raw water (inflow water 16), salts being removed in the recycled water and salts being concentrated in industrial park waste water 11; monitoring apparatuses 21A and 21B disposed at an inflow water line L1 through which the inflow water 16 flows into the reverse osmosis membrane apparatus 17 or a concentrated water line L2 through which the concentrated water 19 flows out from the reverse osmosis membrane apparatus 17, which monitor the presence of chemical fouling causal substances in the inflow water 16 or the concentrated water 19; and a chemical supply section 22, which is a removal apparatus that removes the chemical fouling causal substances from the inflow water 16 on the front upstream side of the inflow into the reverse osmosis membrane apparatus 17, upon the presence of chemical fouling causal substances in the inflow water 16 or the concentrated water 19 being confirmed. Thus, the chemical fouling preventing system removes chemical fouling causal substance from inflow water 16 before it enters the reverse osmosis membrane apparatus 17.

A heating device utilizing electromagnetic induction is provided with an induction heating unit that is opposed to a heating member and causes the heating member to heat through electromagnetic induction. The induction heating unit has an exciting coil for generating a magnetic field and a coil guide member on which the exciting coil is wound. The exciting coil is formed in at least two layers in such a manner that a first layer is formed on a circumferential surface of the coil guide member by winding a plurality of turns and a second layer is formed around and outside the first layer on the side opposite to the coil guide member, and winding of each of the second layer and following layers is started from a position close to a winding start position of the first layer.

The invention discloses a traditional Chinese medicine composition for treating hyperlipemia and hyperglycemia, and relates to the field of a traditional Chinese medicine. The traditional Chinese medicine composition is prepared from the following raw materials: 10-20 parts of burdock, 12-18 parts of common yam rhizome, 6-10 parts of semen cassia, 10-15 parts of rhizoma alismatis, 10-20 radix curcumae longae, 12-16 parts of tuckahoe, 6-9 parts of lithospermum, 20-30 parts of caulis spatholobi, 20-30 parts of hawthorn, 10-16 parts of radix bupleuri, 12-18 parts of parasitic loranthus, 15-25 parts of lotus leaf, 10-20 parts of giant knot weed, 6-12 parts of radix paeoniae alba, 15-20 parts of achyranthes root, and 10-15 parts of liquorice. The traditional Chinese medicine composition disclosed by the invention has a good treatment effect in the aspect of treatment of hyperglycemia and / or hyperlipidemia, especially on a sufferer with hyperlipidemia and hyperglycemia, and has significant clinical popularization value.

The invention belongs to the field of traditional Chinese medicines, relates to an application of traditional Chinese medicine composition in preparation of a medicine for treating hyperuricemia. In order to overcome the conventional technical defects that at present, hyperuricemia complicated with hepatic calculus cannot be treated comprehensively and effectively, meanwhile, is prone to relapse with a chemical treatment method, and the curative effect cannot last, the invention provides the traditional Chinese medicine composition which comprises components as follows: 9-21 parts of lonicera japonica, 11-19 parts of rhizoma phragmitis, 5-11 parts of rhizoma zingiberis, 9-16 parts of anemarrhena asphodeloides, 9-21 parts of pinellia ternate, 11-17 parts of radix polygoni multiflori preparata, 5-10 parts of corydalis yanhusuo, 19-31 parts of atractylodes lancea, 19-31 parts of raw semen coicis, 9-17 parts of rhizoma alismatis, 11-19 parts of poria cocos, 14-26 parts of hairyvein agrimonia, 9-21 parts of rhizoma cyperi, 5-13 parts of rosa banksiae, 14-21 parts of lotus leaves and 9-16 parts of liquorice. The traditional Chinese medicine composition has a good treatment effect on hyperuricemia complicated with hepatic calculus and has remarkable clinical popularization value.

Provided is a device for limiting a current of electric appliance. The current limiting device includes: at least two loads; at least two load driving units connected to the loads to control applying power to the loads; a power detecting unit detecting a power type; a micom controlling the load driving unit according to the power type detected by the power detecting unit to drive the load using a current flowing into the load within an allowable value; and at least one current limiting unit connected to at least one control line connecting the micom and the load driving unit and limiting a current of the load driving unit connected to the control line when the micom malfunctions by using a control signal of the micom and a signal of the power type detected from the power detecting unit as an input signal.

A flavoring solution for making pickles having a flavor of foods pickled in rice bran paste, a clear bran pickles flavoring solution, processes for producing the flavoring solutions, a process for producing lactones which are essential components of the flavoring solutions, and a bacterium belonging to the genus Corynebacterium which is useful for producing a lactone are disclosed. The bacterium is preferably Corynebacterium sp. NK-1 (FERM BP-6329). The lactone is preferably a gamma lactone.

Disclosed is a portable internet system, and more particularly, to a method of supporting fast ranging upon handover. The method comprises calculating an action time based on a time when a handover confirmation message is received from a serving Radio Access Station (RAS), in a target RAS; and transmitting a fast ranging information message to a mobile station on the basis of the action time.

The foot fulcrum orthotic includes a semi-compressible ring and attachment method to the foot. When worn around the midfoot, said semi-compressible ring forms a fulcrum to raise the ball of the foot up off the mattress and provides compression relief to the ball of the foot. This compression relief, when combined with other treatments, speeds the healing of metatarsalgia including Morton's neuroma, corns, calluses, and bunions. A plurality of ring styles are disclosed including continuous (FIGS. 7A, 7B, 7C), non-continuous (FIGS. 3, 4, 6A, 6B) with a gap for foot circumference size adjustment. A plurality of attachment methods are disclosed including single heel straps (FIGS. 7A, 7B, 7C), multiple heel straps (FIGS. 3, 4), socks (FIGS. 10A, 10B, 10C, 11A, 11B), and single-piece molded boot (FIGS. 9A, 9B).

The present invention provides a crystalline Form A of Compound 1, also referred to as Granaticin B, and pharmaceutically compositions thereof. The present invention also provides methods of treating a microbial infection, or a disease, disorder, or condition associated with abnormal cellular proliferation, using crystalline Form A of Compound 1 or pharmaceutical compositions thereof.

A substantially hollow wingsail is configured to enable electrical components to be situated within the wingsail. In particular, the wingsail may be configured to contain the solar panels used to power the other electrical components of the vessel, as well as other items that are conventionally situated on the exterior of the vessel, such as antennas, navigation lights, and so on. The surface of the wingsail may include transparent or translucent areas to provide light to the solar panels, as well as optical and electromagnetic reflective areas within the wingsail to enhance the performance of the solar panels and antennas. The wingsail may also include an internal light that illuminates the translucent areas of the wingsail for enhanced visibility to other vessels.

The invention belongs to the field of medicines, and relates to a traditional Chinese medicinal composition for treating hyperthyroidism, and a preparation method and application thereof. The traditional Chinese medicinal composition is prepared from the following traditional Chinese medicinal materials in parts by weight: 10-20 parts of morinda officinalis, 12-18 parts of sculellaria barbata, 6-10 parts of semen cassiae, 10-15 parts of paniculate swallowwort root, 10-20 parts of ligusticum wallichii, 12-16 parts of wild chrysanthemum flower, 6-9 parts of salviae miltiorrhizae, 20-30 parts of momordica grosvenori, 20-30 parts of astragalus membranaceus, 10-16 parts of radix bupleuri, 12-18 parts of poria cocos, 15-25 parts of scutellaria baicalensis, 10-20 parts of tribulusterrestris, 6-12 parts of radix paeoniae alba, 15-20 parts of rhizoma atractylodis macrocephalae and 10-15 parts of liquorice. The traditional Chinese medicinal composition has the advantages of exact curative effect and low side effect when being used for treating hyperthyroidism.

The invention makes secure the processing of a signal (Se) delivered by a sensor (2) of resistive analog type, in a safety device, the signal (Se) being converted into a digital signal (n) in an analog / digital converter (4) of resolution (R). A digital signal (n1) is acquired and stored, then the supply voltages (Va, Vb) of the sensor (2) are inverted (at 8) and a new digital signal (n2) is acquired. The two signals (n1, n2) are summed, and their sum (S) is compared with the resolution (R) of the converter (4). Depending on whether the sum (S) is or is not equal to the resolution (R), the control (Cm) of an actuator (6), corresponding to a pre-set (Sc), is enabled or otherwise.Application to tower crane safety devices.

Engineered protein kinases which can utilize modified nucleotide triphosphate substrates that are not as readily utilized by the wild-type forms of those enzymes, and methods of making and using them. Modified nucleotide triphosphate substrates and methods of making and using them. Methods for using such engineered kinases and such modified substrates to identify which protein substrates the kinases act upon, to measure the extent of such action, and to determine if test compounds can modulate such action. Also Engineered forms of multi-substrate enzymes which covalently attach part or all of at least one (donor) substrate to at least one other (recipient) substrate, which engineered forms will accept modified substrates that are not as readily utilized by the wild-type forms of those enzymes. Methods for making and using such engineered enzymes. Modified substrates and methods of making and using them. Methods for using such engineered enzymes and such modified substrates to identify the recipient substrates the enzymes act upon, to measure the extent of such action, and to measure whether test compounds modulate such action.

The present invention provides cosmetics or external preparations for skin are provided that contain, as the effective ingredient, a chemical peeling agent, a bactericide, an anionic surfactant or a cationic surfactant component in combination with a cystine derivative of formula (1):