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37results about How to "Ability to efficiently" patented technology
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Oligonucleotides with alternating segments of locked and non-locked nucleotides
ActiveUS7687617B2Increased Design PossibilitiesEfficient substrateSugar derivativesActivity regulationNucleotideThio-
Owner:SANTARIS PHARMA AS
Antisense design
ActiveUS20060128646A1Efficient deliveryAiding diffusionOrganic active ingredientsPeptide/protein ingredientsThio-Locked nucleic acid
A novel class of pharmaceuticals which comprises a Locked Nucleic Acid (LNA) which can be used in antisense therapy. These novel oligonucleotides have improved antisense properties. The novel oligonucleotides are composed of at least one LNA selected from beta-D-thio / amino-LNA or alpha-L-oxy / thio / amino-LNA. The oligonucleotides comprising LNA may also include DNA and / or RNA nucleotides.
Owner:ROCHE INNOVATION CENT COPENHAGEN
Tarsal joint space distractor
InactiveUS7097647B2Easy to useAbility to efficientlyProsthesisOsteosynthesis devicesDistractionMedicine
This disclosure relates to an improved dual axis surgical retractor for use by orthopedic or podiatric surgeons for controlled distraction of tarsal joints or compression of osseus fragments. This retractor generally consists of a pair of screw actuated retractor arms, the tips of which each have apertures for receiving and facilitating temporary pin fixation of the respective tarsal bones to be retracted or osseus fragments to be compressed.
Owner:SEGLER CHRISTOPHER PAIGE
Methods, devices and systems for assessing eye disease
Methods and devices for detecting eye disease and for assessing the clinical stage of an eye disease in an individual. The methods include projecting test patterns onto the retina of a tested eye and subjecting the individual to a competing sensory stimuli. The competing stimuli may be of various different sensory modalities including visual, auditory, or other sensory modalities. If the individual perceives a difference in at least one localized part of the perceived image of a test pattern as compared to a predefined reference pattern, the individual provides a response indicative of the difference or differences. The responses are processed to assess the severity of eye disease if a disease is detected, or to determine the clinical stage of a detected eye disease.
Owner:NOTAL VISION
Method and system for assessing eye disease
Methods and a device comprising a controller / processor unit (664), a visual test-pattern unit (660), a competing sensory stimuli generating unit (662), a user input device (666), an ouput device (668) and a storage unit (670) for detecting eye disease and for assessing the clinical stage of an eye disease in an individual is disclosed. The methods include projecting test patterns onto the retina of a tested eye and subjecting the individual to a competing sensory stimuli. The competing stimuli may be of various different sensory modalities including visual, auditory, or other sensory modalities. If the individual perceives a difference in at least one localized part of the perceived image of a test pattern as compared to a predefined reference pattern, the individual provides a response indicative of the difference or differences. The responses are processed to assess the severity of eye disease if a disease is detected, or to determine the clinical stage of a detected eye disease.
Owner:NOTAL VISION
Polymer coating blends
InactiveUS7132170B2Improve adhesionAbility to efficientlyPedestrian/occupant safety arrangementFibre typesPolymer sciencePolymer coatings
An adhesive coating composition for fabric substrates, such as automotive airbags. The coating is formed from a blend including a silicone polymer and a second polymer which is thermodynamically compatible with silicone. In particular, the second polymer has a cohesion parameter (δ / MPa1 / 2) that is similar to that of silicone so that any thermodynamic barrier to the second polymer dissolving in silicone is removed.
Owner:MILLIKEN & CO
Method, system, software, and signal for automatic generation of macro commands
InactiveUS7421654B2Ability to efficientlyTelevision system detailsResonant circuit detailsSoft keyGraphics
Owner:GATEWAY
Oligonucleotides with alternating segments of locked and non-locked nucleotides
ActiveUS20090209748A1Increased Design PossibilitiesEfficient substrateOrganic active ingredientsSugar derivativesThio-Nucleotide
The present invention is directed to novel oligonucleotides with improved antisense properties. The novel oligonucleotides comprise at least one Locked Nucleic Acid (LNA) selected from beta-D-thio / amino-LNA or alpha-L-oxy / thio / amino-LNA. The oligonucleotides comprising LNA may also include DNA and / or RNA nucleotides. The present invention also provides a new class of pharmaceuticals which comprise antisense oligonucleotides and are useful in antisense therapy.
Owner:SANTARIS PHARMA AS
Medical irradiation apparatus
A medical irradiation apparatus comprising a main body, a luminous body comprised of a light emitting element provided in a light outlet of the main body, an annular reflective member with a reflective surface provided at the circumference of the luminous body, the reflective surface reflecting the light from the luminous body forward, and a lens member provided so as to cover a forward opening of the reflective member, the lens member refracting and transmitting the direct light from the luminous body and the light reflected from the reflective member. According to the apparatus, all the outgoing light from the lens member is emitted so as to direct into a specified irradiation area.
Owner:MORITA MFG CO LTD
Thermal sealing packaging systems and methods for thermal sealing packaging
ActiveUS20110023421A1Complete efficientlyShort timeWrapping material feeding apparatusPackaging cigaretteEngineeringMechanical engineering
A thermal seal packaging systems and methods thereof. In one implementation a thermal sealing packaging system has a container transfer unit for transferring a container which is to contain a package item, a measuring unit for measuring the weight of the item that is loaded in the container being transported before it is loaded into the container, a capping film supply unit for a capping film to cover the opening area of the container, an indication means for indicating the measurement data of the measurement unit on the capping film, and a sealing unit for heat-sealing an opening area of the container, into which the package item is loaded, with the capping film, the opening area of the container into which the item is loaded is covered by the capping film on which the corresponding measurement data is indicated.
Owner:ULMA PACKAGING SCOOP +1
Triglyceride fat
ActiveUS20040071856A1Great tasteAbility to efficientlyFatty acid esterificationEdible oils/fats production/working-upTriglycerideChain length
Process for the preparation of an edible triglyceride fat which is able to structure a liquid oil which process comprises the steps selecting a triglyceride fat A and a triglyceride fat B, interesterifying a mixture containing fat A and fat B in a ratio chosen from the range 80:20 to 20:80, where fat A is a fat which is natural and which contains at least 35 wt. % of stearic acid residues and less than 5 wt. % residues of polyunsaturated fatty acids and where fat B contains at least 40 wt. % of saturated fatty acid residues with a chain length of 12 or 14 carbon atoms and which process is characterized in that fat A is selected from the group consisting of Allanblackia fat, Pentadesma fat, Kokum fat and Sonchy fat. The resulting fat enables the preparation of a natural fat phase for use in spread manufacture.
Owner:UNILEVER BESTFOODS NORTH AMERICA DIV OF CONOPCO
Filter having opposing parallel planes of wedge wires
InactiveUS20080073298A1Efficient backwashingLarge throughputFluid removalWater/sewage treatmentEngineeringMechanical engineering
A screen for separating solids and liquids is formed from parallel strips of wedge wire or similar material into a two-sided enclosure having the flat bases of the wedge wires oriented to contact dirty liquid. Unfiltered liquid containing solids contacts the screen surface on both sides of the enclosure, forming a passage for filtrate. A wedge wire screen may be bent back on itself to form a C-shape or may be a closed curve, still exposing only the flat sides of the wedge wires to the dirty liquid, and collection filtrate within the enclosure so formed. Filter units may be placed in a housing adapted to accommodate two or more in a substantially concentric relationship.
Owner:TOTAL SEPARATION SOLUTIONS
Engine revolution controller of working machine
InactiveUS20070125341A1Maintenance of such closeSuppress increaseElectrical controlInternal combustion piston enginesIgnition timingThrottle opening
In an engine of a working machine having no governor mechanism, the engine revolution speed is controlled such that the revolution speed can stably be maintained irrespective of the variation in load without adjusting the throttle opening to exploit the full potential of the engine. Since an engine 1 does not have the governor mechanism, an operator adjusts the throttle opening and controls the engine revolution speed. A map in which ignition timing (amount of angle of lead) is set by means of functions of the engine revolution speed is stored in an ignition timing map 30. The map 30 is set such that the engine revolution speed is equal to or higher than a value to be controlled (e.g. 7000 rpm), and the ignition timing is lagged as compared with a case in which the engine revolution speed is lower than the value to be controlled.
Owner:HONDA MOTOR CO LTD
Methods and systems for handling currency
A bulk deposit can be made at a financial institution based on dealings between a remitter and the remitter's agent. Information concerning transactions between the agent and the agent's customers, is transferred by the agent to the remitter and, in turn, from the remitter to a service provider that is distinct from the agent, the remitter, and the remitter's bank. The service provider can generate a deposit slip and store in a database, information about the slip. This deposit slip is marked with (a) transaction amounts for the agent's customers, (b) the bulk cash to be deposited; and (c) a summary of any discrepancy between the two. The provider makes available to the financial institution at least some of the transaction information including (a) its correlation to the deposit slip, and (b) detail greater than that produced on the deposit slip.
Owner:DEPOSITSLIPS
Polymer coating blends
InactiveUS20050025985A1Cost reductionEnhance coatingFibre typesPedestrian/occupant safety arrangementAirbag deploymentSiloxane
An adhesive coating composition for fabric substrates, such as automotive airbags. The coating is formed from a blend including a silicone polymer and a second polymer which is thermodynamically compatible with silicone. In particular, the second polymer has a cohesion parameter (δ / MPa1 / 2) that is similar to that of silicone so that any thermodynamic barrier to the second polymer dissolving in silicone is removed.
Owner:MILLIKEN & CO
Novel Phospholipase C Enzyme (S)
The present invention provides a phospholipase C enzyme(s) having ability to hydrolyze phospholipid in both acidic and around neutral ranges and the activity in a citrate buffer solution as well as having some degree of heat stability, and having a property not to hydrolyze phosphate esters not containing lipid moieties. The phospholipase C enzyme(s) shows the activity at from acidic to neutral pH and does not substantially hydrolyze any phosphate esters except for phospholipids.
Owner:MITSUBISHI CHEM CORP
Method of preparing cell for bone tissue formation and application of cell for bone tissue formation
InactiveUS20090298173A1High treatment effectEasy to operateCell differentiationSkeletal disorderBone tissueTherapeutic effect
It is intended to provide a method of efficiently and stably preparing a cell having a bone tissue formation ability by a simple operation. Further, it is intended to provide a method of preparing a composition for bone tissue formation with high safety and an excellent therapeutic effect by a simple operation. The cell for bone tissue formation is obtained by (1) culturing bone marrow after isolating it from a living body, diluting it at a predetermined dilution ratio and inoculating it to a culture vessel, (2) culturing the remaining adhesive cells after removing floating components, (3) inducing differentiation of proliferated cells to bone cells and (4) recovering the cells. The thus obtained cells, a thrombin solution, platelet-rich plasma and air are mixed at a predetermined mixing ratio (based on volume) in the presence of calcium ions and the mixture is gelled, whereby a gelled composition is obtained.
Owner:UEDA MINORU +2
Concentric C-shaped filter and screen topology
InactiveUS20060201873A1Sustainable throughputAbility to efficientlyFluid removalLoose filtering material filtersEngineeringMechanical engineering
A screen for separating solids and liquids is formed from parallel strips of wedge wire or similar material into a substantially cylindrical two-sided enclosure in a generally C-shaped profile. Unfiltered liquid containing solids contacts the screen surface on both the convex and concave sides of the C-shaped enclosure. The unit may be placed in a vessel adapted to accommodate two such C-shaped devices in concentric relationship. The vessel may function similar to a candle filter, or a more conventional flow may be used.
Owner:TOTAL SEPARATION SOLUTIONS
Efficient on-chip instruction and data caching for chip multiprocessors
The storage of data line in one or more L1 caches and / or a shared L2 cache of a chip multiprocessor is dynamically optimized based on the sharing of the data line. In one embodiment, an enhanced L2 cache directory entry associated with the data line is generated in an L2 cache directory of the shared L2 cache. The enhanced L2 cache directory entry includes a cache mask indicating a storage state of the data line in the one or more L1 caches and the shared L2 cache. In some embodiments, where the data line is stored in the shared L2 cache only, a portion of the cache mask indicates a storage history of the data line in the one or more L2 caches.
Owner:ORACLE INT CORP
Two level packet distribution with stateless first level packet distribution to a group of servers and stateful second level packet distribution to a server within the group
ActiveUS8825867B2Easy to handleAbility to efficientlyData switching by path configurationMultiple digital computer combinationsData packDistribution system
A method, in one or more network elements that are in communication between clients that transmit packets and servers, of distributing the packets among the servers which are to process the packets. Stickiness of flows to servers assigned to process them is provided. A packet of a flow is received at a static first level packet distribution module. A group of servers is statically selected for the packet of the flow with the first level module. State that assigns the packet of the flow to the selected group of servers is not used. The packet of the flow is distributed to a distributed stateful second level packet distribution system. A server of the selected group is statefully selected with the second level system by accessing state that assigns processing of packets of the flow to the selected server. The packet of the flow is distributed to the selected server.
Owner:TELEFON AB LM ERICSSON (PUBL)
Thick steel sheet having excellent CTOD properties in multilayer welded joints, and manufacturing method for thick steel sheet
ActiveUS20160017456A1Good multipass weld joint CTOD characteristicAvoid grain growthFurnace typesWelding/cutting media/materialsSteel platesOxide
There is provided a thick steel plate having good multipass weld joint CTOD characteristics for low to medium heat input and a method for manufacturing the thick steel plate. A steel plate containing, on a mass percent basis, C: 0.03% to 0.12%, Si: 0.5% or less, Mn: 1.0% to 2.0%, P: 0.015% or less, S: 0.0005% to 0.0050%, Al: 0.005% to 0.060%, Ni: 0.5% to 2.0%, Ti: 0.005% to 0.030%, N: 0.0015% to 0.0065%, O: 0.0010% to 0.0050%, Ca: 0.0005% to 0.0060%, and optionally one or two or more of Cu and the like, wherein Ti / N, Ceq, Pcm, and ACR are in particular ranges, a base material of the plate has an effective grain size of 20 μm or less at half the thickness of the plate, and the plate contains a particular number of complex inclusions at ¼ and ½ of the thickness of the plate, the complex inclusions being composed of a sulfide containing Ca and Mn and an oxide containing Al and having an equivalent circular diameter of 0.1 μm or more. Steel having the composition described above is heated at a particular temperature, is then hot-rolled, and is cooled.
Owner:JFE STEEL CORP
Phospholipase C enzyme(s)
The present invention provides a phospholipase C enzyme(s) having ability to hydrolyze phospholipid in both acidic and around neutral ranges and the activity in a citrate buffer solution as well as having some degree of heat stability, and having a property not to hydrolyze phosphate esters not containing lipid moieties. The phospholipase C enzyme(s) shows the activity at from acidic to neutral pH and does not substantially hydrolyze any phosphate esters except for phospholipids.
Owner:MITSUBISHI CHEM CORP
Active Sunscreen Composition
InactiveUS20100021400A1Prevents DNA damageInduces DNA repairCosmetic preparationsToilet preparationsChemical compositionFluorescence
The invention relates to topical compositions comprising a fluorescent dye that absorbs UVA and UVB radiation and converts it into a healing light, in combination with a dermatologically acceptable excipient. The compositions of the invention are useful for repairing photo-damaged skin cells and reducing or preventing future skin damage as a result of exposure to UV light.
Owner:RHODE ISLAND HOSPITAL
Concentric C-shaped filter and screen topology
InactiveUS7448501B2Sustainable throughputAbility to efficientlyFluid removalLoose filtering material filtersEngineeringMechanical engineering
A screen for separating solids and liquids is formed from parallel strips of wedge wire or similar material into a substantially cylindrical two-sided enclosure in a generally C-shaped profile. Unfiltered liquid containing solids contacts the screen surface on both the convex and concave sides of the C-shaped enclosure. The unit may be placed in a vessel adapted to accommodate two such C-shaped devices in concentric relationship. The vessel may function similar to a candle filter, or a more conventional flow may be used.
Owner:TOTAL SEPARATION SOLUTIONS
Thick steel sheet having excellent CTOD properties in multilayer welded joints, and manufacturing method for thick steel sheet
ActiveUS10036079B2Avoid grain growthImprove toughnessFurnace typesWelding/cutting media/materialsSheet steelMaterials science
There is provided a thick steel plate having good multipass weld joint CTOD characteristics for low to medium heat input and a method for manufacturing the thick steel plate. A steel plate containing, on a mass percent basis, C: 0.03% to 0.12%, Si: 0.5% or less, Mn: 1.0% to 2.0%, P: 0.015% or less, S: 0.0005% to 0.0050%, Al: 0.005% to 0.060%, Ni: 0.5% to 2.0%, Ti: 0.005% to 0.030%, N: 0.0015% to 0.0065%, O: 0.0010% to 0.0050%, Ca: 0.0005% to 0.0060%, and optionally one or two or more of Cu and the like, wherein Ti / N, Ceq, Pcm, and ACR are in particular ranges, a base material of the plate has an effective grain size of 20 μm or less at half the thickness of the plate, and the plate contains a particular number of complex inclusions at ¼ and ½ of the thickness of the plate, the complex inclusions being composed of a sulfide containing Ca and Mn and an oxide containing Al and having an equivalent circular diameter of 0.1 μm or more. Steel having the composition described above is heated at a particular temperature, is then hot-rolled, and is cooled.
Owner:JFE STEEL CORP
Fluid injection deflector shield viewing apparatus and method
InactiveUS20090175686A1Improve visualizationImprove visibilityOperating means/releasing devices for valvesWater cleaningFluid transportVisibility
A fluid injection deflector shield viewing apparatus with a deflector shield, a fluid concentrating focal area on one side of the deflector shield, an anchoring means to secure the deflector shield in the desired location, a fluidic material of decreased visibility, an observation means, a filtration system to filter the fluidic material, an intake to take in the fluidic material of decreased visibility, a discharge for introducing the filtered fluidic material into the fluid concentrating focal area on one side of the deflector shield, and a fluid transport means to transport the filtered fluidic material to the discharge. A preferred embodiment includes having a moving anchoring system so as to change the position of the deflector shield. A preferred embodiment includes a means for moving the anchoring system so as to change the position of the deflector shield comprised of a plurality of self propelled thrusters.
Owner:KRUGER TORSTEN
Methods and systems for handling currency
ActiveUS8676700B2Reduce deliveryAbility to efficientlyComplete banking machinesFinanceService provisionFinancial transaction
A bulk deposit can be made at a financial institution based on dealings between a remitter and the remitter's agent. Information concerning transactions between the agent and the agent's customers, is transferred by the agent to the remitter and, in turn, from the remitter to a service provider that is distinct from the agent, the remitter, and the remitter's bank. The service provider can generate a deposit slip and store in a database, information about the slip. This deposit slip is marked with (a) transaction amounts for the agent's customers, (b) the bulk cash to be deposited; and (c) a summary of any discrepancy between the two. The provider makes available to the financial institution at least some of the transaction information including (a) its correlation to the deposit slip, and (b) detail greater than that produced on the deposit slip.
Owner:DEPOSITSLIPS
Peptidic protein kinase c inhibitors and uses thereof
InactiveUS20190337982A1Good curative effectEnhance immune responsePolypeptide with localisation/targeting motifOrganic active ingredientsCancer preventionVaccination
The present invention relates to novel peptides, compositions and uses thereof useful in tissue permeabilization, in particular in the context of treatment of cancer prevention and / or treatment or induction of an immune response, in particular via mucosal vaccination or anti-opioid treatment.
Owner:UNIVERSITY OF GENEVA
Adsorbent for exhaust gas
InactiveUS20090197761A1Reduce capacityAbility to efficientlyGas treatmentMolecular sieve catalystsIon exchangeMordenite
An adsorbent for exhaust gas in accordance with the present invention is produced by mixing a base material with an additive, in which the base material containing Fe-ZSM-5 is obtained by Fe ion exchange of ZSM-5 having an Si / Al2O3 molar ratio of 28 (the number of moles of Si:the number of moles of Al2O3=28:1), and in which the additive contains at least one selected from Y-zeolite having an Si / Al2O3 molar ratio of 250, mordenite having an Si / Al2O3 molar ratio of 200, and β-zeolite having an Si / Al2O3 molar ratio of 400. The adsorbent can adsorb both hydrocarbons and nitrogen oxides simultaneously effectively.
Owner:TOYOTA JIDOSHA KK
Peptidic protein kinase c inhibitors and uses thereof
PendingUS20210253635A1Prolong progression-free survivalEnhance anti-cancer efficacyPolypeptide with localisation/targeting motifOrganic active ingredientsCancer preventionOpioidergic
The present invention relates to novel peptides, compositions and uses thereof useful in tissue permeabilization, in particular in the context of treatment of cancer prevention and / or treatment or induction of an immune response, in particular via mucosal vaccination or anti-opioid treatment.
Owner:UNIVERSITY OF GENEVA
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