The invention provides a system for screening diabetic retinopathy. The system comprises an eyeground image obtaining device, an image processing and screening device and a report output device, wherein the eyeground image obtaining device is used for acquiring or receiving eyeground images of detected personnel; the image processing and screening device is used for processing the eyeground images and detecting whether pathology exists and then transmitting a detection result to the report output device; and the report output device outputs a corresponding detection report on the basis of the detection result. According to the system, the sensitivity of determining the diabetic retinopathy can reach 93.8%, the specificity can reach 94.5%, the precision is equivalent to manual determination precision, yet the detection time is greatly reduced, and the average detection time is 8.7 seconds, which is only one thirtieth of manual film reading time. Therefore, the scanning cost of the diabetic retinopathy can be substantially decreased, the diabetic retinopathy can be found early and treated early, the pain of patients is greatly reduced, and the clinical application prospect and the social benefits are quite good.