39 results about "Weight-loss drugs" patented technology

The invention discloses an inhibitor of fatty acid synthase and application thereof, comprising the following active ingredients: 5 galloyl group gluconic acid, methyl gallate and quercetin-3-O-L-rhamnoside. The mass of three active ingredients in per gram of the inhibitor of fatty acid synthase are sequentially as follows: 18-20mug, 2-3mug, 1-2mug. The inhibitor of fatty acid synthase not only can be applied to preparation of weight loss drugs, preparation of anti-cancer drugs, but also can be widely applied to additives for foods, health products, as well as daily chemicals.

An external weight-loss medicine for regulating endocrine, relates to a traditional Chinese medicine preparation, and mainly solves the problem of obesity. It is characterized in that it is composed of the following raw materials by weight: rice shell 8-12, ebony plum 12-15, rhubarb 8-12, Schisandra chinensis 9-12, ginger 8-12, Atractylodes macrocephala 9-12, white peony 16-20, raw Astragalus 28-32, Borneol 9-12, Magnolia officinalis 10-14, Psoralen 28-32, Glauber’s salt 8-12, crush the above-mentioned medicines through a 150-200 mesh sieve, mix them into a paste with sesame oil and honey , The ratio of sesame oil to honey is 1:3. Apply it on the navel and go through this acupoint to reach the various meridians of the body, adjust the balance of human endocrine, eliminate the subcutaneous skin stagnation, and convert it into heat sweat or liquid urine to be excreted, so as to achieve the purpose of weight loss. After clinical verification of 300 obese people, the average monthly loss is about 3-6 kg. Suitable for all kinds of obesity.

The invention relates to a combined formula and eating method of a three-day food changing and body shaping product, wherein the combined formula and its daily consumption are 80 parts by weight of plant-fermented lemon meal replacement powder, 40 parts by weight of plant-fermented blueberry meal replacement powder, and compound enzyme powder 10 parts by weight and predetermined volume of ginseng plant fermented beverage. The product of the invention adopts natural food ingredients, does not eat weight loss medicines, does not contain traditional Chinese medicine ingredients, and is a safe, healthy and effective weight loss and body shaping product. According to the method of the present invention, 130 trial subjects carried out a three-day food exchange, and 126 data were recovered. All trial subjects obtained satisfactory weight loss effects without any side effects.

The invention discloses a method for preparing a weight-reducing medicine orlistat. The method comprises the following steps of using lipstatin as a starting raw material, and under the catalysis of pentacarbonyl iron, making the lipstatin generate reduction reaction with a hydrazine hydrate to obtain the orlistat. The method for preparing the orlistat, which is provided by the invention, is mild in reaction condition and simple to operate; the reaction yield is effectively improved; the hydrazine hydrate is adopted as a reducing agent and a hydrogen source; reaction by-products are few; the after treatment is simple.

The invention discloses a weight losing medicament which comprises phenformin in a pharmaceutical salt form, orlistat and bisacodyl, wherein an effective dosage range of the phenformin is 20mg to 200mg per day; an effective dosage range of the orlistat is 20mg to 1500mg per day; an effective dosage range of the bisacodyl is 5mg to 15mg per day. The weight losing medicament is prepared by the following steps: mixing various components uniformly, and preparing one or several dosage forms in tablets, capsules and oral liquid mixtures to be taken or sequentially taken. Due to the phenformin, orlistat, bisacodyl and medicinal carriers, the weight losing medicament has the effects of inhibiting absorption of the intestinal tract on glucose and fat in foods, reducing blood fat, accelerating metabolism of muscles, fat and other peripheral tissues on the glucose, enhancing reflective peristalsis of rectum to accelerate excrement elimination and shortening the absorption time of the intestinal tract on sugar and fat; abdominal distension, stomachache, diarrhea and other combined effect mechanisms caused by bacteria glycolysis aerogenesis increase because the residence time of sugar and fat which are not absorbed by orlistat in the intestinal tract is extremely long are avoided, so that an aim of losing weight is achieved.

The invention relates to the field of medicines related to diabetes and obesity, and in particular to GLP-1R / GCGR dual agonist related to glucagon (Glu), a preparation method of the GLP-1R / GCGR dual agonist, a medicinal composition with the compound as an active component, and application of the GLP-1R / GCGR dual agonist and the medicinal composition in preparation of medicines for treating diabetes and obesity.