The invention discloses a multi-return-period tsunami disaster evaluation method based on Monte Carlo stochastic simulation. The method comprises: S1, applying multiple source parameter estimation methods to establish a seismic activity parameter logic tree of potential tsunami source areas; S2, applying linear tsunami numerical simulation to establish a tsunami unit source Green's-function library; S3, applying a Monte Carlo stochastic simulation to generate a stochastic seismic event set according to the above logic tree; S4, applying stochastic slippage simulation to generate a tsunami waveamplitude set according to the tsunami unit source Green's-function library and a stochastic seismic event set; and S5, carrying out counting and uncertainty analysis on multi-return-period tsunami disaster distribution results according to the tsunami wave amplitude set. According to the above method, problems that in the prior art, risk evaluation results are higher, and corresponding occurrence probability thereof cannot be given can be solved, multiple types of uncertainty are fused into a final evaluation result, credibility of the result is increased, running efficiency is improved at the same time, and targeted disaster prevention and mitigation deployment and urban construction planning of decision makers are facilitated.