80 results about "Severe burn" patented technology

The present invention relates to a dermal substitute comprising the biodegradable polymer such as collagen and the biomaterial such as amnion, the preparation method and the use thereof. Specifically, the present invention provides with an amnion-collagen sponge complex structure prepared by attaching, inserting or incorporating an amnion obtained from placenta to / in collagen. Inventive dermal substitute can be applied to surgery and wound requiring skin graft, for example, severe burns such as second-degree burn, without rejection by immune system. Further, inventive dermal substitute with amnion instead of silicone membrane has several advantages, such as better biocompatibility, anti-inflammatory activity and promoting activity of wound healing and commercial utilization as basement membrane. Also, inventive complex structure can be used as the basic matrix of bio-artificial skin for culturing cells and the biodegradable basic matrix for preparing artificial organs.

The invention discloses a multi-life monitoring system based on FMCW (frequency modulated continuous wave) wideband radar. The multi-life monitoring system comprises a transmitting unit, a receiving unit, a signal processing unit and a wireless signal transmitting unit; an FMCW signal is transmitted from the FMCW wideband radar to no less than one human object by virtue of the transmitting unit; a reflected echo signal is received by virtue of the receiving unit; the echo signal, which carries vital sign signals, is processed by virtue of the signal processing unit; the vital sign signals are demodulated and separated from the echo signal; and the vital sign signals are transmitted to a computer terminal by virtue of the wireless signal transmitting unit, so that respiration and heartbeat signals of detected persons are monitored under the condition of avoiding contact with the bodies of the detected persons. With the implementation of the multi-life monitoring system disclosed by the invention, under the circumstance of avoiding the contact of any electrodes and sensors with patients, the respiration and heart rates of the plurality of patients can be simultaneously monitored by a long time at a relatively long distance, so that the detected persons can feel more easily and comfortably; the multi-life monitoring system can be widely applied to clinical dynamic monitoring and sleep quality monitoring of patients with severe burn and the like; and meanwhile, the multi-life monitoring system can be also applied to researches in the field of psychology.

The present disclosure relates to a method for treating severe burns using a preparation of tissue-derived material, which may comprise stem cells. The method may include systemic administration of stem cells. The method may also include administration of topical preparations of stem cells or tissue extract.

The invention relates to a method for smelting an iron-based nanocrystalline master alloy. The method comprises the following process steps of: putting raw materials in a furnace according to the process requirement; vacuumizing, transmitting power, adjusting heating power and time as well as adding residual pure iron into the furnace in the process; insulating for 15 minutes when the temperature reaches at 1520+ / -10 DEG C, stopping power transmission and cooling to 1460 + / -10 DEG C, adding metallic silicon, adjusting the heating power to 100kW, smelting for 30 seconds, adding cathode copper into the furnace after the time is ended and guaranteeing the heating power of 100kW and the smelting time for 30 seconds at the same time; and stopping power transmission and cooling to 1360+ / -10 DEG C, opening a furnace cover, continuously to heat to 1280+ / -10 DEG C, tapping steel and pouring molten steel into a steel ingot mould. Through the reasonable material distribution and the control of heating power and time, the smelting efficiency is improved and the problems of great furnace lining damage, severe burning loss of beneficial elements, high impurity content in the master alloy and the like in the process of smelting nanocrystalline master alloy are effectively solved.

The invention discloses a comprehensive burn treatment bed which is novel in structure, convenient and safe to use and capable of conducting automatic operation, reducing treatment time, improving treatment effects and reducing working intensity and is driven by a machine. The bed comprises a bed body, a lifting mechanism, a rotating mechanism, an electric device and an immersion bath. A body turning bed and a body turning frame are arranged and matched in use, a patient lies flatly when the bed is turned upwards, transposition is conducted when the bed is turned downwards, irradiation treatment is conducted on the patient on the body turning frame, and pains of the patient caused by the fact that the patient is bound and hung for back irradiation are removed. An automatic location fixed separation moving device is arranged to replace manual transportation of the body turning frame, an infrared electric heater case all-dimensional radiation effect is achieved in use, the immersion bath is added clinically, and ventilation suspension is conducted on the patient on time to prevent pressure sores. A worm reducer and a bedside guardrail are provided to ensure clinical safety of the patient. The treatment bed is clinically applied to moderate and severe burn patients.

The present disclosure relates to, inter alia, antibodies, or antigen-binding fragments thereof, that bind to C5a and to use of the antibodies in methods for treating or preventing complement-associated disorders such as, but not limited to, atypical hemolytic uremic syndrome, age-related macular degeneration, rheumatoid arthritis, sepsis, severe burn, antiphospho lipid syndrome, asthma, lupus nephritis, Goodpasture's syndrome, and chronic obstructive pulmonary disease.

The invention discloses a medicine for treating burn and scald, which is prepared from proper amount of prepared coptis root, black sanguisorba root, folium ilicis chinensis, beautyberry, angelica dahurica, plaster of pairs, borneol and benne oil. The medicine has obvious effect on treating burn and scald, particularly two-degree or three-degree severe burn and scald, ensures that the burn-scald skin can rapidly recover with no scar left after healing, is convenient to use, has no any side effect, but has the effective rate of 100 percent and the cure rate of 99 percent. The medicine is easy to prepare and is ideal for treating the burn and the scald.

A compound of formula (I) or a salt thereof are provided:wherein R1, X and R3 are defined in the specification, useful in the treatment of disorders mediated by KMO such as acute pancreatitis, chronic kidney disease, other conditions associated with systemic inflammatory response syndrome (SIRS), Huntington's disease, Alzheimer's disease, spinocerebellar ataxias, Parkinson's disease, AIDS-dementia complex, amylotrophic lateral sclerosis (ALS), depression, schizophrenia, sepsis, cardiovascular shock, severe trauma, acute lung injury, acute respiratory distress syndrome, acute cholecystitis, severe burns, pneumonia, extensive surgical procedures, ischemic bowel, severe acute hepatic disease, severe acute hepatic encephalopathy or acute renal failure.

The invention discloses a cancer inhibition and flesh engendering medicine for treating burns, scalds, the internal and external ulcer and the cataract, and its preparation method, and relates to the medical field. The medicine is prepared from the following raw materials, by weight, 25-30 parts of dahurian angelica root, 15-30 parts of Lithospermum erythrorhizon, 15-25 parts of camphor, 10-15 parts of borneol, 25-40 parts of Radix Sanguisorbae, 10-35 parts of ocean nitrate, 12-30 parts of Cattail Pollen, 10-42 parts of Nodus Nelumbinis Rhizomatis, 10-45 parts of charred Chinese Arborvitae Twig, 10-40 parts of Crinis Carbonisatus, 12-45 parts of Copperleaf herb, 10-35 parts of Bletilla striata, 10-30 parts of Cogongrass rhizome, 10-30 parts of Yerbadetajo Herb, 10-40 parts of Agrimonia eupatoria, 10-40 parts of Japanese Thistle Herb, 10-40 parts of Herba Cirsii, 10-35 parts of Rubia cordifolia, 10-40 parts of Monochoria vaginalis Presl, 1-10 parts of Herba Taraxaci, 10-40 parts of Ottelia alismoides, 10-25 parts of Spora Lygodii, 1-30 parts of Herba Violae and 1-30 parts of honeysuckle flower. The medicine has the advantages of anti-inflammation, pain relieving, flesh engendering without scars, bleeding stopping, restoration, fire purging, detoxification, phlegm reduction and vein relaxing, can treat severe burns and scalds, the cataract and diabetes, and inhibit the esophagus cancer and the stomach cancer.

Described herein are conjugates of collagen peptides and metal binding agents and compositions resulting therefrom, useful in various tissue engineering and regeneration applications, in cell culture, cell adhesion, cosmetic surgery, construction of artificial skin substitutes, management of severe burns and burn surgery, reconstruction of bone and a wide variety of dental, orthopedic and surgical purposes, as drug delivery vehicles and in delivering populations of cells to a site of disease or injury.

The present invention discloses a lightning-caused breakage preventing method for an insulated overhead line, comprising the steps of: stripping and cutting an insulated conductor at the position of an insulator to obtain a section of bare section; parallelly and fixedly arranging a bare conductor of which the length is greater than the length of the bare section to the insulated conductor at the position of the insulator, wherein one end of the bare conductor is bound and fixedly connected with the bare section; and performing sealing for the connecting position between the bare conductor and the bare section. According to the lightning-caused breakage preventing method, one section of the bare conductor is installed on the insulated conductor, one end of the bare conductor is bound and fixedly connected with a metal wire in the insulated conductor, then sealing is performed, when a direct lightning or lightning induced voltage acts on the bare conductor to cause an insulator arc-over, continuous power-frequency short-circuit current arcs move along the axial direction of the bare conductor under the effect of electrodynamic force, thereby greatly reducing the probability of severe burn of the insulated conductor, and greatly reducing the cost, in addition, a simple structure and convenient operation are achieved, and operating efficiency is improved.

The invention relates to a medicine composition for treating burn and scald, a method for preparing the medicine composition and application thereof. The medicine composition mainly comprises, by weight, 10-30 parts of radix rubiae, 7-17 parts of cortex phellodendri, 20-40 parts of radix scutellariae, 50-80 parts of radix angelicae sinensis, 20-40 parts of radix angelicae dahuricae, 10-30 parts of rhizoma polygoni cuspidate, 7-17 parts of myrrh, 30-50 parts of radix arnebiae seu lithospermi, 20-40 parts of radix glycyrrhizae, 10-30 parts of borneolum syntheticum, 35-65 parts of radix et rhizoma rhei, 10-30 parts of radix astragali, 10-30 parts of flos carthami and 30-60 parts of beeswax. The medicine composition, the method and the application have the advantages that the medicine composition has functions of cooling blood to stop bleeding, relieving swelling and pain, purging fire, removing toxic substances, removing necrotic tissues and promoting tissue regeneration, the micro-circulation capacity and the healing ability of wounded tissues can be improved, the medicine composition is extremely high in anti-infection capacity, and miraculous effects can be clinically realized for slight, moderate and severe burn and scald and different types of wound infection; the method is easy to implement, and effective components in raw materials can be reserved to the greatest extent; patients can conveniently smear and use the ointment medicine composition, and the medicine composition can directly act on burn sites of the patients, can become effective fast and is convenient to use.

Compounds of formula (I)wherein:R1 is heteroaryl optionally substituted by methyl, ethyl, halo or ═O; andR2 is H, methyl or ethyl.and salts thereof are KMO inhibitors and may be useful in the treatment of various disorders, for example acute pancreatitis, chronic kidney disease, other conditions associated with systemic inflammatory response syndrome (SIRS), Huntington's disease, Alzheimer's disease, spinocerebellar ataxias, Parkinson's disease, AIDS-dementia complex, HIV infection, amylotrophic lateral sclerosis (ALS), depression, schizophrenia, sepsis, cardiovascular shock, severe trauma, acute lung injury, acute respiratory distress syndrome, acute cholecystitis, severe burns, pneumonia, extensive surgical procedures, ischemic bowel disease, severe acute hepatic disease, severe acute hepatic encephalopathy or acute renal failure.

The invention discloses a medical wound treatment bed with reasonable structure, convenient use, comfort, safety, economy and multifunctional structure, which comprises a bed body, a steel wire bed, a lifting mechanism, an electrical device, and a transposition device. The bed body is assembled and welded by the front and rear headboards and longitudinal stainless steel pipes. The bed frame and the front and rear headboards are plugged in, and the steel wire bed is set in the bed frame. The first and second guide shafts of the bed frame are connected to the bed frame respectively. The first and second conduits on the top are slidingly assembled, the bottom of the bed frame is equipped with a worm gear reducer, and the gear on it drives the rack to lift the steel wire bed. An infrared electric heating box is installed on the longitudinal tube, and travel switches are installed on the top and bottom of the steel wire bed. The electric control panel is equipped with a lifting and infrared electric heating control circuit to form a system circuit. The above functional structure can perform regular air ventilation for long-term bedridden patients to prevent and treat pressure sores, and implement infrared radiation therapy for moderately and severely burned patients. The invention is applicable to the clinical application of patients with long-term bed rest, burns and some skin diseases.

The invention discloses a fuel injector for a free piston type engine. The fuel injector comprises a hydraulic pump body assembly, a first air cylinder assembly and a second air cylinder assembly, wherein a first air inlet, a first exhaust opening and a first fuel injection port close to the first air inlet are formed in the extending surface on the cylinder wall of the first air cylinder assembly; a first spray nozzle of the first fuel injector is positioned in the first fuel injection port; a second air inlet, a second exhaust opening and a second fuel injection port close to the second air inlet are formed in the extending surface on the cylinder wall of the second air cylinder assembly; and a second spray nozzle of the second fuel injector is positioned in the second fuel injection port. The fuel injector disclosed by the invention has the benefits that a fuel injector with lower use cost can be used; the fuel is prevented from being contacted with the air cylinder wall; more-uniform mixed oil gas is ensured; the fuel injector is positioned nearby close to the air inlet, so that the fuel can be directly injected to the air cylinder; and meanwhile, the fuel injector can be allowed to leave from the burning range. Therefore, the fuel injector is prevented from being exposed in a severe burning environment.

The invention discloses a method for preparing a direct moxibustion material finished product by using a folium artemisiae argyi wet method. The problems that in the prior art, moxa cones are manuallymanufactured, and severe burning pain and wounds are generated by applying a traditional moxibustion therapy are solved. The method is characterized in that fresh folium artemisiae argyi, dry foliumartemisiae argyi or aged folium artemisiae argyi can be used as a raw material; a wet process flow is adopted, and crushing or mashing, steaming, water milling and dehydration treatment are performedto obtain moxa mud; and then the moxa mud is subjected to strip making, wrapping, drying, shearing, packaging and other processes to obtain moxa stick and moxa cone series finished products suitable for medical direct moxibustion. The method has the advantages of being reasonable in process, easy to manufacture, novel in application, low in cost and the like; the history of manual manufacturing ofthe moxa cone is ended through series construction of finished products, the application standard is unified, the blank of direct moxibustion applying material finished products in China is filled up, the ideal effect of doctors and patients is achieved through application, and the application prospect is very wide.

The invention relates to a labyrinth oil-gas separation device for an engine cylinder head cover, which comprises a coaming plate arranged on the cylinder head cover, a transverse partition and a longitudinal septum connected with it are arranged on the inner side of the coaming plate, and on the coaming plate A waist partition is also provided, and a waist partition guide plate is obliquely arranged at the end of the waist partition, and the above partitions are fixed together with the cylinder head cover body. The invention has reasonable structure and ingenious design, which can not only make the oil and gas separation more thorough, reduce the original serious failure of burning engine oil, but also reduce the consumption of engine oil, improve the performance of the engine, improve the emission performance, reduce pollution, and be more beneficial environmental protection.

The invention discloses a traditional Chinese medicine spray for treating severe burn and a preparation method thereof and belongs to the field of traditional Chinese medicines. The effective components of the traditional Chinese medicine spray are prepared from the following raw materials: marsh marigold, folium eucalypti, shrubby breynia, melangolo, cottonrose hibiscus, pear pericarp, ormosia henryi, eriolaena spectabilis, pyrrosia calvata, aloe leaves, hawthorn, birch barks, garden eggplant flowers, aralia fargesii, jasmine and lithospermum. The medicines selected by the traditional Chinese medicine spray disclosed by the invention are compatible and appropriate, so that the traditional Chinese medicine spray meets the theories of traditional Chinese medicines and modern medicine and pharmacology, further has the functions of clearing away heat and toxic materials, resisting bacteria and diminishing inflammation and eliminating swelling and relieving pains, has a unique curative effect to severe burn, can repair the damaged tissues of skins and promote cell functional recovery, effectively inhibits pains caused by skin burn, and is convenient to use, scar-free after use, low in cost, safe and reliable, free from toxic and side effect and worth of widely popularizing and applying clinically.

The present invention relates to an antipyrotic having compositions excellent for treating burn and a normally used carrier in a fixed ratio, and a method of manufacturing the same. The antipyrotic of the present invention has, as its main composition, a carbonized pine cone that is yielded by completely combusting selected pine cones put in a sealed container after washing and drying at a temperature of 100 to 300° C. and has, as an additive, a normally used carrier. As described in detail, the present invention provides provide a cream or ointment type of antipyrotic that can easily treat with excellent treating power serious burn more than the second degree burn as well as slight burn that does not require special treatment by medical specialist. Their treatment ability is excellent and they can shorten the treatment period considerably and leave almost no scars on the skin after complete healing. They are made of plant formulations and thus show almost no side effects to the human body. In the prior treatment of using gauze, the patients complain about pain caused as the gauze and the scab are exfoliated together, when the gauze is removed from the affected region after a certain period. However, the antipyrotic of the present invention can be applied to the affected region softly without causing pains and thus are convenient to use.

The invention discloses a traditional Chinese medicine paste for treating severe burn and a preparation method thereof. The traditional Chinese medicine paste consists of the following raw material medicines in parts by weight: 100-200 parts of garden balsam, 100-200 parts of burdock root, 15-30 parts of rhizoma polygoni cuspidati, 10-20 parts of cacumen platycladi, 5-10 parts of radix sanguisorbae, 1-5 parts of rhizoma coptidis, 5-10 parts of orostachys fimbriatus, 1-5 parts of crinis carbonisatus, 10-20 parts of yellow wax, 1-10 parts of white wax, 1-5 parts of pearl powder, 1-5 parts of dried alum, 5-10 parts of styrax, 1-5 parts of borneol and 400-800 parts of sesame oil. The traditional Chinese medicine paste disclosed by the invention takes effect quickly, realizes good curative effect and high cure rate and brings little pain to the patients when treating severe burn. The traditional Chinese medicine paste and the preparation method thereof deserve popularization.

The invention provides a burn and scald recovery application. The burn and scald recovery application consists of the following materials in parts by weight: 5 to 8 parts of pseudo-ginseng, 3 to 5 parts of burnet, 10 to 15 parts of garcinia multiflora, 5 to 8 parts of radix scutellariae, 5 to 10 parts of honeysuckle, 5 to 10 parts of purple gromwell, 5 to 8 parts of Chinese lobelia, 3 to 5 parts of mint, 13 to 15 parts of angelica dahurica, 5 to 10 parts of red sage root, 5 to 8 parts of canella, 5 to 8 parts of sapanwood, 13 to 15 parts of radix ampelopsis, 5 to 8 parts of myrrh, 5 to 8 parts of peal powder, 3 to 5 parts of honey and 6 to 11 parts of wormwood. Besides conventional anti-inflammatory and pain-killing, swelling-dispersing and pus-repelling and blood circulation-promoting and blood stasis-removing effects, the burn and scald recovery application also has the effects of regenerating tissues to heal wounds and fading scars, so that a scar which is left after a burn or a scald heals can be faded, and the burn and scald recovery application also has a good effect even for patients with severe burns and scalds. Thus the burn and scald recovery application provided by the invention can solve the problem that the scar-fading effect of Chinese and western medicines in the prior art is proor.

The invention features methods, devices, pharmaceutical compositions, and kits for treating or preventing acute vascular leak. Such methods may involve contacting an effective amount of bosutinib for treating or preventing acute vascular leak with a subject in need thereof. Conditions associated with acute vascular leak include ischemic brain injury, stroke, septic shock, anthrax lethal toxin, anaphylaxis, trauma, severe episodic vasculitis, acute lung injury, ventilator-induced lung injury, transfusion-related acute lung injury, acute respiratory distress syndrome, severe burn injury, circulatory shock, capillary leak syndrome, and ischemia-reperfusion injury. The invention also features automatic injection devices, resuscitation fluids, or pharmaceutical compositions comprising an effective amount of bosutinib for treating or preventing acute vascular leak. The invention further features kits for use in the methods of the invention.

The invention discloses a skin scar repairing cream. The skin scar repairing cream is prepared from, by weight, 13-15% of borneol, 11-12% of sanguis draxonis, 15-16% of beeswax, 13-18% of radix et rhizoma rhei, 15-17% of emilia sonchifolia, 11-12% of crocus sativus, 13-15% of aloe and 2-3% of sesame oil. The skin scar repairing cream has the effects of relieving swelling and promoting tissue regeneration, astringing dampness and furuncle, promoting granulation and healing wound and resisting bacteria and diminishing inflammation, has a miraculous effect especially for severe burns, and can effectively protect wounds from infection and promote rapid healing of the wounds, so that burned skin can quickly restore functions. The skin scar repairing cream has the advantages of being free of anyside effect, safe, reliable, quick in effect and convenient to carry and does not generate scars after healing.

The invention provides an externally-applied traditional Chinese medicine composition for treating burns and scalds, which is prepared from the following preferred traditional Chinese medicinal materials in parts by weight: 20 parts of calcite, 20 parts of red halloysite, 15 parts of rhubarb, 15 parts of borneol, 15 parts of baikal skullcap root, 20 parts of elephant hide, 20 parts of talcum and 20 parts of frankincense. The traditional Chinese medicinal materials are cleaned, disinfected, baked and crushed into powder with 80-150 meshes, the powder is mixed uniformly in parts by weight, and then, the mixture is weighed and bottled or bagged or boxed to obtain a finished product; and during treating, the finished product is blended with sesame oil to obtain ointment so as to be smeared on the wounds of burns and scalds. The externally-applied traditional Chinese medicine composition has good effects on relieving pain, resisting infection, eliminating pus, preventing scars and shortening courses of treatment, and has the effects of removing pathogenic heat from blood, alleviating pain and eliminating swelling, promoting blood circulation to remove blood stasis, eliminating swelling and promoting wound healing, removing slough and promoting growth of tissue regeneration as well as diminishing inflammation and removing scars. By using the externally-applied traditional Chinese medicine composition for treating hundreds of patients with slight and severe burns and scalds, good cure effects are achieved.

The invention discloses an application of an SIRT1 (silent information regulator 1), and in particular an application of an SIRT1 in preparation of medicines for treating severe burns or wounds. The SIRT1 can be used for reducing the mortality of severely burned rats, obviously improving the survival conditions of the early severely burned rats as well as reducing the apoptosis of tissue cells of multiple organs (heart, lungs, kidneys and the like), plays an important role in treating severe burns or wounds, and has wide application prospects.

The invention discloses a traditional Chinese medicine for treating burn and scald. The traditional Chinese medicine is prepared from the following medical materials in parts by weight: 10-15 parts of garden burnet, 5-8 parts of rhizoma coptidis, 15-20 parts of scutellaria baicalensis, 10-15 parts of climbing groundsel herb and 80-100 parts of drinking water. A preparation method of the traditional Chinese medicine comprises the following steps: putting the medical materials in a medicine decocting appliance, adding the domestic drinking water, decocting for 15-20 minutes, cooling to be tepid, removing dregs, and sealing for sterile preserving. The prepared traditional Chinese medicine is put in a sprayer to be sprayed 3 times a day and 3 times every time. A course of treatment of the traditional Chinese medicine lasts 15 days, slight burn and scald can be healed after one course of treatment, and severe burn and scald need two or three courses of treatment. Hundreds of patients have been successfully healed, the effective rate is 82 percent, and the recovery rate is 75 percent.

The invention provides a traditional Chinese medicine composition for treating burns and scalds, a traditional Chinese medicine preparation and a preparation method thereof, which belong to the technical field of a traditional Chinese medicine composition. The traditional Chinese medicine composition includes the following components in parts by weight: 1 to 100 parts of garden burnet, 1 to 100 parts of rheum officinale, 10 to 200 parts of gypsum rubrum, 1 to 100 parts of scutellaria baicalensis, 1 to 50 parts of chuanlian, 1 to 100 parts of Calomelas, and 0.3125 to 3.125 parts of borneol. Thetraditional Chinese medicine preparation provided by the present invention uses the sesame oil to adjust the traditional Chinese medicine composition into a paste, and the current preparation is directly applied to the wound, which is convenient to use and has a good therapeutic effect; severe burns can be cured in 15 days, moderate burns can be cured in 7 days, and mild burns can be cured in 2 days.