57 results about "Piperazine salt" patented technology

Disclosed is a flame retardant composition which comprises: a flame retardant composition comprising 1 to 99 parts by mass of a salt of piperazine with an inorganic phosphorus compound selected from piperazine phosphate, piperazine pyrophosphate, piperazine polyphosphate and a mixture of two or more of these piperazine salts (component (A)), and 99 to 1 part by mass of a salt of melamine with an inorganic phosphorus compound selected from melamine phosphate, melamine pyrophosphate, melamine polyphosphate and a mixture of two or more of these melamine salts (component (B)) (provided that the total amount of the components (A) and (B) is 100 parts by mass); 0.01 to 10 parts by mass of a silicone oil (component (C)); and 0.01 to 20 parts by mass of a monoester compound (component (D)) produced by reacting a monoamide compound of a higher aliphatic carboxylic acid and / or a higher aliphatic carboxylic acid with a univalent to trivalent alcoholic compound.

A flame retardant composition contains, with respect to a flame retardant composition containing 1 to 99 parts by mass of a salt of piperazine and an inorganic phosphorus compound (component (A)) selected from piperazine phosphate, piperazine pyrophosphate, piperazine polyphosphate, or a mixture of at least two of the piperazine salts, and 99 to 1 parts by mass of a salt of melamine and an inorganic phosphorus compound (component (B)) selected from melamine phosphate, melamine pyrophosphate, melamine polyphosphate, or a mixture of at least two of the melamine salts (wherein the total of the component (A) and the component (B) is 100 parts by mass): 0.01 to 10 parts by mass of silicone oil; and 0.01 to 20 parts by mass of a monoamide compound of a higher aliphatic carboxylic acid and / or a monoester compound produced by reacting a higher aliphatic carboxylic acid with a monovalent to trivalent alcohol compound.

The invention provides a flame retardant composition comprising 1-99 weight parts of a salt of piperazine and an inorganic compound selected from among piperazine phosphate, piperazine pyrophosphate and piperazine polyphosphate, or a mixture of two or more of these piperazine salts (ingredient (A)), 99-1 weight parts of a salt of melamine and an inorganic compound selected from among melamine phosphate, melamine pyrophosphate and melamine polyphosphate, or a mixture of two or more of these melamine salts (ingredient (B)) (wherein, the sum of ingredient (A) and ingredient (B) is 100 weight parts), 0-50 weight parts of an arbitrary ingredient (ingredient (C)), and 0.01-20 weight parts of a silicone oil having a viscosity at 25° C. of 5000 mm2 / s (ingredient (D)) which is added thereto. This flame retardant not only has superior flame retarding properties, but also has enhanced powder properties and anti-hygroscopic properties, and when it is added to a resin, there is little change of electrical resistance.

The invention provides a flame retardant composition comprising 1-99 weight parts of a salt of piperazine and an inorganic compound selected from among piperazine phosphate, piperazine pyrophosphate and piperazine polyphosphate, or a mixture of two or more of these piperazine salts (ingredient (A)), 99-1 weight parts of a salt of melamine and an inorganic compound selected from among melamine phosphate, melamine pyrophosphate and melamine polyphosphate, or a mixture of two or more of these melamine salts (ingredient (B)) (wherein, the sum of ingredient (A) and ingredient (B) is 100 weight parts), 0-50 weight parts of an arbitrary ingredient (ingredient (C)), and 0.01-20 weight parts of a silicone oil having a viscosity at 25 DEG C of 5000mm 2 / s (ingredient (D)) which is added thereto. This flame retardant not only has superior flame retarding properties, but also has enhanced powder properties and anti-hygroscopic properties, and when it is added to a resin, there is little change of electrical resistance.

The present invention provides a flame-retardant composition having excellent heat resistance and reduced risk of corroding processing equipment during resin compounding, specifically a flame-retardant composition containing 20-50 parts by mass of component (A), 50-80 parts by mass of component (B) (where the total of component (A) and component (B) is 100 parts by mass), and 0.01-5 parts by mass of component (C). Component (A): one or more melamine salts selected from melamine orthophosphate, melamine pyrophosphate, melamine polyphosphate, and mixtures containing two or more of these melamine salts. Component (B): one or more piperazine salts selected from piperazine orthophosphate, piperazine pyrophosphate, piperazine polyphosphate, and mixtures containing two or more of these piperazine salts. Component (C): hydrotalcite compound.

A series of monoquarternary piperazium salts including a structure of a formula I or II are provided. In formula I or II, R1, Ra, and RX are as defined in the specification. The monoquarternary piperazium salt of KMUP or piperazine disclosed in the present invention is characterized by being presented in a pro-drug form and having various pharmaceutical functions.

Disclosed is a flame retardant composition having excellent flame retardancy and processability, providing a flame-retardant synthetic resin composition including this flame retardant composition and having excellent flame retardancy and processability. Specifically, the following components are used in combination: as component (A), 20 to 50 parts by mass of at least one type of melamine salt selected from the group consisting of melamine orthophosphate, melamine pyrophosphate, and melamine polyphosphate; as component (B), 50 to 80 parts by mass of at least one type of piperazine salt selected from the group consisting of piperazine orthophosphate, piperazine pyrophosphate, and piperazine polyphosphate (the total of component (A) and component (B) is 100 parts by mass); and as component (C), 0.01 to 20.0 parts by mass of a bicyclophosphoric ester compound represented by the following general formula (1). The details of formula (1) are as described in the Description.

This flame-retardant polypropylene composition contains a random copolymer polypropylene as a synthetic resin component and contains the following component (A) and component (B) as flame-retardant components. Said composition preferably also contains component (C), zinc oxide, as a flame-retardant component. A styrene-based thermoplastic elastomer is also preferably contained as a synthetic resin component. Component (A): one or more melamine salts selected from the group consisting of melamine orthophosphate, melamine pyrophosphate, and melamine polyphosphate. Component (B): one or more piperazine salts selected from the group consisting of piperazine orthophosphate, piperazine pyrophosphate, and piperazine polyphosphate

The invention provides a flame retardant composition containing: component (A), which is 20-50 parts by mass of one or more melamine salts selected from the group of melamine orthophosphate, melamine pyrophosphate, and melamine polyphosphate; component (B), which is 50-80 parts by mass of one or more piperazine salts selected from the group of piperazine orthophosphate, piperazine pyrophosphate, and piperazine polyphosphate (where the total of component (A) and component (B) is 100 parts by mass); component (C), which is 0.01-5.0 parts by mass of a silane coupling agent; and component (D), which is 0.01-1.0 part by mass of an aliphatic dicarboxylic acid ether ester compound represented by general formula (1). Formula (1) is described in detail in the specification.

The present invention relates to novel monohydrochloride, dihydrochloride, monohydrobromide, maleate and methanesulphonate salts of trans 4-(2-(4-(2,3-dichlorophenyl)-piperazine-1-yl)-ethyl)-N,N-dimethylcarbamoyl-cyclohexylamine and / or their hydrates and / or solvates. Moreover, the invention relates to the process for preparing the salts and their hydrates and / or solvates, to their use in the treatment and / or prevention of conditions which require modulation of dopamine receptor and to pharmaceutical compositions containing them.

A composition according to the present invention contains component (A), component (B), and component (C) below, wherein component (A)is at least one melamine salt selected from the group consisting of melamine orthophosphate, melamine pyrophosphate, and melamine polyphosphate; component (B)is at least one piperazine salt selected from the group consisting of piperazine orthophosphate, piperazinepyrophosphate, and piperazine polyphosphate; and component (C)is a monohydrate of alumina. According to the present invention, a composition is provided, which, when mixed with a resin, can impart excellent processability and moldability and flame retardancy to the resin.

The invention relates to novel trans N-{4-{2-[4-(2,3-dichlorophenyl)-piperazine-1-il]-ethyl}-cyclohexylamine dihydrochloride monohydrate and a process for the preparation of the trans N-{4-{2-[4-(2,3-dichlorophenyl)-piperazine-1-il]-ethyl}-cyclohexylamine dihydrochloride monohydrate, said process comprising the stepsa) reacting trans 2-{1-[4-(N-tert-butoxycarbonyl)amino]-cyclohexyl}-acetic acid ester with sodium borohydride and aluminum trichloride to give trans 2-{1-[4-(N-tert-butoxycarbonyl)-amino]-cyclohexyl}-ethanol;b) reacting trans 2-{1-[4-(N-tert-butoxycarbonyl)-amino]cyclohexyl}-ethanol obtained with methanesulfonic acid chloride in the presence of an acid binding agent to give trans 2-{1-[4-(N-tert-butoxycarbonyl)-amino]-cyclohexyl}-ethyl methanesulfonate;c) reacting trans 2-{1-[4-(N-tert-butoxycarbonyl)-amino]-cyclohexyl}-ethyl methanesulfonate obtained with 2,3-dichlorophenyl-piperazine in the presence of an acid binding agent to give trans 2-{1-[4-(N-tert-butoxycarbonyl)-amino]-cyclohexyl}-carbamic acid tert-butylester;d) heating trans 2-{1-[4-(N-tert-butoxycarbonyl)-amino]-cyclohexyl}-carbamic acid tert-butylester obtained to a temperature between 40-100° C. in a mixture of aqueous hydrochloric acid / methanol to give trans N-{4-{2-[4-(2,3-dichlorophenyl)piperazine-1-il]-ethyl}-cyclohexylamine dihydrochloride monohydrate.

The composition according to the present invention contains (A) an amine phosphate, and (B) melamine cyanurate. In the composition according to the present invention, the component (A) preferably contains (A-1) and (A-2). Component (A-1): at least one melamine salt selected from the group consisting of melamine orthophosphate, melamine pyrophosphate, and melamine polyphosphate. Component (A-2): atleast one piperazine salt selected from the group consisting of piperazine orthophosphate, piperazine pyrophosphate, and piperazine polyphosphate. The present invention can provide a composition which, when blended with a resin, imparts to the resin a dripping prevention effect and superior flame resistance, and can allow production of a molded article having good surface smoothness.

Disclosed are a process for preparing new crystal salt forms of sulfasalazine, in particular crystal Form A of the D(−)-N-methylglucamine (meglumine) salt of sulfasalazine (see FIG. 1), crystal form A of the piperazine salt of sulfasalazine (see FIG. 2) and crystal Form B of the diethylamine salt of sulfasalazine (see FIG. 4), and a pharmaceutical composition containing one or more of the inventive crystal salt forms in particular in the treatment of a disease or condition in which modulation of inflammatory cells is beneficial, a disease or condition concerning bones or joints and / or the gastro-intestinal tract.

A flame-retardant synthetic-resin composition which comprises 20-50 parts by mass of component (A) which is at least one melamine salt selected from the group consisting of melamine orthophosphate, melamine pyrophosphate, and melamine polyphosphate, 50-80 parts by mass of component (B) which is at least one piperazine salt selected from the group consisting of piperazine orthophosphate, piperazinepyrophosphate, and piperazine polyphosphate (the sum of component (A) and component (B) is 100 parts by mass), and 1-50 parts by mass of component (C) which is a compound represented by formula (1).(R1 represents a residue of an aliphatic monocarboxylic acid or a residue of an aromatic monocarboxylic acid.)

A composition includes first, second, and third components. The composition preferably includes 0.1 to 50 parts by mass of the third component with respect to 100 parts by mass in total of the first and second components. The first component is at least one type of melamine salt selected from the group consisting of melamine orthophosphate, melamine pyrophosphate, and melamine polyphosphate. The second component is at least one type of piperazine salt selected from the group consisting of piperazine orthophosphate, piperazine pyrophosphate, and piperazine polyphosphate. The third component is cyanuric acid or zinc cyanurate.