58 results about "Fungal skin disease" patented technology

The invention discloses a skin wound repair hydrogel and a preparation method thereof. The skin wound repair hydrogel contains aloe original gel, chitosan, beta-sodium glycerophosphate and water; pH is 7.0-7.5. The preparation method mainly comprises the following steps: mixing 1-4% (w / v) chitosan solution and aloe original gel in volume ratio of 1: 1-2 at 2-10 degrees centigrade, then dropwise adding beta-sodium glycerophosphate aqueous solution, adjusting pH of solution to 7.0-7.5, and forming the hydrogel at 4-50 degrees centigrade. The skin wound repair hydrogel provided by the invention is capable of promoting generation of skin capillarity tubes, is beneficial to growth of tissue to protect nerve endings of wounds and reduce pain, is used for treating suppurative dermatosis, superficial dermatomycosis, skin trauma and ultraviolet dermatitis, and is featured with effects of diminishing inflammation, sterilizing, alleviating pain, absorbing heat, anti-swelling, softening skins, relieving pain and improving scars.

The invention relates to a Chinese medicinal composition for treating skin diseases. The Chinese medicinal composition is prepared by stir-frying various Chinese herbal medicines such as phellodendron, baical skullcap root, manchurian wildginger, schizonepeta spike, bulbus fritilariae, golden larch bark, sulphur, realgar, toad venom, musk, mint rice, plant soot, salicylic acid and the like over slow fire, grinding accurately, mixing with badger fat, antelope oil and the like, grinding again and extracting. The Chinese medicinal composition can remove abnormal phlegmatic temperament, bile fluid and sepsis and relieve swelling and itching, and is used for treating parapsoriasis guttata (psoriasis), tinea manuum, tinea corporis, tinea pedis, tinea versicolor, intractable dermatitis, neurodermatitis, fungal skin diseases, leuconychia, purulent skin diseases, facial pityriasis, pityriasis rosea, seborrheic dermatitis, prurigo nodularis, scabies, eczema, herpes, acnes and the like.

This invention relates to the field of medical preparations, revealing a Lyrate nightshade gelatin and its preparation method and use. Performance and quality of the gelatin processed by the method of this invention is table. Compared with the common used external applied soft creams, the lyrate nightshade gelatin has many strong points: easy outspreading of its coated cloth, easy absorbed, fast action, without greasiness. Animal test results indicate that the gelatin can be used effectively to treat eczema and fungal skin disease. Toxin tests show that the gelatin is clinically safe. It can be safely and effectively externally used to treat chromic moist symptom, dermatistis, mycodermatitis. In the lyrate nightshade gelatin of this invention, the abstract from lyrate is 0.5-20%, gelatin matrix 1.5-30%, transdermal accelerant 0.05-8.0%, the moisture remaining agent 1.0-20%, the antiseptic 0.15-8.0% of the weight of the gelatin.

The invention provides an external used medicine for dermatologic diseases, which is characterized in that phellodendron, lightyellow sophora root, common cnidium fruit, broom cypress fruit, pericarpium zanthoxyli and chloroxylenol are used as active medicine ingredients, and the invention is prepared by mixing the active medicine ingredients with assistant ingredients that are acceptable in preparing external used medicines, wherein, the weight proportions of the active medicine ingredients are as follow: 2-8 parts of phellodendron, 1-5 parts of lightyellow sophora root, 1-5 parts of common cnidium fruit, 1-5 parts of broom cypress fruit, 4-15 parts of pericarpium zanthoxyli and 0.1-5 parts of chloroxylenol. The medicine is a combination of traditional Chinese medicine and western medicine, with the sterilizing rate of over 99.9%, and can effectively sterilize diverse bacteria and fungi such as golden brown staphylococcus, colon bacillus, candida albicans, etc. The external used medicine has quick effect on dermatologic diseases, has high cure rate, few side effects and no drug resistance, and can cure both symptom and root diseases.

The invention discloses a traditional Chinese medicine composition for treating fungus-caused skin diseases of cats and dogs and belongs to the technical field of pet disease prevention and treatment. The traditional Chinese medicine composition comprises 12-20g of golden larch bark, 12-20g of clove, 12-20g of purslane, 10-20g of radix sophorae flavescentis, 10-20g of broom cypress fruit, 10-20g of radix stemonae and 10-20g of pericarpium zanthoxyli. The traditional Chinese medicine composition produces effects fast, has substantial curative effects and no toxic or side effect and realizes treatment on both symptoms and root causes. The traditional Chinese medicine composition has multilevel, multi-process and multi-target spot effects, can improve immunity and has the advantages which does not belong to chemical drugs. The traditional Chinese medicine composition solves the problem that the antifungal western medicine prevents fungus-caused skin disease recurrence difficultly, prevents fungus-caused skin disease resistance to the antifungal western medicine, and reduces a treatment cost of the fungus-caused skin diseases of cats and dogs.

A Chinese medicine for treating fungal dermatopathy and biomhidrosis by both interior and exterior applications is prepared from 12 Chinese-medicinal materials including tetrandra root, flavescent sophora root, bletilla tuber, white mustard seed, etc. Its advantages are high curative effect and no toxic by-effect.

The invention discloses a medicinal tincture for treating fungal diseases. The medicinal tincture consists of the following components in part by weight: 4 to 6 parts of pseudolarix, 4 to 6 parts of belvedere fruit, 4 to 6 parts of selinum japenious seed, 2 to 4 parts of coptis root, 2 to 4 parts of phellodendron, 3 to 4 parts of baikal skullcap root, 2 to 3 parts of rhubarb, 2 to 4 parts of lightyellow sophora root, 2 to 3 parts of sessile stemona root, 2 to 3 parts of honeysuckle, 3 to 4 parts of dandelion and 3 to 4 parts of weeping forsythia. The medicinal tincture is prepared by the following steps of: mixing the components to prepare Chinese medicinal powder, and putting the Chinese medicinal powder into a closed container; adding 1,000 to 1,500 parts of 50 to 70 percent ethanol, covering the medicinal powder, impregnating and stirring, pouring supernatant in the container out for later use after 5 to 6 days; and mixing 40 to 60g of salicylic acid, 90 to 110g of benzoic acid and 830 to 870ml of supernatant to prepare 1,000ml of the medicinal tincture. Compared with the prior art, the medicinal tincture is an externally applied medicine integrating traditional and western medicines, small in side effect, simple in preparation method, prepared from readily available raw materials and obvious in curative effect.

The invention relates to a radish seed extract as well as a preparation method and an application of a radish seed extract. The preparation method of the radish seed extract comprises the following steps: soaking disinfected radish seeds with water; pulping all the substances in a soaking container into homogenate; centrifuging the obtained homogenate; and taking supernate, thus obtaining the radish seed extract. Experiments prove that the extract has the function of restraining funguses capable of causing skin diseases; an inhibition zone experiment indicates that the inhibition zone diameter of the extract is obviously larger than that of a control group; a skin disease therapeutic experiment indicates that the therapeutic effect of the extract is obviously better than that of the control group, the curative effect is rapid, and plainness without side effect can be realized; and in addition, the preparation method of the extract is simple, the raw material source is wide, and the cost is low, thus the extract in the invention has the characteristic of wide application prospect in the field of treating fungal skin diseases.

The invention discloses a compound abamectin transdermal solution for pets, and a preparation method and use method thereof, and relates to the field of veterinary preparations. The compound abamectintransdermal solution for pets comprises the following raw materials in parts by weight: 0.5% of abamectin B1, 10%-25% of pyrethrin, 1%-5% of a cortex pseudolaricis extract, 0.5%-5% of a cortex meliaeextract, 0.5%-3% of menthol, 2%-8% of azone, 3%-15% of propylene glycol and the balance of an organic solvent. The compound abamectin transdermal solution can be used for treating parasitic diseases,secondary infection bacteria, fungal skin diseases and the like of pets, has a remarkable treatment effect on the secondary infection bacteria and fungal skin diseases of pets due to parasitic diseases, has the effects of relieving pain, diminishing swelling, diminishing inflammation and relieving itching, and can remarkably improve symptoms of skin diseases of pets. Compared with a single abamectin transdermal solution, the compound abamectin transdermal solution disclosed by the invention is wider in insect-resistant spectrum and stronger in insect-resistant activity.

The invention relates to an isolated culture method of a Beauveria bassiana BB-7 strain and an inhibition effect of metabolites of the Beauveria bassiana BB-7 strain on animal fungal skin diseases. The strain is preserved in China Center for Type Culture Collection at Wuhan University, Wuhan, China, on April 30, 2019, with the postcode of 430072 and the preservation number of CTCC NO: M2019260; and the strain has been subjected to whole genome sequencing. The fungal metabolites have good antibacterial activity on three animal pathogenic bacteria, i.e., Sabourauditeslanosus, Microsporumgypseum and Trichophyton mentagrophytes.

The invention discloses a skin wound repairing hydrogel and a preparation method thereof. The skin wound repairing hydrogel contains aloe gum, chitosan, beta-glycerophosphate sodium and water, and has a pH value of 7.0 to 7.5. The preparation steps mainly include: at 2-10°C, mix 1-4% (w / v) chitosan solution and aloe gum at a volume ratio of 1:1-2, and then add β-sodium glycerophosphate solution dropwise , adjust the pH value of the solution to 7.0-7.5, and form a gel at 4-50°C. The skin wound repairing hydrogel of the present invention can promote the generation of skin capillaries, is beneficial to tissue growth, protects wound nerve endings, and relieves pain. It can be used for treating purulent skin diseases, superficial fungal skin diseases, skin trauma, and ultraviolet dermatitis. Anti-inflammatory, sterilizing, analgesic, absorbing heat, reducing swelling, softening skin, relieving pain, and improving scars.

The invention discloses a new use of Liushen pills in preparing medicines for preventing and treating dermatomycoses. Pharmacodynamics study on fungal resistance of Liushen pills is carried out by use of lots of experiments and results indicate that the Liushen pills have inhibiting effect on all common skin pathomycete and obvious itching relieving effect. Besides, clinical study on treating tinea pedis, tinea corporis and tinea cruris by use of the Liushen pills is still carried out and results indicate that the Liushen pills have excellent treatment effect on the dermatomycoses such as the tinea pedis, the tinea corporis and the tinea cruris. Due to the use of the Liushen pills in treating the dermatomycoses, the uses of Chinese patent medicines are expanded, and the Liushen pills have the advantages of good curative effect, no drug resistance, no easy relapse and the like, and thus have excellent clinical use prospect.

The invention discloses a medicinal tincture for treating fungal diseases. The medicinal tincture consists of the following components in part by weight: 4 to 6 parts of pseudolarix, 4 to 6 parts of belvedere fruit, 4 to 6 parts of selinum japenious seed, 2 to 4 parts of coptis root, 2 to 4 parts of phellodendron, 3 to 4 parts of baikal skullcap root, 2 to 3 parts of rhubarb, 2 to 4 parts of lightyellow sophora root, 2 to 3 parts of sessile stemona root, 2 to 3 parts of honeysuckle, 3 to 4 parts of dandelion and 3 to 4 parts of weeping forsythia. The medicinal tincture is prepared by the following steps of: mixing the components to prepare Chinese medicinal powder, and putting the Chinese medicinal powder into a closed container; adding 1,000 to 1,500 parts of 50 to 70 percent ethanol, covering the medicinal powder, impregnating and stirring, pouring supernatant in the container out for later use after 5 to 6 days; and mixing 40 to 60g of salicylic acid, 90 to 110g of benzoic acid and 830 to 870ml of supernatant to prepare 1,000ml of the medicinal tincture. Compared with the prior art, the medicinal tincture is an externally applied medicine integrating traditional and western medicines, small in side effect, simple in preparation method, prepared from readily available raw materials and obvious in curative effect.

The invention discloses an external-use bactericide for treating deep dermatomycoses. The external-use bactericide comprises, by mass, 3-12 parts of glycine, 1-9 parts of boracic acid, 3-8 parts of tannin, 5-12 parts of salicylic acid and 6-12 parts of benzoic acid. According to the external-use bactericide, various antibacterial, anti-inflammatory and convergent chemical compounds are matched reasonably, and the components are processed according to corresponding proportion to obtain the product of three dosage forms; patients choose different dosage forms according to diseases, under action of the drug and by a targeted positioning therapy method, efficacy of the drug directly acts on the affected part to achieve remarkable treatment effect to deep dermatomycoses such as tinea of feet and hands, onychomycosis and urticaria and various tinea diseases, besides, the drug has no irritation effect to skin, patients do not need to avoid certain foods when taking the drug, and thus, the drug is suitable for various groups of people.

The invention discloses a voriconazole compound aqueous emulsion preparation for treating fungal skin diseases in pets, and relates to the technical field of a medicine. The preparation mainly consists of the following materials according to a formula: voriconazole, tinidazole and dexamethasone, and further consists of the following adjuvant materials: tween-80, propanediol and pure water, wherein the mass percentage of the formula materials is at (5-15g) to (3-8g) to (0.5-2g) to (25-35ml) to (25-35ml) to (80-120ml) of the voriconazole to the tinidazole to the dexamethasone to the tween-80 to the propanediol to the pure water; and a preparation technology of the formula comprises the following processes: (1) heating the tween-80 (30ml) and the propanediol (30ml) in a container; (2) while heating, pouring the voriconazole (10g), the tinidazole (5g) and the dexamethasone (1g); (3) heating until the materials are dissolved, and stopping warming up; and (4) adding the pure water to 100ml, and uniformly stirring, so that the preparation is obtained. The preparation disclosed by the invention has the beneficial effects that the preparation can solve difficulties in skin repair treatment of fungal pyoderma in the pets; the preparation is broad in economic benefit and prospect and is considerable in benefit; and the preparation has the advantages of simple materials, reasonable design, low preparation cost and the like.

The invention relates to a skin antibacterial medicine composition as well as a preparation method and an application thereof, and belongs to the technical field of medicines. The composition is prepared from the following materials by weight percent: 1% to 3% of benzoic acid, 1% to 3% of salicylic acid, 0.5% to 5% of clove oil and 0.5% to 2% of borneol. The antibacterial and itching-resistant effects of the composition can be further enhanced after 0.3% of baicalin, 0.3% of honeysuckle extract, 0.5% of cetirizine hydrochloride and 1% of sodium chloride are added into the composition. The pharmacodynamic test proves that the composition provided by the invention has good effects for treating eczemas and fungal skin diseases.

The invention discloses a beriberi prevention and treatment wet tissue and a preparation method thereof. The wet tissue consists of a non-woven fabric and a long-acting fungicidal disinfectant. The long-acting fungicidal disinfectant is prepared from, by weight, 40-60 parts of 95% ethyl alcohol, 0.2-4 parts of a fungicidal disinfecting agent, 0.1-1.5 parts of a cool itching-relieving agent and 40-50 parts of distilled water. The beriberi prevention and treatment wet tissue is prepared according to a normal process and is portable and remarkably effective, the fungicidal rate is higher than 99.9%, and efficacies of itching relieving and deodorizing are achieved. The beriberi prevention and treatment wet tissue is excellent in fungicidal effect and long in efficacy lasting time, can be usedfor fungal skin diseases such as beriberi and tinea pedis caused by fungal infection to play a role in itching relieving, slough removing, tissue regeneration promoting and skin normal function recovery promoting and is widely applicable to the field of the skin diseases caused by fungi.

The invention discloses a shower gel for treating fungal skin diseases of pets and a preparation method thereof, and belongs to the technical field of pet supplies. The shower gel comprises 68.65%-82.74% of water, 10%-14% of sodium lauryl polyoxyethylene ether sulfate, 1.5%-3% of coconut oil diethanolamide, 2%-4% of cocamidopropyl betaine, 0.5%-1.5% of decyl glucoside, 1%-3% of glycerin, 0.1%-0.2% of disodium ethylene diamine tetraacetate, 0.25%-0.45% of maltodextrin, 0.1%-0.3% of menthol, 1.0%-1.5% of citric acid, 0.1%-0.2% of kathon, 0.1%-0.5% of essence, 0.4%-2.2% of sodium chloride, 0.2%-0.4% of PEG-7 glyceryl cocoate, and 0.01%-0.1% of nanometer sulfur. The shower gel can achieve high sterilization rate on fungal skin diseases, and is free of toxicity and no drug resistance.

The invention provides an enconazole external liquid preparation, which is prepared by mixing enconazole, a solvent capable of dissolving enconazole and an emulsifier, and tests show that the appearance, the pH value and the purity of the enconazole external liquid preparation are basically unchanged after three months, so that the enconazole external liquid preparation can stably exist and is noteasy to degrade; the enconazole external liquid preparation disclosed by the invention can be used for effectively treating canine fungal skin diseases, and is simple in use method and good in antibacterial effect; the enconazole external liquid preparation disclosed by the invention contains menthol, and the external liquid preparation added with menthol has a relatively obvious relieving effecton discomfort, such as pruritus, of some pets when being used for treating fungal skin diseases; the enconazole external liquid preparation provided by the invention is mild to dogs and has no irritation to skin.

The invention discloses a rabbit hutch disinfection method for preventing fungal disease. The rabbit hutch disinfection method mainly comprises the following steps (1) cleaning up a rabbit hutch, and scouring a cage, a ground, walls, coprodeum and the like with a high-pressure water gun; (2) foaming the interior of the hutch completely with detergent, to remove oil stains on the ground and the walls; (3) washing out the interior of the hutch with a deciquam solution of 1:500, and disinfecting; and (4) closing windows and doors and an coprodeum outlet, fumigating with formaldehyde potassium permanganate, volatilizing and diffusing formaldehyde into air in a gas form, so as to denature protein and dissolve lipoid so as to achieve the purpose of killing fungus, and fumigating for 24 hours. Fungus in the hutch can be thoroughly killed after being disinfected by adopting the disinfection method, so that the transmission route is eliminated so as not to continuously infect newly transferred rabbit crowds.

The invention relates to the field of veterinary drugs, and discloses an itraconazole-terbinafine compound injection for dogs and cats and a preparation method of the compound injection.The novel compound preparation prepared by taking hydroxypropyl-beta-cyclodextrin as a carrier has the advantages of being wide in antibacterial spectrum, high in treatment effect, low in cost and the like; the product is high in inclusion rate and drug concentration, capable of meeting the treatment requirement and good in stability; the compound injection is low in toxicity, good in absorption and capable of achieving the better treatment effect on fungal skin diseases of the dogs and the cats.

The invention mainly relates to the technical field of innovative drug research and development, and discloses a drug spray agent which can inhibit the growth of fungi so as to achieve the treatment of fungal dermatosis. The invention aims to provide a traditional Chinese medicine bacteriostatic spray agent for fungal dermatosis, wherein the traditional Chinese medicine bacteriostatic spray agentis prepared by extracting effective ingredients from a natural traditional Chinese medicine plant formula by a modern pharmaceutical technology. The spray agent comprises the following raw materials in parts by weight: 20-25 parts of a raw ginger extract liquid, 10-15 parts of an aloe extract liquid, 10-15 parts of a chrysanthemum morifolium extract liquid, 5-10 parts of pericarpium citri reticulatae, 5-10 parts of Sichuan pepper, 5-10 parts of honeysuckle, and 5-10 parts of semen cassiae. The drug has the functions of breaking walls and penetrating muscles, expelling toxin, and preventing andtreating fungal dermatosis. With traditional Chinese medicine extraction, the spray agent can avoid drug resistance, quickly kill pathogenic bacteria, avoid recurrence and alleviate patient pain, andhas no toxic or side effects and almost no harm to skin; a variety of plant traditional Chinese medicine ingredients can be antibacterial and bacteriostatic, and the device is quite convenient to spray and does not affect travel.

The invention relates to a Chinese medicinal composition for treating skin diseases. The Chinese medicinal composition is prepared by stir-frying various Chinese herbal medicines such as phellodendron, baical skullcap root, manchurian wildginger, schizonepeta spike, bulbus fritilariae, golden larch bark, sulphur, realgar, toad venom, musk, mint rice, plant soot, salicylic acid and the like over slow fire, grinding accurately, mixing with badger fat, antelope oil and the like, grinding again and extracting. The Chinese medicinal composition can remove abnormal phlegmatic temperament, bile fluid and sepsis and relieve swelling and itching, and is used for treating parapsoriasis guttata (psoriasis), tinea manuum, tinea corporis, tinea pedis, tinea versicolor, intractable dermatitis, neurodermatitis, fungal skin diseases, leuconychia, purulent skin diseases, facial pityriasis, pityriasis rosea, seborrheic dermatitis, prurigo nodularis, scabies, eczema, herpes, acnes and the like.

The invention discloses a pharmaceutical preparation for removing skin bromidrosis, peculiar smell, hemorrhoid and psoriasis, relates to a novel purpose of edible acetic acid preparation- vinegar in the pharmaceutical field, and aims to solve the technical problem that the edible acetic acid preparation-vinegar can be used to kill poisonous skin germs. The technical point for solving the problem is to perform diluting and heating treatment on the edible acetic acid preparation-vinegar. The main purpose of the pharmaceutical preparation is to treat chronic refractory germ fungal skin diseases such as psoriasis, hemorrhoid, sweaty feet, foot odor, bromhidrosis, and removes skin bromidrosis and peculiar smell.

The invention discloses external shower gel for preventing and treating dermatomycosis and gynecological diseases based on traditional Chinese medicine materials and a preparation and processing method of the external shower gel. The external shower gel is prepared by mixing the following raw materials in percentage by weight: 85%-92% of traditional Chinese medicine liquid, 1%-3% of surface active agent, 0.3%-1.5% of vegetable oil and fat, 0.15%-0.55% of thickening agent, 0.15%-0.55% of corrosion remover, 1%-3% of emulsifying agent, 0.5%-1.1% of antioxidant, 0.06%-0.14% of PH conditioning agent, 0.2%-0.6% of essence and 5%-10% of deionized water. The traditional Chinese medicine liquid is prepared from the following raw materials in percentage: 11%-12% of herba hedyotis diffusae, 10%-11% of herba patriniae, 8.5%-9% of radix et rhizoma rhei, 14%-16% of cortex phellodendri, 11%-13.6% of herba centellae, 15%-19% of fructus cnidii, 17%-20% of folium artemisiae argyi and 8%-13.5% of deionized water. The external shower gel has good performance of preventing and treating dermatomycosis and gynecological diseases.

The Wudalianchi hair fern mineral spring effervescent tablet and a preparation method thereof relate to the hair fern mineral spring effervescent tablet. The present invention aims to solve the problem of insufficient extraction of the active ingredients of the existing Trichophyllum chinensis in Wudalianchi, the effect cannot be effectively brought into play, and the application effect is not good; Corticosteroid bath products have great harm to the body and skin. According to the number of parts by mass, it is composed of 5-30 parts of Wudalianchi hair fern extract, 5-20 parts of Wudalianchi bicarbonate mineral water extract, 5-20 parts of Wudalianchi volcanic mud powder, 5-50 parts of acid source, 5-50 parts of Made with 1 part alkali, 2-20 parts lubricant, 0.1-50 parts filler, and 0.1-5 parts essential oil. The preparation method is as follows: extracting Wudalianchi hairy fern, mineral water extract and Wudalianchi volcanic mud powder; mixing it with acid source, alkali source, lubricant and filler.

The invention relates to the technical field of medicines, and particularly discloses application of hypericin in preparation of medicines for treating fungal skin diseases. The invention provides a new application of hypericin in preparation of a medicine for treating fungal skin diseases, and researches find that the medicine for treating fungal skin diseases prepared from hypericin not only has a high cure rate on fungal skin diseases, but also has the advantages of small side effect and low recurrence rate compared with other oral and external medicines, and has a wide application prospect in the field of medicine for treating fungal skin diseases. A new breakthrough point is provided for treatment of fungal skin diseases.